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Comparison of visual acuity, metamorphopsia, and aniseikonia in patients with an idiopathic epiretinal membrane

Japanese Journal of Ophthalmology volume 62, pages 280–285 (2018)Cite this article

Abstract

Purpose

The clinical course of reduced visual acuity, metamorphopsia, and aniseikonia are dissimilar in patients with an epiretinal membrane (ERM). We measured and compared the best-corrected visual acuity (BCVA), metamorphopsia, and aniseikonia of patients with ERM.

Methods

We measured metamorphopsia and aniseikonia horizontally as well as vertically with the M-CHART (MH and MV) and New Aniseikonia Test (NATH and NATV) in 61 patients with unilateral idiopathic ERM. We compared the BCVA with the other values. Comparisons between the MH and the NATV and between the MV and the NATH were performed, because the MH assesses vertical metamorphopsia, and the MV, horizontal metamorphopsia.

Results

BCVA was not significantly correlated with the other values (MH vs BCVA: P = .69; MV vs BCVA: P = .114; NATH vs BCVA: P = .656; NATV vs BCVA: P = .935). The MH and NATV magnitudes were significantly correlated, but the correlation coefficient was small (P = .007, r = 0.343); no significant correlation was found between the MV and NATH magnitudes (P = .065). We found patients with aniseikonia, but no metamorphopsia (n = 6), and more patients with metamorphopsia, but no aniseikonia (n = 11). Only 23 patients had coincident directions of metamorphopsia and aniseikonia.

Conclusions

The magnitudes of metamorphopsia and aniseikonia were not closely correlated and their directions did not coincide in most patients. Neither the M-CHARTS nor the NAT measurements correlated with the BCVA. Quantitative testing of metamorphopsia and aniseikonia in addition to that for BCVA is necessary to assess visual function in patients with ERM.

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References

  1. Matsumoto C, Arimura E, Okuyama S, Takada S, Hashimoto S, Shimomura Y. Quantification of metamorphopsia in patients with epiretinal membranes. Invest Ophthalmol Vis Sci. 2003;44:4012–6.

    Article  PubMed  Google Scholar 

  2. Kinoshita T, Imaizumi H, Okushiba U, Miyamoto H, Ogino T, Mitamura Y. Time course of changes in metamorphopsia, visual acuity, and OCT parameters after successful epiretinal membrane surgery. Invest Ophthalmol Vis Sci. 2012;53:3592–7.

    Article  PubMed  Google Scholar 

  3. Tachibana T, Yoshida S, Kobayashi Y, Nakama T, Ishikawa K, Sengoku A, et al. Differential improvement of vertical and horizontal metamorphopsia scores after epiretinal membrane vitrectomy with ILM peeling. Acta Ophthalmol. 2015;93(8):e681–2.

    Article  PubMed  Google Scholar 

  4. Nomoto H, Matsumoto C, Arimura E, Okuyama S, Takada S, Hashimoto S, et al. Quantification of changes in retinal contraction in eyes with spontaneous separation of idiopathic epiretinal membrane. Eye. 2013;27:924–30.

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  5. Okamoto F, Sugiura Y, Okamoto Y, Hiraoka T, Oshika T. Associations between metamorphopsia and foveal microstructure in patients with epiretinal membrane. Invest Ophthalmol Vis Sci. 2012;53:6770–5.

    Article  PubMed  Google Scholar 

  6. Watanabe A, Arimoto S, Nishi O. Correlation between metamorphopsia and epiretinal membrane optical coherence tomography findings. Opthalmology. 2009;116:1788–93.

    Article  Google Scholar 

  7. Okamoto F, Sugiura Y, Okamoto Y, Hiraoka T, Oshika T. Inner nuclear layer thickness as a prognostic factor for metamorphopsia after epiretinal membrane surgery. Retina. 2015;10:2107–14.

    Article  Google Scholar 

  8. Awaya S, Sugawara M, Horibe F, Torii F. The, “new aniseikonia tests” and its clinical applications [in Japanese]. Nippon Ganka Gakkai Zasshi. 1982;86:217–22.

    CAS  PubMed  Google Scholar 

  9. Hisada H, Awaya S. Aniseikonia of central serous chorioretinopathy [in Japanese]. Nippon Ganka Gakkai Zasshi. 1992;96:369–74.

    CAS  PubMed  Google Scholar 

  10. Ugarte M, Williamson TH. Aniseikonia associated with epiretinal membrane. Br J Ophthalmol. 2005;89:1576–80.

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  11. De Wit GC. Retinally-induced aniseikonia. Binocul Vis Strabismus Q. 2007;22:96–101.

    PubMed  Google Scholar 

  12. Okamoto F, Sugiura Y, Okamoto Y, Hiroaka T, Oshika T. The time course of changes in aniseikonia and foveal microstructure after vitrectomy for epiretinal membrane. Ophthalmology. 2014;121:2255–60.

    Article  PubMed  Google Scholar 

  13. Enoch JM, Schwartz A, Chang D, Hirose H. Aniseikonia, metamorphopsia and perceived entoptic pattern: some effects of a macular epiretinal membrane, and the subsequent spontaneous separation of the membrane. Ophthalmic Physiol Opt. 1995;4:339–43.

    Article  Google Scholar 

  14. De Wit GC, Muraki CS. Field-dependent aniseikonia associated with epiretinal membrane: a case study. Ophthalmology. 2006;113:58–62.

    Article  PubMed  Google Scholar 

  15. Benegas NM, Egbert J, Engel WK, Kushner BJ. Diplopia secondary to aniseikonia associated with macular disease. Arch Ophthalmol. 1999;117:896–9.

    CAS  Article  PubMed  Google Scholar 

  16. Michels RG. Vitrectomy for macular pucker. Ophthalmology. 1984;91:1384–8.

    CAS  Article  PubMed  Google Scholar 

  17. Michels RG. A clinical and histopathologic study of epiretinal membranes affecting the macula and removed by vitreous surgery. Trans Am Ophthalmol Soc. 1982;80:580–656.

    CAS  PubMed  PubMed Central  Google Scholar 

  18. Tanikawa A, Horiguchi M, Kondo M, Suzuki S, Terasaki H, Miyake Y. Abnormal focal macular electroretinograms in eyes with idiopathic epimacular membrane. Am J Ophthalmol. 1999;127:559–64.

    CAS  Article  PubMed  Google Scholar 

  19. Hosoda Y, Ooto S, Hangai M, Oishi A, Yoshimura N. Foveal photoreceptor deformation as a significant predictor of postoperative visual outcome in idiopathic epiretinal membrane surgery. Invest Ophthalmol Vis Sci. 2015;56:6387–93.

    Article  PubMed  Google Scholar 

  20. Watanabe A, Arimoto S, Nishi O. Correlation between metamorphopsia and epiretinal membrane optical coherence tomography findings. Ophthalmology. 2009;116:1788–93.

    Article  PubMed  Google Scholar 

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Affiliations

  1. Department of Ophthalmology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan

    Atsuhiro Tanikawa, Yoshiaki Shimada & Masayuki Horiguchi

Authors
  1. Atsuhiro Tanikawa
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  2. Yoshiaki Shimada
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  3. Masayuki Horiguchi
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Corresponding author

Correspondence to Masayuki Horiguchi.

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Conflicts of interest

A. Tanikawa, None; Y. Shimada, None; M. Horiguchi, None.

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Tanikawa, A., Shimada, Y. & Horiguchi, M. Comparison of visual acuity, metamorphopsia, and aniseikonia in patients with an idiopathic epiretinal membrane. Jpn J Ophthalmol 62, 280–285 (2018). https://doi.org/10.1007/s10384-018-0581-x

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  • DOI: https://doi.org/10.1007/s10384-018-0581-x

Keywords

  • Aniseikonia
  • Epiretinal membrane
  • Metamorphopsia
  • Retina
  • Visual acuity