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Effect of myopia and age on optic disc margin anatomy within the parapapillary atrophy area

Japanese Journal of Ophthalmology volume 57, pages 463–470 (2013)Cite this article

Abstract

Purpose

To evaluate the effect of myopia and age on temporal optic disc margin anatomy within the parapapillary atrophy (PPA) area by use of spectral-domain optical coherence tomography (OCT).

Methods

Fifty young myopic eyes with PPA (myopic PPA group), 50 aged non-myopic eyes with PPA (aged PPA group), and 50 young non-myopic eyes without PPA (control group) were enrolled. High-definition OCT scanning was used to obtain horizontal cross-sectional optic nerve head (ONH) images. By use of these OCT scans we investigated three temporal optic disc margin structures: the configuration of the border tissue of Elschnig; the cross-sectional ONH structure coinciding with the clinically detected optic disc margin; and the integrity of the retinal layers within the PPA area.

Results

The distribution of the configuration of the border tissue of Elschnig and the cross-sectional ONH structure coinciding with the clinically detected optic disc margin of the myopic PPA group differed significantly from those of the control group (P < 0.01) whereas those of the aged PPA group did not (P > 0.05). Other than the photoreceptor layer, the retinal layers within the PPA area were more commonly impaired in the myopic PPA group than in the aged PPA group (P < 0.001).

Conclusions

Myopia and aging led to different structural changes in temporal optic disc margin anatomy within the PPA area. This finding implies that different mechanisms may underlie myopic and age-related PPA development.

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Affiliations

  1. Department of Ophthalmology, Kim’s Eye Hospital, Myung-Gok Eye Research Institute, Konyang University, #156 Youngdeungpo-dong 4ga, Youngdeungpo-gu, Seoul, 150-034, Korea

    Young Hoon Hwang & Jong Jin Jung

  2. Department of Ophthalmology, Armed Forces Capital Hospital, Seongnam, Korea

    Young Min Park

  3. Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea

    Yong Yeon Kim

  4. Balgeunsesang Eye Clinic, Seoul, Korea

    Sungwook Woo

  5. Department of Ophthalmology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea

    Joo Hwa Lee

Authors
  1. Young Hoon Hwang
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  2. Jong Jin Jung
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  3. Young Min Park
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  4. Yong Yeon Kim
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  5. Sungwook Woo
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  6. Joo Hwa Lee
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Correspondence to Young Hoon Hwang.

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Hwang, Y.H., Jung, J.J., Park, Y.M. et al. Effect of myopia and age on optic disc margin anatomy within the parapapillary atrophy area. Jpn J Ophthalmol 57, 463–470 (2013). https://doi.org/10.1007/s10384-013-0263-7

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  • DOI: https://doi.org/10.1007/s10384-013-0263-7

Keywords

  • Age
  • Glaucoma
  • Myopia
  • Optical coherence tomography
  • Parapapillary atrophy