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Two-dimensional accelerated MP-RAGE imaging with flexible linear reordering

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Magnetic Resonance Materials in Physics, Biology and Medicine Aims and scope Submit manuscript

Abstract

Object

Implementation of an accelerated Magnetization Prepared RApid Gradient Echo (MP-RAGE) sequence for T1 weighted neuroimaging; exploiting modern MRI technologies to minimize scan time while preserving the image quality.

Materials and methods

A custom MP-RAGE sequence was implemented on a state-of-the-art 3T MR scanner equipped with a 32-channel receiver array head coil. The sequence utilized a shifted CAIPIRINHA k y –k z under-sampling pattern combined with elliptical scanning and a two-dimensional view ordering scheme to achieve high parallel imaging acceleration factors at maintained image contrast.

Results

It could be shown that MP-RAGE accelerated in two k-space directions outperforms single direction acceleration, which is the common practice with standard view ordering. Applying the CAIPIRINHA technique in conjunction with elliptical scanning further increased this benefit.

Conclusion

By combining MP-RAGE with CAIPIRINHA sampling and elliptical scanning, the scan time can be reduced from 4–5 min to 2–3 min with insignificant reduction in image quality.

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Notes

  1. http://www.scipy.org.

  2. http://fsl.fmrib.ox.ac.uk/fsl/fslwiki/fsl_anat.

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Acknowledgments

The authors acknowledge Siemens Healthcare for support in the framework of the research collaboration, coordinated by Dr. Florian Meise. Valuable comments from Dr. Thorsten Feiweier (Siemens Healthcare) are also acknowledged. We are grateful for the final review of the manuscript by Katja Neumann (DZNE Magdeburg), Prof. Oliver Speck (DZNE Magdeburg) and Prof. Monique Breteler (DZNE Bonn).

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Authors and Affiliations

  1. German Center for Neurodegenerative Diseases (DZNE), Ernst-Robert-Curtius-Straße 12, 53117, Bonn, Germany

    Daniel Brenner, Rüdiger Stirnberg, Eberhard D. Pracht & Tony Stöcker

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  1. Daniel Brenner
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  2. Rüdiger Stirnberg
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  3. Eberhard D. Pracht
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  4. Tony Stöcker
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Correspondence to Daniel Brenner.

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Brenner, D., Stirnberg, R., Pracht, E.D. et al. Two-dimensional accelerated MP-RAGE imaging with flexible linear reordering. Magn Reson Mater Phy 27, 455–462 (2014). https://doi.org/10.1007/s10334-014-0430-y

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  • DOI: https://doi.org/10.1007/s10334-014-0430-y

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