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Prognostic factors for successful Baerveldt glaucoma implant surgery for refractory glaucoma after multiple surgeries

Japanese Journal of Ophthalmology volume 65, pages 820–826 (2021)Cite this article

Abstract

Purpose

To determine the prognostic factors for success 3 years after Baerveldt glaucoma implant (BGI) surgery.

Study design

Single-center retrospective clinical study.

Methods

We analyzed 27 eyes (24 patients) treated with BGI surgery between 2012 and 2016 at Osaka University Hospital. Patients were followed for a minimum of 3 years postoperatively. We analyzed the success rates and risk factors. Failure was defined as the need for additional surgery for IOP reduction, loss of light perception, and intraocular pressure (IOP) ≧22 mmHg (definition 1) or ≧17 mmHg (definition 2) at two consecutive follow-up visits.

Results

The mean number of previous eye surgeries was 4.1 ± 3.3. The success rates were 81.5% and 77.8%, respectively, 1 year and 3 years after surgery based on definition 1 and 51.9% and 48.2%, respectively, based on definition 2. The early and late surgical complication rates, respectively, were 29.6% and 22.2%. An IOP 2 months after BGI surgery of ≧17 mmHg and the number of previous eye surgeries were significant risk factors for failure based on definition 2.

Conclusion

The long-term results and complication rates after BGI surgery for refractory glaucoma in our hospital were similar to previous reports, and the IOP 2 months after BGI surgery and the number of previous eye surgeries were associated with the prognosis.

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Acknowledgements

We thank Lynda Charters of Medical International for English language editing. This study was supported by Grants-in-Aid for Scientific Research C (no. 18K09406) and Grants-in-Aid for Early-Career Scientists (no. 20K18379) from the Ministry of Education, Culture, Sports, Science, and Technology.

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Authors and Affiliations

  1. Department of Ophthalmology, Osaka University Graduate School of Medicine, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan

    Kenji Matsushita, Rumi Kawashima & Ryo Kawasaki

  2. Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Japan

    Kohji Nishida

Authors
  1. Kenji Matsushita
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  2. Rumi Kawashima
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  3. Ryo Kawasaki
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Corresponding author

Correspondence to Kenji Matsushita.

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Conflict of interest

K. Matsushita, None; R. Kawashima, None; R. Kawasaki, None; K. Nishida, None.

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Corresponding Author: Kenji Matsushita

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Matsushita, K., Kawashima, R., Kawasaki, R. et al. Prognostic factors for successful Baerveldt glaucoma implant surgery for refractory glaucoma after multiple surgeries. Jpn J Ophthalmol 65, 820–826 (2021). https://doi.org/10.1007/s10384-021-00864-2

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  • DOI: https://doi.org/10.1007/s10384-021-00864-2

Keywords

  • Baerveldt glaucoma implant (BGI)
  • Refractory glaucoma
  • Late complications
  • Prognostic factor