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Long-Term Survival in Patients with Locally Advanced Colon Cancer After En Bloc Pancreaticoduodenectomy and Colectomy

  • Original Contribution
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Diseases of the Colon & Rectum

Abstract

Purpose

Surgical indications for colon cancer directly invading the pancreas head are controversial.

Methods

Between 1957 and 2007, a total of 12 patients (8 men) underwent pancreaticoduodenectomy combined with right hemicolectomy for colon cancer involving the pancreas head.

Results

Mean age was 58 (range, 34–77) years. Fistula formation was observed in five patients (41 percent) preoperatively. Tumor involvement was duodenum only (n = 4), duodenum/pancreas (n = 3), stomach/pancreas (n = 1), duodenum/stomach (n = 2), duodenum/liver (n = 1), and pancreas only (n = 1). Only one postoperative death was encountered. Histologic examination showed malignant invasion to the pancreas head in nine cases (75 percent). Overall one-year, three-year and, five-year survival rates after surgery were 75, 66, and 55 percent, respectively. Five patients (41 percent) survived for more than ten 10 years.

Conclusions

Pancreaticoduodenectomy for advanced colon cancer invading the pancreas or duodenum provides favorable long-term survival.

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Author information

Authors and Affiliations

  1. Department of Gastroenterological Surgery, Cancer Institute Hospital, Tokyo, Japan

    Akio Saiura M.D., Junji Yamamoto M.D., Masashi Ueno M.D., Rintaro Koga M.D. & Makoto Seki M.D.

  2. Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan

    Norihiro Kokudo M.D.

Authors
  1. Akio Saiura M.D.
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  2. Junji Yamamoto M.D.
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  3. Masashi Ueno M.D.
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  4. Rintaro Koga M.D.
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  5. Makoto Seki M.D.
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  6. Norihiro Kokudo M.D.
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Corresponding author

Correspondence to Akio Saiura M.D..

Additional information

Supported by a Grant-in-Aid for Basic Research to Dr. Akio Saiura from the Ministry of Education, Culture, Sports, Science and Technology.

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Saiura, A., Yamamoto, J., Ueno, M. et al. Long-Term Survival in Patients with Locally Advanced Colon Cancer After En Bloc Pancreaticoduodenectomy and Colectomy. Dis Colon Rectum 51, 1548–1551 (2008). https://doi.org/10.1007/s10350-008-9318-0

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  • DOI: https://doi.org/10.1007/s10350-008-9318-0

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