Skip to main content

Epidemiologic study of rhegmatogenous retinal detachment in Japan from the Diagnosis Procedure Combination database over a 2-year period (2014–2015)



To determine the incidence of rhegmatogenous retinal detachments (RRDs) and proliferative vitreoretinopathies (PVRs) and their distribution by age and sex in hospitalized patients in Japan.

Study design

Retrospective nationwide observational study.


Information on the number of inpatients primarily diagnosed with RRD or PVR and their age and sex were collected from the Diagnosis Procedure Combination (DPC) database for 2014 and 2015. The incidence was determined using the Japanese population report published by the Public Management Ministry’s Statistics Bureau.


The incidence of RRD in these hospitalized patients was 10.9/100,000, with 15.0/100,000 in men and 7.1/100,000 in women, and that of PVR was 2.1/100,000, with 2.9/100,000 in men and 1.3/100,000 in women. The incidence in men was twice that in women for both RRD and PVR. The distribution of RRD by age was monophasic, with a peak at 50 years for both sexes, and that of PVR was at peak in the 60 s for men and in the 70 s for women. PVR was more common than RRD in children aged younger than 10 years, but the incidence of RRD was higher in the other age groups.


A study of the DPC database can provide useful information on the incidences of RRD and PVR in hospitalized patients in Japan.

This is a preview of subscription content, access via your institution.

Fig. 1
Fig. 2
Fig. 3


  1. 1.

    Mitry D, Charteris DG, Fleck BW, Campbell H, Singh J. The epidemiology of rhegmatogenous retinal detachment: geographical variation and clinical associations. Br J Ophthalmol. 2010;94:678–84.

    CAS  Article  Google Scholar 

  2. 2.

    Mowatt L, Shun-Shin G, Price N. Ethnic differences in the demand incidence of retinal detachments in two districts in the West Midlands. Eye (Lond). 2003;17:63–70.

    CAS  Article  Google Scholar 

  3. 3.

    Sasaki K, Ideta H, Yonemoto J, Tanaka S, Hirose A, Oka C. Epidemiologic characteristics of rhegmatogenous retinal detachment in Kumamoto, Japan. Graefes Arch Clin Exp Ophthalmol. 1995;233:772–6.

    CAS  Article  Google Scholar 

  4. 4.

    Sakamoto T, Kawano S, Kawasaki R, Hirakata A, Yamashita H, Yamamoto S, et al. Japan-Retinal Detachment Registry Report I: preoperative findings in eyes with primary retinal detachment. Jpn J Ophthalmol. 2020;64:1–12.

    Article  Google Scholar 

  5. 5.

    Wong TY, Tielsch JM, Schein OD. Racial difference in the incidence of retinal detachment in Singapore. Arch Ophthalmol. 1999;117:379–83.

    CAS  Article  Google Scholar 

  6. 6.

    Ouertani A, Zhioua R, el Euch M, Mili I. Retinal detachment in young patients. Article in French J Fr Ophtalmol. 1994;17:388–93.

    CAS  PubMed  Google Scholar 

  7. 7.

    Read SP, Aziz HA, Kuriyan A, Kothari N, Davis JL, Smiddy WE, et al. Retinal detachment surgery in a pediatric population: visual and anatomic outcomes. Retina. 2018;38:1393–402.

    Article  Google Scholar 

  8. 8.

    Soheilian M, Ramezani A, Malihi M, Yaseri M, Ahmadieh H, Dehghan MH, et al. Clinical features and surgical outcomes of pediatric rhegmatogenous retinal detachment. Retina. 2009;29:545–51.

    Article  Google Scholar 

  9. 9.

    Okamura S, Kobayashi R, Sakamaki T. Case-mix payment in Japanese medical care. Health Policy. 2005;74:282–6.

    Article  Google Scholar 

  10. 10.

    Hayashida K, Murakami G, Matsuda S, Fushimi K. History and profile of Diagnosis Procedure Combination (DPC): development of a real data collection system for acute inpatient care in Japan. J Epidemiol. 2021;31:1–11.

    Article  Google Scholar 

  11. 11.

    Fukuhara T. Geographical analysis of aneurysmal subarachnoid hemorrhage in Japan utilizing publically-accessible DPC database. PLoS ONE. 2015;10:e0122467.

    Article  Google Scholar 

  12. 12.

    Araki S, Tomioka S, Otani M, Suga S, Ichikawa S, Matsuda S, et al. Incidence and in-hospital mortality of neonatal disseminated intravascular coagulation in Japan: an observational study of a nationwide hospital claims database. J UOEH. 2019;41:295–302.

    Article  Google Scholar 

  13. 13.

    Gonzales CR, Singh S, Yu F, Kreiger AE, Gupta A, Schwartz SD. Pediatric rhegmatogenous retinal detachment: clinical features and surgical outcomes. Retina. 2008;28:847–52.

    Article  Google Scholar 

  14. 14.

    The classification of retinal detachment with proliferative vitreoretinopathy. Ophthalmology. 1983;90:121–5.

  15. 15.

    Laatikainen L, Tolppanen EM. Characteristics of rhegmatogenous retinal detachment. Acta Ophthalmol (Copenh). 1985;63:146–54.

    CAS  Article  Google Scholar 

  16. 16.

    Ueda E, Yasuda M, Fujiwara K, Hashimoto S, Ohno-Matsui K, Hata J, et al. Trends in the prevalence of myopia and myopic maculopathy in a Japanese population: the Hisayama Study. Invest Ophthalmol Vis Sci. 2019;60:2781–6.

    Article  Google Scholar 

  17. 17.

    Yokoyama T, Kato T, Minamoto A, Sugihara A, Imada M, Kuwabara R, et al. Characteristics and surgical outcomes of paediatric retinal detachment. Eye (Lond). 2004;18:889–92.

    CAS  Article  Google Scholar 

  18. 18.

    Akabane N, Yamamoto S, Tsukahara I, Ishida M, Mitamura Y, Yamamoto T, et al. Surgical outcomes in juvenile retinal detachment. Jpn J Ophthalmol. 2001;45:409–11.

    CAS  Article  Google Scholar 

  19. 19.

    Scott IU, Flynn HW Jr, Azen SP, Lai MY, Schwartz S, Trese MT. Silicone oil in the repair of pediatric complex retinal detachments: a prospective, observational, multicenter study. Ophthalmology. 1999;106:1399–407 (Discussion 407–8).

    CAS  Article  Google Scholar 

Download references


We thank Drs Ken Hayashi (Hayashi Eye Hospital, Fukuoka, Japan), Takaaki Matsui (Ohshima Eye Hospital, Fukuoka, Japan), and Kazushi Fujimoto (Fujimoto Eye Clinic, Fukuoka, Japan) for providing medical practice data. We also thank Duco Hamasaki, Professor Emeritus, Bascom Palmer Eye Institute, University of Miami, for his critical comments and valuable assistance.

Author information



Corresponding author

Correspondence to Hiroyuki Kondo.

Ethics declarations

Conflicts of interest

K. Oku, None; K. Tokutsu, Consultant fee (ASTEM); S. Matsuda, Consultant fee (YAGAMI), Lecture fee (Chugai); H. Kondo, Lecture fee (Santen, Bayer, Kowa, Senju, Otsuka, RE Medical), Grant, Lecture fee (Alcon, AMO, Novartis,).

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Corresponding Author: Hiroyuki Kondo

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (DOCX 114 KB)

About this article

Verify currency and authenticity via CrossMark

Cite this article

Oku, K., Tokutsu, K., Matsuda, S. et al. Epidemiologic study of rhegmatogenous retinal detachment in Japan from the Diagnosis Procedure Combination database over a 2-year period (2014–2015). Jpn J Ophthalmol (2021).

Download citation


  • Epidemiologic studies
  • Rhegmatogenous retinal detachment
  • Proliferative vitreoretinopathy
  • Diagnosis Procedure Combination (DPC)
  • Japanese