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Hydrogen peroxide (H2O2): a review of its use in surgery

Wasserstoffperoxid (H2O2) – eine Übersicht zur Verwendung in der Chirurgie

Summary

Hydrogen peroxide has been used in medicine for more than 100 years. It is known in surgery as a highly useful irrigation solution by virtue of both its hemostatic and its antimicrobial effects. Due to its possible negative effect on wound healing and its cytotoxic effect in higher concentrations, there are concerns about the safety of its use. The objective of this paper is to review the safety and beneficial effects of hydrogen peroxide.

Zusammenfassung

Wasserstoffperoxid wird in der Medizin seit über 100 Jahren benutzt. In der Chirurgie wird es wegen seiner hämostatischen und antimikrobiellen Wirkung als Spüllösung verwendet. Aufgrund der möglichen negativen Auswirkungen auf die Wundheilung und wegen der Zytotoxizität in höheren Konzentrationen gibt es Bedenken in Bezug auf die Sicherheit der Nutzung. Im vorliegenden Beitrag sollen die Sicherheit und die positiven Wirkungen von Wasserstoffperoxid überprüft werden.

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Correspondence to Michael Vincent Urban.

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M.V. Urban, T. Rath, and C. Radtke declare that they have no competing interests.

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Urban, M.V., Rath, T. & Radtke, C. Hydrogen peroxide (H2O2): a review of its use in surgery. Wien Med Wochenschr 169, 222–225 (2019). https://doi.org/10.1007/s10354-017-0610-2

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Keywords

  • Hydrogen peroxide
  • Irrigation solution
  • Cytotoxicity
  • Antimicrobial
  • Wound healing

Schlüsselwörter

  • Wasserstoffperoxid
  • Spüllösung
  • Zytotoxizität
  • Antimikrobiell
  • Wundheilung