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Noninvasive diagnostics supporting system for choroidal melanoma: a pilot study

  • Clinical Investigation
  • Published:
Japanese Journal of Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To examine the usefulness of a near-infrared hyperspectral imager (NIR-HSI) system in discriminating uveal melanoma from other intraocular tumors.

Method

The NIR-HSI, which had been developed as a screening system for age-related macular degeneration, was used to measure near-infrared hyperspectral data (NIR-HSD) of a lesion located at the ocular fundus of 17 Japanese patients, including 5 with choroidal melanoma and 12 with other intraocular tumors. The index was derived from each NIR-HSD. Non-parametric statistical analysis was performed.

Results

Diagnostic accuracy of 94.1 % was achieved when the threshold value of the index was set to minimize the average value of false-positive and -negative fractions.

Conclusions

The NIR-HSI system is useful as a noninvasive diagnostic supporting system for choroidal melanoma.

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Conflicts of interest

O. Kameyama, None; Y. Usui, None; K. Kimura, None; A. Nakamura, None; T. Sota, None; H. Goto, None.

Author information

Authors and Affiliations

  1. Department of Electrical Engineering and Bioscience, Waseda University, Shinjuku, Tokyo, 169-8555, Japan

    Ori Kameyama & Takayuki Sota

  2. Department of Ophthalmology, Tokyo Medical University Hospital, Shinjuku, Tokyo, 160-0023, Japan

    Yoshihiko Usui, Keisuke Kimura & Hiroshi Goto

  3. Research Institute for Science and Engineering, Waseda University, Shinjuku, Tokyo, 169-8555, Japan

    Atsushi Nakamura & Takayuki Sota

Authors
  1. Ori Kameyama
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  2. Yoshihiko Usui
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  3. Keisuke Kimura
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  4. Atsushi Nakamura
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  5. Takayuki Sota
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  6. Hiroshi Goto
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Corresponding author

Correspondence to Yoshihiko Usui.

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Kameyama, O., Usui, Y., Kimura, K. et al. Noninvasive diagnostics supporting system for choroidal melanoma: a pilot study. Jpn J Ophthalmol 59, 48–54 (2015). https://doi.org/10.1007/s10384-014-0351-3

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  • DOI: https://doi.org/10.1007/s10384-014-0351-3

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