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Relationship between vision-related quality of life and microperimetry-determined macular sensitivity in patients with retinitis pigmentosa

Japanese Journal of Ophthalmology volume 55, pages 643–646 (2011)Cite this article

Abstract

Purpose

The aim of our study was to determine the relationship between vision-related quality of life (VRQOL) following the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25) and the macular sensitivity determined by microperimetry in patients with retinitis pigmentosa (RP).

Methods

The Japanese version of the NEI VFQ-25 was used to assess the VRQOL of 30 patients with typical RP whose decimal visual acuity was ≥0.6. The mean retinal sensitivity within the central 10° was determined by fundus-related microperimetry (MP1). The correlation between the mean of the total composite NEI VFQ-25 score and MP1-determined macular sensitivity was determined.

Results

Mean NEI VFQ-25 score was 69.4 ± 14.5 (range 34.6–90.3) in RP patients. There was a significant positive correlation between mean NEI VFQ-25 score and mean retinal sensitivity within 10° (r = 0.673, P = 0.0003).

Conclusion

The significant correlation between macular sensitivity and VRQOL measured with the NEI VFQ-25 indicates that sensitivity in the macular area is an important consideration in using VRQOL with RP patients.

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Affiliations

  1. Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8670, Japan

    Takeshi Sugawara, Eiju Sato, Takayuki Baba, Akira Hagiwara, Ayako Tawada & Shuichi Yamamoto

Authors
  1. Takeshi Sugawara
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  2. Eiju Sato
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  3. Takayuki Baba
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  4. Akira Hagiwara
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  5. Ayako Tawada
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  6. Shuichi Yamamoto
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Corresponding author

Correspondence to Takeshi Sugawara.

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Cite this article

Sugawara, T., Sato, E., Baba, T. et al. Relationship between vision-related quality of life and microperimetry-determined macular sensitivity in patients with retinitis pigmentosa. Jpn J Ophthalmol 55, 643–646 (2011). https://doi.org/10.1007/s10384-011-0080-9

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  • DOI: https://doi.org/10.1007/s10384-011-0080-9

Keywords

  • Retinitis pigmentosa
  • Vision-related quality of life
  • NEI VFQ-25
  • Fundus-related microperimetry
  • Macular sensitivity