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Annual incidences of visual impairment during 10-year period in Mie prefecture, Japan

  • Clinical Investigation
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Abstract

Purpose

To determine the annual incidence of visual impairment in a Japanese population during a 10-year period.

Methods

We examined the physical disability certificates issued yearly between 2004 and 2013 in Mie prefecture, Japan. During this period 2468 visually impaired people were registered under the newly defined Act on Welfare of the Physically Disabled Persons’ criteria. The age, sex distribution, and causes of visual impairment were determined from the certificates.

Results

The major causes of visual impairment during the ten-year period were glaucoma (23.3%), diabetic retinopathy (17.3%), retinitis pigmentosa (12.2%), macular degeneration (9.0%), chorioretinal degeneration or high myopia (7.4%), optic atrophy (5.8%), stroke or brain tumor (5.4%) and cataracts (3.7%). The incidence of glaucoma was significantly higher throughout the period (2004–2013), and that of diabetic retinopathy was lower between 2007 and 2013. The incidence of retinitis pigmentosa did not change significantly during the 10-year period. The incidence of macular degeneration tended to increase between 2004 and 2007, but it decreased significantly between 2007 and 2013.

Conclusions

The results indicate that in Japan, the rates of the major causes of visual impairment altered in the most recent 10-year period reflecting the recent changes in the social background and advances in ocular and systemic treatment.

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References

  1. Xu L, Wang Y, Li Y, Wang Y, Cui T, Li J, et al. Causes of blindness and visual impairment in urban and rural areas in Beijing: the Beijing Eye Study. Ophthalmology. 2006;113:1134.e1–11.

    PubMed  Google Scholar 

  2. Zheng Y, Lavanya R, Wu R, Wong WL, Wang JJ, Mitchell P, et al. Prevalence and causes of visual impairment and blindness in an urban Indian population: the Singapore Indian Eye Study. Ophthalmology. 2011;118:1798–804.

    Article  PubMed  Google Scholar 

  3. Hennis AJ, Wu SY, Nemesure B, Hyman L, Schachat AP, Leske MC. Nine-year incidence of visual impairment in the Barbados Eye Studies. Ophthalmology. 2009;116:1461–8.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Stevens GA, White RA, Flaxman SR, Price H, Jonas JB, Keeffe J, et al. Global prevalence of vision impairment and blindness: magnitude and temporal trends, 1990–2010. Ophthalmology. 2013;120:2377–84.

    Article  PubMed  Google Scholar 

  5. Nakae K, Kogure F, Nagaya Y, Mishima S. Wagakuniniokeru shikakusyogai no genkyo. J Health Welf Stat (Kousei no Shihyo). 1991;38:13–22.

    Google Scholar 

  6. Nakae K, Masuda K, Ishibashi T. Recent causes of visual disturbances in Japan—comparison with causes 15 years ago. J Clin Exp Med (Igaku no Ayumi). 2008;225:691–3.

    Google Scholar 

  7. Wako R, Yasukawa T, Kato A, Omori T, Ishida S, Ishibashi T, et al. Causes and prevalence of visual impairment in Japan. Nippon Ganka Gakkai Zasshi. 2014;118:495–501.

    PubMed  Google Scholar 

  8. Ikesugi K, Tsukitome H, Yagi T, Yamaguchi T, Tamei I, Sasoh M, et al. Causes of visual impairment in Mie prefecture during a 5-year period. Nippon Ganka Gakkai Zasshi. 2010;114:505–11.

    PubMed  Google Scholar 

  9. Ikesugi K, Sasoh M, Uji Y. Causes of visual impairment in those below 40 years of age. J Eye (Atarashii Ganka). 2011;28:743–6 (in Japanese).

    Google Scholar 

  10. Tielsch JM, Sommer A, Katz J, Royall RM, Quigley HA, Javitt J. Racial variations in the prevalence of primary open-angle glaucoma. The baltimore eye survey. JAMA. 1991;266:369–74.

    Article  CAS  PubMed  Google Scholar 

  11. Iwase A, Suzuki Y, Araie M, Yamamoto T, Abe H, Shirato S, et al. The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study. Ophthalmology. 2004;111:1641–8.

    PubMed  Google Scholar 

  12. Yamamoto S, Sawaguchi S, Iwase A, Yamamoto T, Abe H, Tomita G, et al. Primary open-angle glaucoma in a population associated with high prevalence of primary angle-closure glaucoma: the Kumejima Study. Ophthalmology. 2014;121:1558–65.

    Article  PubMed  Google Scholar 

  13. Salomon JA, Wang H, Freeman MK, Vos T, Flaxman AD, Lopez AD, et al. Healthy life expectancy for 187 countries, 1990-2010: a systematic analysis for the Global Burden Disease Study 2010. Lancet. 2012;380:2144–62.

    Article  PubMed  Google Scholar 

  14. Japanese Ministry of Internal Affairs and Communication Statistics Bureau. Japan statistical yearbook, Chapter 2: population and households. 2016. http://www.stat.go.jp/english/. Retrieved 13 Jan 2016.

  15. Japanese Ministry of Health Labour and welfare. Vital statistics. Vital, health and social statistics division. 2014. http://www.mhlw.go.jp/toukei/list/81-1a.html. Accessed 1 April 2016.

  16. Schmidt-Erfurth U, Lang GE, Holz FG, Schlingemann RO, Lanzetta P, Massin P, et al. Three-year outcomes of individualized ranibizumab treatment in patients with diabetic macular edema: the RESTORE extension study. Ophthalmology. 2014;121:1045–53.

    Article  PubMed  Google Scholar 

  17. Heier JS, Bressler NM, Avery RL, Bakri SJ, Boyer DS, Brown DM, et al. Comparison of aflibercept, bevacizumab, and ranibizumab for treatment of diabetic macular edema: extrapolation of data to clinical practice. JAMA Ophthalmol. 2016;134:95–9.

    Article  PubMed  Google Scholar 

  18. Farouk MM, Naito T, Sayed KM, Nagasawa T, Katome T, Radwan G, et al. Outcomes of 25-gauge vitrectomy for proliferative diabetic retinopathy. Graefe’s Arch Clin Exp Ophthalmol. 2011;249:369–76.

    Article  Google Scholar 

  19. Guthrie G, Magill H, Steel DH. 23-gauge versus 25-gauge vitrectomy for proliferative diabetic retinopathy: a comparison of surgical outcomes. Ophthalmologica. 2015;233:104–11.

    Article  PubMed  Google Scholar 

  20. Neville SE, Boye KS, Montgomery WS, Iwamoto K, Okamura M, Hayes RP. Diabetes in Japan: a review of disease burden and approaches to treatment. Diabetes/Metab Res Rev. 2009;25:705–16.

    Article  Google Scholar 

  21. Iwase A, Araie M, Tomidokoro A, Yamamoto T, Shimizu H, Kitazawa Y, et al. Prevalence and causes of low vision and blindness in a Japanese adult population: the Tajimi study. Ophthalmology. 2006;113:1354–62.

    Article  PubMed  Google Scholar 

  22. Yamada M, Hiratsuka Y, Roberts CB, Pezzullo ML, Yates K, Takano S, et al. Prevalence of visual impairment in the adult Japanese population by cause and severity and future projections. Ophthalmic Epidemiol. 2010;17:50–7.

    Article  PubMed  Google Scholar 

  23. Zarbin M. Cell-based therapy for degenerative retinal disease. Trends Mol Med. 2016;22:115–34.

    Article  PubMed  Google Scholar 

  24. Rowland TJ, Buchholz DE, Clegg DO. Pluripotent human stem cells for the treatment of retinal disease. J Cell Physiol. 2012;227:457–66.

    Article  CAS  PubMed  Google Scholar 

  25. Ramsden CM, Powner MB, Carr AJ, Smart MJ, da Cruz L, Coffey PJ. Stem cells in retinal regeneration: past, present and future. Development. 2013;140:2576–85.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Bassuk AG, Zheng A, Li Y, Tsang SH, Mahajan VB. Precision medicine: genetic repair of retinitis pigmentosa in patient-derived stem cells. Sci Rep. 2016;6:19969.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Luo YH, da Cruz L. The argus((R)) II retinal prosthesis system. Prog Retinal Eye Res. 2016;50:89–107.

    Article  Google Scholar 

  28. Chow AY, Bittner AK, Pardue MT. The artificial silicon retina in retinitis pigmentosa patients (an American Ophthalmological Association thesis). Trans Am Ophthalmol Soc. 2010;108:120–54.

    PubMed  PubMed Central  Google Scholar 

  29. Bourne RR, Jonas JB, Flaxman SR, Keeffe J, Leasher J, Naidoo K, et al. Prevalence and causes of vision loss in high-income countries and in Eastern and Central Europe: 1990–2010. Br J Ophthalmol. 2014;98:629–38.

    Article  PubMed  Google Scholar 

  30. Bloch SB, Larsen M, Munch IC. Incidence of legal blindness from age-related macular degeneration in denmark: year 2000 to 2010. Am J Ophthalmol. 2012;153(209–13):e2.

    Google Scholar 

  31. World Health Organization. Blindness: magnitude and causes of visual impairment. 2016. http://www.who.int/mediacentre/factsheets/fs282/en/index.html. Accessed April 1 2016.

  32. Tanito M, Miyake T, Ohira A. The rate of official registration of legally visually handicapped patients in the handbook of the physically handicapped. Atarashii Ganka (Journal of the Eye). 2000;17:1315–8.

    Google Scholar 

  33. Hotta K, Sasho A. Shikakusyogaisya ni yoru Shintaisyogaisyatecyosyutoku no Genjyo to Kadai. Nihon no Ganka (Ophthalmic practice). 2003;74:1021–3.

    Google Scholar 

  34. Fujita A, Saito K, Ando N, Ogawa I, Abe H. Current status of registration as visually handicapped by outpatients in Niigata Prefecture. Rinsho Ganka (Jpn J Clin Ophthalmol). 1999;53:725728.

    Google Scholar 

  35. Nakamura Y, Tomidokoro A, Sawaguchi S, Sakai H, Iwase A, Araie M. Prevalence and causes of low vision and blindness in a rural Southwest Island of Japan: the Kumejima study. Ophthalmology. 2010;117:2315–21.

    Article  PubMed  Google Scholar 

Download references

Acknowledgement

We thank Professor Duco I. Hamasaki of the Bascom Palmer Eye Institute, University of Miami for critical discussion and final manuscript revisions.

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Correspondence to Kengo Ikesugi.

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The authors declare that they have no conflicts of interest.

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Ikesugi, K., Ichio, T., Tsukitome, H. et al. Annual incidences of visual impairment during 10-year period in Mie prefecture, Japan. Jpn J Ophthalmol 61, 293–298 (2017). https://doi.org/10.1007/s10384-017-0517-x

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  • DOI: https://doi.org/10.1007/s10384-017-0517-x

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