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Preoperative and Postoperative Quality of Life in Patients with Familial Adenomatous Polyposis

  • Original Contribution
  • Published:
Diseases of the Colon & Rectum

Abstract

Purpose

This study was designed to prospectively examine functional outcome, quality of life, and patients’ personal experiences and adjustment to functional changes during the first year after prophylactic surgery.

Methods

Twenty-one consecutive patients with familial adenomatous polyposis were examined before proctocolectomy (T0), on ileostomy reversal (T1), and 6 (T2) and 12 months (T3) after surgery by means of standardized questionnaires and interviews.

Results

Average physical and mental health declined profoundly after proctocolectomy, followed by a steady improvement after 6 and 12 months. The majority of patients reported the ileostomy period as particularly distressing. After one year, 75 percent of patients reported complete recovery in terms of physical, emotional, and social functioning, whereas one-quarter of patients did not regain their former level of functioning. Despite substantial improvement in pouch functions, functional impairment persists because of frequent bowel movements, resulting mainly in restricted social activities. Ten percent of patients reported impaired sex life, irrespective of gender.

Conclusions

The majority of patients with familial adenomatous polyposis were found to adjust favorably to functional impairment while maintaining satisfactory quality of life. Complementing standardized quality of life measures by patients’ personal experiences may help to identify vulnerable patients in need of psychosocial support.

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Author information

Authors and Affiliations

  1. Department of Psychiatry, University of Ulm, Leimgrubenweg 12-14, 89075, Ulm, Germany

    Nadine Osterfeld M.D.

  2. Division of Psychooncology, Department of Psychosomatic and Clinical Medicine, University of Heidelberg, Heidelberg, Germany

    Anette Brechtel Dipl. Psych. & Monika Keller M.D.

  3. Department of Visceral and General Surgery, University of Heidelberg, Heidelberg, Germany

    Martina Kadmon M.D.

Authors
  1. Nadine Osterfeld M.D.
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  2. Martina Kadmon M.D.
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  3. Anette Brechtel Dipl. Psych.
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  4. Monika Keller M.D.
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Correspondence to Nadine Osterfeld M.D..

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Osterfeld, N., Kadmon, M., Brechtel, A. et al. Preoperative and Postoperative Quality of Life in Patients with Familial Adenomatous Polyposis. Dis Colon Rectum 51, 1324–1330 (2008). https://doi.org/10.1007/s10350-008-9383-4

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  • DOI: https://doi.org/10.1007/s10350-008-9383-4

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