A New Stationary Phase for Capillary Gas Chromatography: Calix[4]resorcinarene Functionalized with Imidazolium Cationic Units

Abstract

In this work, a novel calix[4]resorcinarene-based ionic liquid (C4RA-2IL) was synthesized, structurally characterized, and statically coated on capillary column as stationary phase for capillary gas chromatography (GC). The column efficiency of the C4RA-2IL column is 3345 plates m−1, which are determined by n-dodecane at 120 °C. Based on its McReynolds constants, the C4RA-2IL column showed moderate polarity. Particularly, the C4RA-2IL column show high separation performance for a wide range of analytes and some difficult separation of meta/para-isomers. Moreover, it exhibited excellent selectivity for critical aromatic isomers of chloroaniline, bromaniline, iodoaniline, toluidine and xylidine isomers and shows advantageous separation capability over the commercial polysiloxane stationary phase. This work presents a promising future of calixarene-based ionic liquid as a new type of stationary phase in GC separations.

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Acknowledgements

The work was supported by the National Natural Science Foundation of China (No. 21705072), Natural Science Foundation of Liaoning Province (20180550016), Scientific Research Fund Liaoning Provincial Education Department of China (LJGD2020015), Henan Province Science and Technology Attack Plan Foundation (No. 202102310485).

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Correspondence to Zhiqiang Cai or Tao Sun.

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Shuai, X., Cai, Z., Zhao, X. et al. A New Stationary Phase for Capillary Gas Chromatography: Calix[4]resorcinarene Functionalized with Imidazolium Cationic Units. Chromatographia 84, 325–333 (2021). https://doi.org/10.1007/s10337-021-04018-x

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Keywords

  • Calix[4]resorcinarene
  • Ionic liquid
  • Gas chromatography
  • Stationary phase
  • Aromatic isomers