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Relationship between macular ganglion cell complex parameters and visual field parameters after tumor resection in chiasmal compression

Japanese Journal of Ophthalmology volume 56, pages 68–75 (2012)Cite this article

Abstract

Purpose

To evaluate the relationship between macular ganglion cell complex (GCC) parameters and visual field (VF) parameters in chiasmal compression and the potential for GCC parameters in order to predict the short-term post-surgical VF.

Methods

Twenty-three eyes of 12 patients with chiasmal compression and 33 control eyes were studied. All patients underwent transsphenoidal tumor resection. Before surgery a 3D scan of the macula was taken using spectral-domain optical coherence tomography. All patients underwent Humphrey 24-2 VF testing after surgery. Spearman’s rank correlation coefficients were used to evaluate the relationship between the GCC parameters and VF parameters [mean deviation (MD), pattern standard deviation]. Coefficients of determination (R 2) were calculated using linear regression.

Results

Average thickness in the patients was significantly thinner than that of controls. Average thickness, global loss volume and focal loss volume (FLV) significantly correlated with the MD. We observed the greatest R 2 between FLV and MD.

Conclusions

Examining the macular GCC was useful for evaluating structural damage in patients with chiasmal compression. Preoperative GCC parameters, especially FLV, may be useful in predicting visual function following surgical decompression of chiasmal compression.

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Acknowledgments

We thank JAM Post editing for this manuscript.

Conflict of interest

The authors have no proprietary interests in any of the material used in this study.

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Affiliations

  1. Department of Ophthalmology and Visual Science, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, 920-8641, Japan

    Shinji Ohkubo, Tomomi Higashide, Hisashi Takeda, Eiji Murotani & Kazuhisa Sugiyama

  2. Department of Neurosurgery, Division of Neuroscience, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan

    Yasuhiko Hayashi

Authors
  1. Shinji Ohkubo
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  2. Tomomi Higashide
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  3. Hisashi Takeda
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  4. Eiji Murotani
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  5. Yasuhiko Hayashi
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  6. Kazuhisa Sugiyama
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Corresponding author

Correspondence to Shinji Ohkubo.

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Cite this article

Ohkubo, S., Higashide, T., Takeda, H. et al. Relationship between macular ganglion cell complex parameters and visual field parameters after tumor resection in chiasmal compression. Jpn J Ophthalmol 56, 68–75 (2012). https://doi.org/10.1007/s10384-011-0093-4

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  • DOI: https://doi.org/10.1007/s10384-011-0093-4

Keywords

  • Chiasmal compression
  • Focal loss volume
  • Ganglion cell complex
  • Optical coherence tomography
  • Visual field