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Two cases of repeating recurrences and spontaneous closures of macular holes in vitrectomized eyes

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Three eyes of 2 cases had repeating recurrences and spontaneous closures of macular holes (MHs) after vitrectomy.


A 66-year-old man had rhegmatogenous retinal detachment (RRD) in his left eye and underwent vitrectomy with successful retinal reattachment. A full-thickness MH developed 1 year after the vitrectomy and spontaneously closed 1 month later. Opening and spontaneous closure of the MH recurred an additional 4 times over 7 years. An 80-year-old man had suffered intraocular lens (IOL) dislocation and underwent vitrectomy in his left eye. An MH developed in the eye 6 years and 3 months after the vitrectomy. Repeated opening and spontaneous closure of the MH occurred twice in the left eye. The same patient also suffered IOL dislocation and underwent vitrectomy in his right eye. An MH also developed in the right eye 2 years and 9 months after the vitrectomy. Repeated opening and spontaneous closure of the MH occurred 3 times in the right eye.


The visual acuity was maintained at the last visit in both cases.


MHs in vitrectomized eyes can show repeated recurrence and spontaneous closure.

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Correspondence to Takamasa Mori.

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T. Mori, None; S. Kitamura, None; H. Sakaguchi, None; K. Nishida, None; M. Ohji, Grant (Alcon, HOYA, Kowa Pharmaceutical, Novartis, Otsuka Pharmaceutical, Pfizer, Santen Pharmaceutical, Senju Pharmaceutical, Topcon), Consultant fees (Alcon, Allergan, Bayer, Novartis, Santen Pharmaceutical), Lecture fees (Alcon, Bausch+Lomb, Bayer, Carl Zeiss, Chugai Pharmaceutical, Chuo Sangio, HOYA, Kowa Pharmaceutical, MSD, Novartis, Otsuka Pharmaceutical, Pfizer, RE medical, Santen Pharmaceutical, Sanwa Kagaku Kenkyusho, Senju Pharmaceutical, Topcon).

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Mori, T., Kitamura, S., Sakaguchi, H. et al. Two cases of repeating recurrences and spontaneous closures of macular holes in vitrectomized eyes. Jpn J Ophthalmol 62, 467–472 (2018).

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