Skip to main content
Log in

Idiopathic granulomatosis mastitis treated with topical steroids: case report

  • Case Report
  • Published:
European Surgery Aims and scope Submit manuscript

Summary

Background

Idiopathic granulomatous mastitis (IGM) is a rare, benign and chronic inflammatory condition of the breast. Clinically, it can mimic inflammatory breast cancer and is difficult to distinguish from tuberculous mastitis and sarcoidosis. Diagnosis of IGM is usually by exclusion and confirmed by histopathological examination.

The mainstays of treatment described in current literature are antibiotics, systemic steroids and immunosuppressants.

Case report

We present a case of IMG treated with topical steroids only, with no side effects or relapse.

Results and Conclusions

Till now, there are no specific guidelines for the management of idiopathic granulomatous mastitis. It varies from expectant management, steroid treatment till surgical intervention. Topical steroids were used as alternative to systemic preparations with the potential benefit of avoiding the side effects of long-term systemic steroid therapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Kessler E, Wolloch Y. Granulomatosis mastitis: a lesion clinically simulating carcinoma. Am J Clin Pathol. 1972;58:642–6.

    PubMed  CAS  Google Scholar 

  2. Azlina AF, Ariza Z, Arni T, Hisham AN. Chronic glaucomatous mastitis: diagnostic and therapeutic considerations. World J Surg. 2003;27:515–8.

    Article  PubMed  Google Scholar 

  3. Al-Khaffaf B, Knox F, Bundred NJ. Idiopathic granulomatous mastitis: a 25 year experience. J Am Coll Surg. 2008;206:269–73.

    Article  PubMed  Google Scholar 

  4. Akcan A, Akynndiz H, Deneme M, et al. Granulomatous lobular mastitis: a complex diagnostic and therapeutic problem. World J Surg. 2006;30:1403–9.

    Article  PubMed  Google Scholar 

  5. Fletcher A, Magrath IM, Riddle RH, Talbot IC. Granulomatous mastitis: a report of seven cases. J Clin Pathol. 1982;35:941–5.

    Article  PubMed  CAS  Google Scholar 

  6. Fu-Hsiung S, Liu SC, Suen JH, et al. Idiopathic granulomatous mastitis: a case successfully treated with a minimum dose of steroid. Chang Gung Med J. 2005;28:431–4.

    Google Scholar 

  7. Taylor GB, Paviour SD, Musaad S, et al. A clinicopathological review of 34 cases of inflammatory breast disease showing an association between corynebacteria infection and granulomatous mastitis. Pathology. 2003;35:109–19.

    PubMed  Google Scholar 

  8. Dehertogh DA, Rossof AH, Harris AA, Economou SG. Prednisolone management of granulomatous mastitis. NEJM. 1980;308:799–800.

    Article  Google Scholar 

  9. Raj N, Macmillan RD, Ellis IO, Deighton CM. Rheumatologists and breasts: immunosuppressive therapy for granulomatous mastitis. Rheumatology. 2004;43:1055–63.

    Article  PubMed  CAS  Google Scholar 

  10. Kubita K, Lo ES, Huttinot G, Anderson PH, Maibach HI. Plasma concentration after topical application of Betamethasone 17-valerate: comparison with oral administration. Br J Clin Pharmacol. 1994;37:86–8.

    Article  Google Scholar 

Download references

Conflict of interest

The authors declare that they have no competing interests.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to S. Monib.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Monib, S., Hassan, A. & Lai, L. Idiopathic granulomatosis mastitis treated with topical steroids: case report. Eur Surg 44, 354–357 (2012). https://doi.org/10.1007/s10353-012-0155-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10353-012-0155-y

Keywords

Navigation