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A Metal Organic Framework + Ionic Liquid Pseudophase System as a Gas Chromatography Stationary Phase

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Abstract

Ionic liquids (ILs) containing colloidal metal organic frameworks (MOFs) have been used as gas chromatography stationary phases to provide distinct separation properties. The behavior of four different organic frameworks in 18 ionic liquids was investigated. Metal organic frameworks flocculated, degraded, or formed colloidal dispersions in ionic liquids. The newly developed stationary phase consisted of colloidal ZIF-8 uniformly dispersed in an imidazolium-based dicationic ionic liquid which provided the first separation of permanent gases via hybrid gas–liquid chromatography. In addition, various groups of alkanes, ketones, alcohols, ethers, and Rohrschneider-McReynolds compounds were separated on this newly developed hybrid stationary phase. Equations for the three-phase model were derived to determine the behavior of solutes with this pseudophase system. Using this model, the distribution constants between all three phases were calculated. It was shown that the metal organic framework had a significant effect on solute partitioning to the stationary phase.

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Data availability

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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Acknowledgements

We thank Leonard M. Sidisky (Millipore Sigma) for coating the 30m capillary columns. We appreciate Enas Yousef for taking the digital microscope photos.

Funding

Support of this work by the Robert A. Welch (Y-0026) Foundation is gratefully acknowledged.

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Authors and Affiliations

  1. Department of Chemistry and Biochemistry, University of Arlington, 700 Planetarium Place, Arlington, TX, 76019, USA

    Arzoo Patel, Saba Aslani, Sepideh Khaki Firooz & Daniel W. Armstrong

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  1. Arzoo Patel
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  2. Saba Aslani
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  3. Sepideh Khaki Firooz
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  4. Daniel W. Armstrong
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Contributions

AP: wrote the original draft, carried out GC and synthesis experimentation, and did the formal analysis as well as visualizations. SA carried out GC: and synthesis experiments. Contributed to data analysis and visualizations and writing the introduction and materials and methods. SKF: carried out GC experiments. DWA: conceptualized the project, proposed the methodology, supervised the project, acquired funding, reviewed, and edited the manuscript.

Corresponding author

Correspondence to Daniel W. Armstrong.

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Patel, A., Aslani, S., Firooz, S.K. et al. A Metal Organic Framework + Ionic Liquid Pseudophase System as a Gas Chromatography Stationary Phase. Chromatographia 86, 415–424 (2023). https://doi.org/10.1007/s10337-023-04258-z

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