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Japanese Journal of Ophthalmology

, Volume 58, Issue 2, pp 188–196 | Cite as

Paracentral scotoma in glaucoma detected by 10-2 but not by 24-2 perimetry

  • Masanori HangaiEmail author
  • Hanako Ohashi Ikeda
  • Tadamichi Akagi
  • Nagahisa Yoshimura
Clinical Investigation

Abstract

Purpose

To describe, in glaucomatous patients, spectral-domain optical coherence tomography (SD-OCT) results predictive of paracentral visual field (VF) defects present on standard automated perimetry (SAP) 10-2, but not on SAP 24-2.

Methods

The SAP 10-2 test was repeated 3 times to determine whether paracentral VF defects were present. Spectralis™ HRA + OCT was used to obtain speckle-noise-reduced macular B-scans. The macular scan protocol consisted of 19 vertical cross-sectional scan lines centered on the fovea (30° × 15° volume scan), each of which was the average of 50 scans. A 3D OCT-2000 was also used to determine macular layer thicknesses and to detect abnormally thin regions (below the 1 % confidence interval of the normative data).

Results

We identified 3 cases in which paracentral VF defects were detected on SAP 10-2, but not on SAP 24-2. Paracentral VF defects were detected on all of the SAP 10-2 tests repeated 3 times, and included absolute scotoma in 2 of the 3 SAP 10-2 results. Retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) damage was diminished on SD-OCT macular images; 2 patients had RNFL and GCL thinning within and central to the parafoveal region, where the GCL is generally thickest in healthy eyes, and 1 patient had evident RNFL and GCL thinning in the papillomacular bundle.

Conclusions

Macular SD-OCT scans may be useful in deciding whether SAP 10-2 should be performed.

Keywords

Glaucoma Paracentral scotoma Spectral-domain optical coherence tomography Visual field testing 

Notes

Acknowledgments

This research was supported in part by a Grant-in-Aid for Scientific Research (20592038) from the Japan Society for the Promotion of Science (JSPS), Tokyo, Japan.

Conflicts of interest

M. Hangai, Consultant (NIDEK, Topcon), Grants (Canon, Topcon), Lectures (Heidelberg Engineering, Santen); H. Ohashi Ikeda, None; T. Akagi, None; N. Yoshimura, Consultant (NIDEK), Grants (NIDEK, Topcon, Canon), Lectures (Topcon, Canon).

Supplementary material

10384_2013_298_MOESM1_ESM.tif (35 mb)
Supplementary material 1 (TIFF 35824 kb) Supplementary Fig. 1. Pattern deviation maps of 10-2 perimetry performed at 3 visits. A, B, C, Pattern deviation maps of 10-2 perimetry corresponding to K, L, M of the revised Fig. 2 (case 1). D, E, F, Pattern deviation maps of 10-2 perimetry corresponding to K, L, M of the revised Fig. 3 (case 2). G, H, I, Pattern deviation maps of 10-2 perimetry corresponding to M, N, O of the revised Fig. 4 (case 1)

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Copyright information

© Japanese Ophthalmological Society 2014

Authors and Affiliations

  • Masanori Hangai
    • 1
    • 2
    • 3
    Email author
  • Hanako Ohashi Ikeda
    • 1
  • Tadamichi Akagi
    • 1
  • Nagahisa Yoshimura
    • 1
  1. 1.Department of Ophthalmology and Visual SciencesKyoto University Graduate School of MedicineKyotoJapan
  2. 2.Department of OphthalmologyKurume University School of MedicineKurumeJapan
  3. 3.Department of OphthalmologySaitama Medical UniversityIrumaJapan

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