High-resolution magnetic resonance imaging (MRI) of trabecular bone combined with quantitative image analysis represents a powerful technique to gain insight into trabecular bone micro-architectural derangements in osteoporosis and osteoarthritis. The increased signal-to-noise ratio of ultra high-field MR (≥7 Tesla) permits images to be obtained with higher resolution and/or decreased scan time compared to scanning at 1.5/3T. In this small feasibility study, we show high measurement precision for subregional trabecular bone micro-architectural analysis performed on 7T knee MR images. The results provide further support for the use of trabecular bone measures as biomarkers in clinical studies of bone disorders.
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Chang, G., Wang, L., Liang, G. et al. Reproducibility of subregional trabecular bone micro-architectural measures derived from 7-Tesla magnetic resonance images. Magn Reson Mater Phy 24, 121–125 (2011). https://doi.org/10.1007/s10334-010-0243-6
- Ultra high field
- 7 Tesla
- Trabecular bone