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Pars Plana Vitrectomy with Removal of Posterior Hyaloid Face in Treatment of Refractory Diabetic Macular Edema Resistant to Triamcinolone Acetonide

Japanese Journal of Ophthalmology volume 50, pages 529–531 (2006)Cite this article

Abstract

Background

Triamcinolone acetonide (TA) has recently been used to treat diabetic macular edema (DME) but its effectiveness is limited.

Cases

Three patients (three eyes) with unresolved diffuse DME who did not respond to a posterior sub-Tenon's injection of TA underwent vitrectomy.

Observations

Intraoperatively, it was found that all of the eyes had a posterior hyaloid face that was adherent to a large area of the posterior pole retina, although this had not been detected by slit-lamp biomicroscopy or optical coherence tomography. After vitrectomy and removal of the posterior hyaloid face, there was a significant reduction in the central macular thickness of all three eyes and an improvement in the visual acuity of the patients.

Conclusions

When TA treatment is not effective for DME, vitrectomy with the complete removal of the posterior hyaloid face, including removal of the internal limiting membrane, should be considered.

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Author information

Affiliations

  1. Department of Ophthalmology, Kansai Medical University, Moriguchi, Osaka, Japan

    Akiko Higuchi, Nahoko Ogata, Nobuo Jo, Mitsumasa Wada & Miyo Matsumura

Authors
  1. Akiko Higuchi
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  2. Nahoko Ogata
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  3. Nobuo Jo
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  4. Mitsumasa Wada
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  5. Miyo Matsumura
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Corresponding author

Correspondence to Nahoko Ogata.

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Cite this article

Higuchi, A., Ogata, N., Jo, N. et al. Pars Plana Vitrectomy with Removal of Posterior Hyaloid Face in Treatment of Refractory Diabetic Macular Edema Resistant to Triamcinolone Acetonide. Jpn J Ophthalmol 50, 529–531 (2006). https://doi.org/10.1007/s10384-006-0366-5

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  • DOI: https://doi.org/10.1007/s10384-006-0366-5

Key words

  • diabetic macular edema
  • diabetic retinopathy
  • optical coherence tomography
  • triamcinolone acetonide
  • vitrectomy