Skip to main content
Log in

Comparative analysis of SINC-shaped and SLR pulses performance for contiguous multi-slice fast spin-echo imaging using metamaterial-based MRI

  • Research Article
  • Published:
Magnetic Resonance Materials in Physics, Biology and Medicine Aims and scope Submit manuscript

Abstract

Objective

To comparatively assess the performance of highly selective pulses computed with the SLR algorithm in fast-spin echo (FSE) within the current radiofrequency safety limits using a metamaterial-based coil for wrist magnetic resonance imaging.

Methods

Apodized SINC pulses commonly used for clinical FSE sequences were considered as a reference. Selective SLR pulses with a time-bandwidth product of four were constructed in the MATPULSE program. Slice selection profiles in conventional T1-weighted and PD-weighted FSE wrist imaging pulse sequences were modeled using a Bloch equations simulator. Signal evolution was assessed in three samples with relaxation times equivalent to those in musculoskeletal tissues at 1.5T. Regular and SLR-based FSE pulse sequences were tested in a phantom experiment in a multi-slice mode with different gaps between slices and the direct saturation effect was investigated.

Results

As compared to the regular FSEs with a conventional transmit coil, combining the utilization of the metadevice with SLR-based FSEs provided a 23 times lower energy deposition in a duty cycle. When the slice gap was decreased from 100 to 0%, the “slice cross-talk” effect reduced the signal intensity by 15.9–17.6% in the SLR-based and by 22.9–32.3% in the regular T1-weighted FSE; and by 0.0–6.4% in the SLR-based and by 0.3–9.3% in the regular PD-weighted FSE.

Discussion and conclusion

SLR-based FSE together with the metadevice allowed to increase the slice selectivity while still being within the safe SAR limits. The “slice cross-talk” effects were conditioned by the number of echoes in the echo train, the repetition time, and T1 relaxation times. The approach was more beneficial for T1-weighted SLR-based FSE as compared to PD-weighted. The combination of the metadevice and SLR-based FSE offers a promising alternative for MR investigations that require scanning in a “Low-SAR” regime such as those for children, pregnant women, and patients with implanted devices.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Radu X, Dardenne X, Craeye C (2007) Experimental results and discussion of imaging with a wire medium for MRI imaging applications. In: IEEE Antennas and Propagation Society, AP-S International Symposium (Digest) 4396793:5499–5502

  2. Motovilova E, Sandeep S, Hashimoto M, Huang SY (2019) Water-tunable highly sub-wavelength spiral resonator for magnetic field enhancement of MRI coils at 1.5 T. IEEE Access 7:90304–90315

    Article  Google Scholar 

  3. Brui EA, Shchelokova AV, Zubkov M, Melchakova IV, Glybovskiy SB, Slobozhanyuk AP (2018) Adjustable subwavelength metasurface for magnetic resonance imaging. Phys Status Solidi A 215:1700788

    Article  Google Scholar 

  4. Shchelokova AV, Dobrykh DA, Glybovski SB et al (2018) Volumetric wireless coil based on periodically coupled split-loop resonators for clinical wrist imaging. Magn Reson Med 80:1726–1737

    Article  Google Scholar 

  5. Schmidt R, Slobozhanyuk A, Belov P, Webb A (2017) Flexible and compact hybrid metasurfaces for enhanced ultra high field in vivo magnetic resonance imaging. Sci Rep 7:1678

    Article  Google Scholar 

  6. Ladd M, Bachert P, Meyerspeer M, Moser E, Nagel AM, Norris DG, Schmitter S, Speck O, Straub S, Zaiss M (2018) Pros and cons of ultra-high-field MRI/MRS for human application. Prog Nucl Magn Reson Spectrosc 109:1–50

    Article  CAS  Google Scholar 

  7. Kim D, Oesingmann N, McGorty K (2009) Hybrid adiabatic-rectangular pulse train for effective saturation of magnetization within the whole heart at 3 T. Magn Reson Med 62:1368–1378

    Article  Google Scholar 

  8. Del Grande F, Santini F, Herzka DA, Aro MR, Dean CW, Gold GE, Carrino JA (2014) Fat-suppression techniques for 3-T MR imaging of the musculoskeletal system. Radiographics 34(1):217–233

    Article  Google Scholar 

  9. Bernstein MA, King KF, Zhou XJ (2004) Handbook of MRI pulse sequences. Academic Press, Chicago

    Google Scholar 

  10. Hennig J, Weigel M, Scheffler K (2003) Multiecho sequences with variable refocusing flip angles: optimization of signal behavior using smooth transitions between pseudo steady states (TRAPS). Magn Reson Med 49:527–535

    Article  Google Scholar 

  11. Loening AM, Saranathan M, Ruangwattanapaisarn N, Litwiller DV, Shimakawa A, Vasanawala SS (2015) Increased speed and image quality in single-shot fast spin echo imaging via variable refocusing flip angles. J Magn Reson Imaging 42:1747–1758

    Article  Google Scholar 

  12. Borthakur A, Wheaton A, Charagundla SR, Shapiro EM, Regatte RR, Akella SVS, Kneeland JB, Reddy R (2003) Three-dimensional T1ρ-weighted MRI at 1.5 Tesla. J Magn Reson Imaging 17:730–736

    Article  Google Scholar 

  13. Constable RT, Anderson AW, Zhong J, Gore JC (1992) Factors influencing contrast in fast spin-echo MR imaging. Magn Reson Imaging 10(4):497–511

    Article  CAS  Google Scholar 

  14. Gras V, Abbas Z, Shah NJ (2013) Spoiled FLASH MRI with slice selective excitation: signal equation with a correction term. Concepts Magn Reson 42:89–100

    Article  Google Scholar 

  15. Raddi A, Klose U (1999) Optimized shinnar-le roux RF 180° pulses in fast spin-echo measurements. J Magn Reson Imaging 9:613–620

    Article  CAS  Google Scholar 

  16. Bloch Equations Simulator, http://mrsrl.stanford.edu/brian/blochsim/

  17. Hargreaves BA, Vasanawala SS, Pauly JM, Nishimura DG (2001) Characterization and reduction of the transient response in steady-state MR imaging. Magn Reson Med 46(1):149–158

    Article  CAS  Google Scholar 

  18. Matson GB (1994) An integrated program for amplitude-modulated RF pulse generation and re-mapping with shaped gradients. Magn Reson Imaging 12(8):1205–1225

    Article  CAS  Google Scholar 

  19. Hennig J, Nauerth A, Friedburg H (1986) RARE imaging: a fast imaging method for clinical MR. Magn Reson Med 3(6):823–833

    Article  CAS  Google Scholar 

  20. Kato H, Kuroda M, Yoshimura K, Yoshida A, Hanamoto K, Kawasaki S, Shibuya K, Kanazawa S (2005) Composition of MRI phantom equivalent to human tissues. Med Phys 32(10):3199–3208

    Article  Google Scholar 

  21. https://www.acraccreditation.org/-/media/ACRAccreditation/Documents/MRI/LargePhantomGuidance.pdf

  22. Brown RW, Cheng YCN, Haacke EM, Thompson MR, Venkatesan R (2014) A closer look at radiofrequency pulses. In: Magnetic resonance imaging physical principles and sequence design, 2nd edn. Wiley, New York

  23. Nitz WR, Balzer T, Grosu DS, Allkemper T (2010) Principles of Magnetic Resonance. In: Reimer P, Parizel PM, Meaney JFM, Stichnoth FA (eds) Clinical MR Imaging. Springer, Berlin, Heidelberg

    Google Scholar 

  24. McQueen F, Clarke A, McHaffie A et al (2010) Assessment of cartilage loss at the wrist in rheumatoid arthritis using a new MRI scoring system. Ann Rheum Dis 69:1971–1975

    Article  Google Scholar 

  25. Glinatsi D, Lillegraven S, Haavardsholm EA, Eshed I, Conaghan PG, Peterfy C, Gandjbakhch F, Bird P, Bøyesen P, Døhn UM, Genant HK, Østergaard M (2015) Validation of the OMERACT magnetic resonance imaging joint space narrowing score for the wrist in a multireader longitudinal trial. J Rheumatol 42(12):2480–2485

    Article  Google Scholar 

  26. Peterfy CG (2001) Magnetic resonance imaging in rheumatoid arthritis: current status and future directions. J Rheumatol 28(5):1134–1142

    CAS  PubMed  Google Scholar 

  27. Brui E, Lepekhina A, Chegina D, Bukkieva T, Efimtcev A, Andreychenko A (2020) Benefits of a wireless metamaterial-based radiofrequency coil for clinical wrist MRI. In: AIP Conference Proceedings, 5th International Conference on Metamaterials and Nanophotonics, METANANO 2020 2300(1):020012 

  28. Barth M, Breuer F, Koopmans PJ, Norris DG, Poser BA (2016) Simultaneous multislice (SMS) imaging techniques. Magn Reson Med 75(1):63–81

    Article  Google Scholar 

  29. Graves MJ, Mitchell DG (2013) Body MRI artifacts in clinical practice: a physicist’s and radiologist’s perspective. J Magn Reson Imaging 38(2):269–287

    Article  Google Scholar 

  30. Engström M, Mårtensson M, Avventi E, Skare S (2015) On the signal-to-noise ratio efficiency and slab-banding artifacts in three-dimensional multislab diffusion-weighted echo-planar imaging. Magn Reson Med 73:718–725

    Article  Google Scholar 

  31. Shchelokova A, Ivanov V, Mikhailovskaya A, Kretov E, Sushkov I, Serebryakova S, Nenasheva E, Melchakova I, Belov P, Slobozhanyuk A, Andreychenko A (2020) Ceramic resonators for targeted clinical magnetic resonance imaging of the breast. Nat Commun 11:3840

    Article  Google Scholar 

Download references

Acknowledgements

This work was supported by the Ministry of Education and Science of the Russian Federation (075-15-2021-592). EAB acknowledges the support received under the Ostrogradsky Programme of the French Embassy in Russia.

Author information

Authors and Affiliations

Authors

Contributions

Study conception and design: AEA. Acquisition of data: SR, EAB. Analysis and interpretation of data: EAB, SR. Drafting of manuscript: EAB. Critical revision: DB, AEA.

Corresponding author

Correspondence to Ekaterina A. Brui.

Ethics declarations

Conflict of interest

The authors declare that they have no competing interests.

Ethical approval

For this type of study, no ethical approval is required

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Brui, E.A., Rapacchi, S., Bendahan, D. et al. Comparative analysis of SINC-shaped and SLR pulses performance for contiguous multi-slice fast spin-echo imaging using metamaterial-based MRI. Magn Reson Mater Phy 34, 929–938 (2021). https://doi.org/10.1007/s10334-021-00937-w

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10334-021-00937-w

Keywords

Navigation