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Assessment of the anterior scleral thickness in central serous chorioretinopathy patients by optical coherence tomography

Abstract

Purpose

To assess the anterior scleral thickness (AST) and describe the presence of a visible supraciliary space (SCS) in central serous chorioretinopathy (CSC) patients by swept-source optical coherence tomography (SS-OCT).

Study design

Cross-sectional comparative study.

Material and Methods

Three groups were studied: 1) 64 eyes of 54 patients with CSC with persistent subretinal fluid (SRF); 2) 42 fellow eyes of CSC patients without SRF; 3) 65 eyes of 65 controls matched by age, sex and axial length (AL). The AST was measured in the temporal and nasal quadrants at 0, 1, and 2 mm from the scleral spur by SS-OCT. The presence of a visible SCS was also assessed.

Results

No differences were observed in the AST0 among the three groups (p≥ 0.665). The temporal AST1 was significantly thicker in the CSC group (530.3 ±67.1 µm) than in the controls (505.5 ±73.9; p=0.041). Mean AST2 was also thicker in the CSC group and the fellow eyes both for the temporal (519.4 ±89.1 µm and 519.8 ±98.5 µm respectively) and nasal quadrants (564.2 ±124.9 µm and 570.5 ±131.0 µm) than in the controls (450.1 ±76.8 and 473.3 ±111.6 µm) (all p≤0.001). A visible SCS was detected in the eyes of 8 CSC patients, in 4 fellow eyes and only in 1 control eye.

Conclusions

AST measured by SS-OCT was significantly greater in CSC eyes than in healthy eyes. Also, a visible SCS was detected in CSC eyes. Thus, thicker sclera in CSC eyes could be associated with the physiopathology of this disease.

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Correspondence to José Ignacio Fernández-Vigo.

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Conflicts of interest

J. I. F. Vigo, None; F. J. M. Morillo, None; H. Shi, None; F. L. Yang, None; B. B. Blasco, None; N. G. Villahoz, None; J. D. López, None; J. G. Feijóo, None.

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Corresponding Author: José Ignacio Fernández-Vigo

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Fernández-Vigo, J.I., Moreno-Morillo, F.J., Shi, H. et al. Assessment of the anterior scleral thickness in central serous chorioretinopathy patients by optical coherence tomography. Jpn J Ophthalmol (2021). https://doi.org/10.1007/s10384-021-00870-4

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Keywords

  • Central serous chorioretinopathy
  • Optical coherence tomography
  • Anterior scleral thickness
  • Supraciliary space
  • Sclera