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Two-question depression-screeners – the solution to all problems?

Zwei-Fragen-Depressions-Screener – die Lösung aller Probleme?

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Zusammenfassung

Depression ist bereits heute epidemiologisch eine beachtenswerte Größe in der Medizin. Voraussichtlich wird die Zahl der Patienten, die an einer Depression leiden, zukünftig noch deutlich zunehmen. Ein einfaches, schnelles Screening zur Entdeckung von Depressiven wäre deshalb hilfreich. In letzter Zeit wurden vier Artikel publiziert, die jeweils einen Zwei-Fragen-Screener empfehlen. METHODE: Es werden die Sensitivität, Spezifität, Likelihood Ratios, negative und positive Vorhersagewerte der Screener verglichen. ERGEBNISSE: Die Prävalenz für Depression reichte in vier klinischen und einer bevölkerungsrepräsentativen (Deutschland) Stichprobe von 6.9 % bis 18.1 %. Sensitivität und Spezifität erreichten Werte zwischen 72.6 % und 96.6 % beziehungsweise zwischen 56.9 % und 90.0 %. Gegenüber den positiven Vorhersagewerten (17.8 % bis 38.5 %) waren alle negativen Vorhersagewerte hoch (< 97 %). SCHLUSSFOLGERUNG: Alles in allem scheinen Zwei-Fragen-Screener gut geeignet, Major Depression auszuschließen. Möglicherweise kann routinemäßiges Screening die Anzahl der Fälle nicht diagnostizierter Depression mindern.

Summary

Depression constitutes a considerable issue in medicine and it is anticipated that the amount of people suffering from affective disorders will increase significantly. It would be useful to have a simple, fast screening procedure which would help detect depression. In four recently published articles a two-question depression-screener is recommended. METHOD: Sensitivity, specificity, likelihood ratios, negative and positive predictive values were compared. RESULTS: For four different clinical samples and one sample that was representative of the German population the prevalence for depression ranged from 6.9 % to 18.1 %. Sensitivity and specificity reached values from 72.6 % to 96.6 % and from 56.9 % to 90.0 % respectively. All negative predictive values were high (< 97 %) opposed to positive predictive values (17.8 % to 38.5 %). CONCLUSION: Overall, it seems that the two-question screenings are well suited for the exclusion of a major depression. It is possible that regular screening could further lower the percentage of undiagnosed cases.

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References

  • Andlin-Sobocki P, Jönsson B, Wittchen H, Oelsen J (2005) Cost of disorders of the brain in Europe. Eur J Neurol 12: 1–27

    Article  PubMed  Google Scholar 

  • Ustun T, Ayuso-Mateos J, Chatterji S, Meathers C, Murray C (2004) Global burden of depressive disorders in the community and in primary care: the size and the breadth of the problem. Br J Psychiatry 184: 386–392

    Article  PubMed  CAS  Google Scholar 

  • Wittchen HU, Höfler M, Meister W (2000) Depression in der Allgemeinarztpraxis. Die bundesweite Depressionsstudie. Schattauer, Stuttgart

    Google Scholar 

  • U. S. Preventive Services Task Force (2002) Screening for depression: recommendations and rationale. Ann Intern Med 136: 760–776

    Google Scholar 

  • Kroenke K, Spitzer RL, Williams JBW (2003) The Patient Health Questionnaire-2. Validity of a two-item depression screener. Med Care 41: 1284–1292

    Article  PubMed  Google Scholar 

  • Grulke N, Bailer H, Blaser G, Geyer M, Hinz A, Schmutzer G et al. (2005) Depressivitäts-Screening – zwei Fragen für die Praxis. Wien Med Wochenschr 155: 297–302

    Article  PubMed  Google Scholar 

  • Arroll B, Khin N, Kerse N (2003) Screening for depression in primary care with two verbally asked questions: cross sectional study. Br Med J 327: 1144–1146

    Article  Google Scholar 

  • Löwe B, Kroenke K, Gräfe K (2005) Detecting and monitoring depression with a two-item questionnaire (PHQ-2). J Psychosom Res 58: 163–171

    Article  PubMed  Google Scholar 

  • Whooley MA, Avins AL, Miranda J, Browner W (1997) Case-finding instruments for depression. Two questions are as good as many. J Gen Intern Med 12: 439–445

    Article  PubMed  CAS  Google Scholar 

  • Sackett DL, Richardson WS, Rosenberg W, Haynes RB (1997) Evidence-based medicine: How to practice and teach EBM. Churchill Livingstone, New York Edinburgh London

    Google Scholar 

  • Porzsolt F, Richter C, Ehrenstein T, Sehouli J, Camara O, Glaubitz R et al. (2000) Was ist unter "Likelihood ratio" zu verstehen? Evid Based Med (German) 4: 7–8

    Google Scholar 

  • Kessler D, Bennewith O, Lewis G, Sharp D (2002) Detection of depression and anxiety in primary care: follow up study. Br Med J 325: 1016–1017

    Article  Google Scholar 

Download references

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Correspondence to Norbert Grulke.

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Albani, C., Bailer, H., Blaser, G. et al. Two-question depression-screeners – the solution to all problems?. Wien Med Wochenschr 156, 185–188 (2006). https://doi.org/10.1007/s10354-006-0274-9

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  • DOI: https://doi.org/10.1007/s10354-006-0274-9

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