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Clinical features and glaucoma according to optic disc size in a South Korean population: the Namil study

Japanese Journal of Ophthalmology volume 58, pages 205–211 (2014)Cite this article

Abstract

Purpose

To assess the proportion of glaucomatous eyes based on the association between optic disc (OD) size and its clinical determinants in the resident population of Namil-myon, Central South Korea.

Methods

Of the 1,532 participants in the Namil study, we included 1,410 Koreans (2,734 eyes) with legible fundus photographs in this study. Following the estimation of OD size on the photographs using Image J software, we corrected for image magnification. Associations between the clinical features, such as age, sex, axial length (AL), spherical equivalent (SE), and central corneal thickness, and the estimated OD size were assessed for individual eyes. After adjusting for the influencing factors, the proportion of glaucoma was compared among three categories of measured OD size (small, medium, and large OD groups).

Results

After adjusting for the potential confounders using a linear mixed model, age, sex, AL, and SE were correlated with the OD size estimates (P = 0.003, P = 0.029, P < 0.001, and P < 0.001, respectively). The percentage of glaucomatous eyes was 3.77 % in the small disc group, which was higher than in the other groups (P = 0.054). In particular, normal tension glaucoma (NTG) was statistically significantly more frequent in this group (odds ratio = 1.86, P = 0.042).

Conclusions

These results suggest that clinical features such as age, sex, AL, and SE might need to be considered for an accurate evaluation of the OD. In addition, in individuals with a small OD, the presence of NTG must be carefully investigated in the South Korea population.

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Acknowledgments

This manuscript was edited for English grammar by a native writer at the Harrisco Research Institute.

Conflicts of interest

N.H. Kang, None; R.M. Jun, None; K.-R. Choi, None.

Author information

Affiliations

  1. Department of Ophthalmology, Institute of Ophthalmology and Optometry, School of Medicine, Ewha Womans University Mok-dong Hospital, 911-1 Mok-dong, Yangcheon-ku, Seoul, 158-710, Republic of Korea

    Na Hee Kang, Roo Min Jun & Kyu-Ryong Choi

  2. Korean Glaucoma Society, Seoul, Korea

    Kyu-Ryong Choi

Authors
  1. Na Hee Kang
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  2. Roo Min Jun
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  3. Kyu-Ryong Choi
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Consortia

The Namil Study group, Korean Glaucoma Society

Corresponding author

Correspondence to Kyu-Ryong Choi.

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Kang, N.H., Jun, R.M., Choi, KR. et al. Clinical features and glaucoma according to optic disc size in a South Korean population: the Namil study. Jpn J Ophthalmol 58, 205–211 (2014). https://doi.org/10.1007/s10384-014-0303-y

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  • DOI: https://doi.org/10.1007/s10384-014-0303-y

Keywords

  • Glaucoma
  • Normal tension glaucoma
  • Namil study
  • Optic disc size