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Littoral cell angioma of the spleen: case report and literature review

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Summary

Background

Littoral cell angioma (LCA) is a rare vascular tumor of the spleen which is usually benign and sometimes associated with other malignancies. The diagnosis of LCA is based on histopathological examination with specific immunohistochemical stainings.

Material and methods

We report a case of LCA 40-year-old male patient.

Results

The patient admitted with nonspecific left upper abdominal pain and identified splenomegaly and nodular splenic lesion by abdominal ultrasonography and magnetic resonance imaging. Splenectomy was performed, and tumor cells were stained diffusely with factor 8 and CD68, focally with S-100 in the immunohistochemical examination. The vascular structures of the lesion were stained with CD34 without CD31.

Conclusions

Long-term follow-up for suspicious malignant potential is advised.

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Fig. 1
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Author information

Authors and Affiliations

  1. Department of General Surgery, Bozyaka Training and research Hospital, Izmir, Turkey

    O. B. Namdaroglu MD

  2. Department of General Surgery, Kayseri Training and Research Hospital, Kayseri, Turkey

    Y. Sevim MD

  3. Department of General Surgery, Ankara Medicana International Hospital, Ankara, Turkey

    O. Yildirim MD

  4. Department of Pathology, Ankara Numune Training and Research Hospital, Ankara, Turkey

    E. Ozhamam MD

  5. Department of General Surgery, Sakarya University School of Medicine, Sakarya, Turkey

    B. Kocer

Authors
  1. O. B. Namdaroglu MD
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  2. Y. Sevim MD
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  3. O. Yildirim MD
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  4. E. Ozhamam MD
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  5. B. Kocer
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Corresponding author

Correspondence to Y. Sevim MD.

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Namdaroglu, O., Sevim, Y., Yildirim, O. et al. Littoral cell angioma of the spleen: case report and literature review. Eur Surg 47, 210–213 (2015). https://doi.org/10.1007/s10353-015-0332-x

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  • DOI: https://doi.org/10.1007/s10353-015-0332-x

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