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Three different aspheric treatment algorithms of laser-assisted sub-epithelial keratectomy in patients with high myopia

  • Clinical Investigation
  • Published:
Japanese Journal of Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To compare visual outcomes and quality in high myopia patients treated using one of three aspheric treatment algorithms based on the NIDEK Advanced Vision Excimer Laser System.

Methods

Sixty eyes of 60 high myopia patients (>−6 diopter) underwent topography-guided (CATz) (20 eyes), wavefront-guided (OPDCAT) (20 eyes), or topography and wavefront-guided (OPA) (20 eyes) laser-assisted sub-epithelial keratectomy. Visual acuity, manifest refraction spherical equivalent (MRSE), ocular and corneal higher order aberrations, corneal asphericity, point spread function (Strehl ratio) and modulation transfer function (MTF) were compared preoperatively and 1, 3 and 6 months postoperatively.

Results

Six months after surgery, logMAR uncorrected visual acuity was 0.02 ± 0.09 in the CATz group, 0.02 ± 0.07 in the OPDCAT group and 0.02 ± 0.08 in the OPA group, and there were no statistically significant differences (P = 0.5355). No statistical differences were found among the three groups in MRSE (P = 0.3541). Induced spherical aberrations and the change of corneal asphericity were less in the OPA group than in the others (P < 0.0001). The MTF was slightly better in the OPA group than in the others. The Strehl ratio showed no statistically significant differences among the three groups.

Conclusions

All three aspheric treatment algorithms were safe and effective in correcting high myopia. Among them, the OPA algorithm maintained optical quality and physiologic cornea longer than the others.

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Acknowledgments

We would like to acknowledge Yura Shin from Hankuk Academy of Foreign Studies for her help with analysis of the clinical data and the correction of English in the study. This study was supported by grant MEST (supported in part by grant MEST 2010-0022006) from the National Research Foundation of Korea and the Converging Research Center Program funded by the Ministry of Education, Science and Technology (2012K001354).

Conflict of interest

None of the authors has any financial/conflicting interests to disclose.

Author information

Authors and Affiliations

  1. Siloam Eye Hospital, Seoul, Korea

    Ji Min Ahn

  2. Lee Eye Clinic, 1124-11, Yeonsan-5-dong, Yeonje-gu, Busan, Korea

    Bong Joon Choi

  3. Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Korea

    Eung Kweon Kim, Bradford Sgrignoli & Tae-im Kim

  4. Department of Ophthalmology, Cornea Dystrophy Research Institute, Yonsei University College of Medicine, Seoul, Korea

    Eung Kweon Kim

  5. Severance Biomedical Science Institute, and Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea

    Eung Kweon Kim

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  1. Ji Min Ahn
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  2. Bong Joon Choi
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  3. Eung Kweon Kim
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Correspondence to Tae-im Kim.

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Ahn, J.M., Choi, B.J., Kim, E.K. et al. Three different aspheric treatment algorithms of laser-assisted sub-epithelial keratectomy in patients with high myopia. Jpn J Ophthalmol 57, 191–198 (2013). https://doi.org/10.1007/s10384-012-0218-4

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  • DOI: https://doi.org/10.1007/s10384-012-0218-4

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