Skip to main content
SpringerLink
Log in

Dual-contrast single breath-hold 3D abdominal MR imaging

  • Research Article
  • Published:
Magnetic Resonance Materials in Physics, Biology and Medicine Aims and scope Submit manuscript

Abstract

Object: Multiple contrasts are often helpful for a comprehensive diagnosis. In 3D abdominal MRI, breath-hold techniques are preferred for single contrast acquisitions to avoid respiratory artifacts. In this paper, highly accelerated parallel MRI is used to acquire large 3D abdominal volumes with two different contrasts within a single breath-hold.

Material and methods: In vivo studies have been performed on six healthy volunteers, combining T 1- and T 2-weighted, gradient- or spin-echo based scans, as well as water/fat resolved imaging in a single breath-hold. These 3D scans were acquired with an acceleration factor of six, using a prototype 32-element receive array.

Results: The presented approach was tested successfully on all volunteers. The whole liver area was covered by a FOV of 350 ×  250 ×  200 mm3 for all scans with reasonable spatial resolution. Arbitrary scan protocols generating different contrasts have been shown to be combinable in this single breath-hold approach. Good spatial correspondence with negligible spatial offset was achieved for all different scan combinations acquired in overall breath-hold times between 15 and 25 s.

Conclusion: Enabled by highly parallel imaging technology, this study demonstrates the technical feasibility and the promising image quality of single breath-hold dual contrast MRI.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Semelka RC, Martin DR, Balci C, Lance T (2001) Focal liver lesions: comparison of dual-phase CT and multisequence multiplanar MR imaging including dynamic gadolinium enhancement. J Magn Reson Imaging 13:397–401

    Article  PubMed  CAS  Google Scholar 

  2. Klessen C, Asbach P, Kroencke TJ, Fischer T, Warmuth C, Stemmer A, Hamm B, Taupitz M (2005) Magnetic resonance imaging of the upper abdomen using a free-breathing T2-weighted turbo spin echo sequence with navigator triggered prospective acquisition correction. J Magn Reson Imaging 21:576–582

    Article  PubMed  Google Scholar 

  3. Sodickson DK, Manning WJ (1997) Simultaneous acquisition of spatial harmonics (SMASH): fast imaging with radiofrequency coil arrays. Magn Reson Med 38:591–603

    Article  PubMed  CAS  Google Scholar 

  4. Pruessmann KP, Weiger M, Scheidegger MB, Boesiger P (1999) SENSE: sensitivity encoding for fast MRI. Magn Reson Med 42:952–962

    Article  PubMed  CAS  Google Scholar 

  5. Griswold MA, Jakob PM, Heidemann RM, Nittka M, Jellus V, Wang J, Kiefer B, Haase A (2002) Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn Reson Med 47:1202–1210

    Article  PubMed  Google Scholar 

  6. Liu YL, Riederer SJ, Rossman PJ, Grimm RC, Debbins JP, Ehman RL (1993) A monitoring, feedback, and triggering system for reproducible breath-hold MR imaging. Magn Reson Med 30:507–511

    Article  PubMed  CAS  Google Scholar 

  7. Zhu Y, Hardy CJ, Sodickson DK, Giaquinto RO, Dumoulin CL, Kenwood G, Niendorf T, Lejay H, McKenzie CA, Ohliger MA, Rofsky NM (2004) Highly parallel volumetric imaging with a 32-element RF coil array. Magn Reson Med 52:869–877

    Article  PubMed  Google Scholar 

  8. Wintersperger BJ, Reeder SB, Nikolaou K, Dietrich O, Huber A, Greiser A, Lanz T, Reiser MF, Schoenberg SO (2006) Cardiac CINE MR imaging with a 32-channel cardiac coil and parallel imaging: impact of acceleration factors on image quality and volumetric accuracy. J Magn Reson Imaging 23:222–227

    Article  PubMed  Google Scholar 

  9. Nehrke K, Börnert P, Mazurkewitz P, Winkelmann R, Graesslin I (2006) Free-breathing whole-heart coronary MR angiography on a clinical scanner in four minutes. J Magn Reson Imaging 23:752–756

    Article  PubMed  Google Scholar 

  10. Doi K (2005) Current status and future potential of computer-aided diagnosis in medical imaging. Br J Radiol 78:S3-S19

    Article  PubMed  Google Scholar 

  11. Danilouchkine MG, Westenberg JJ, van Assen HC, van Reiber JH, Lelieveldt BP (2005) 3D model-based approach to lung registration and prediction of respiratory cardiac motion. Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv 8:951–959

    PubMed  Google Scholar 

  12. Noble NM, Muthurangu V, Boubertakh R, Winkelmann R, Johnson RA, Hedge S, Börnert P, Razavi RS, Hill DL (2006) 32-Channel non-angulated cine cardiac volumes—automatic reformatting. In: Proceedings of 14th scientific annual meeting, Seattle, p. 791

  13. Weiger M, Pruessmann KP, Boesiger P (2002) 2D SENSE for faster 3D MRI. Magn Reson Mater Phy 14:10–19

    Google Scholar 

  14. Wiesinger F, Boesiger P, Pruessmann KP (2004) Electrodynamics and ultimate SNR in parallel MR imaging.Magn Reson Med 52:376–390

    Article  PubMed  Google Scholar 

  15. Feinberg DA, Hale JD, Watts JC, Kaufman L, Mark A (1986) Halving MR imaging time by conjugation: demonstration at 3.5 kG. Radiology 161:527–531

    PubMed  CAS  Google Scholar 

  16. Hargreaves BA, Gold GE, Lang PK, Conolly SM, Pauly JM, Bergman G, Vandevenne J, Nishimura DG (1999) MR imaging of articular cartilage using driven equilibrium. Magn Reson Med 42:695–703

    Article  PubMed  CAS  Google Scholar 

  17. Reeder SB, Wen Z, Yu H, Pineda AR, Gold GE, Markl M, Pelc NJ (2004) Multicoil Dixon chemical species separation with an iterative least-squares estimation method. Magn Reson Med 51:35–45

    Article  PubMed  CAS  Google Scholar 

  18. Shankaranarayanan A, Sodickson D, Giaquinto R, Grant A, Carrillo A, Gurr D, Madhuranthakam A, Yu H, Shimakawa A, Joshi S, Dumoulin C, Reeder S, Steger T, Brau A, Farrar N, Rofsky N, LaRuche S, Brittain J, McKenzie C (2006) Highly accelerated IDEAL for volumetric abdominal imaging with fat-water separation in a single breath-hold. In: Proceedings of the 14th scientific annual meeting, Seattle, p. 2453

  19. Feinberg DA, Turner R, Jakab PD, von Kienlin M (1990) Echo-planar imaging with asymmetric gradient modulation and inner-volume excitation. Magn Reson Med 13:162–169

    Article  PubMed  CAS  Google Scholar 

  20. Herborn CU, Vogt F, Lauenstein TC, Goyen M, Debatin JF, Ruehm SG (2003) MRI of the liver: can True FISP replace HASTE? J Magn Reson Imaging 17:190–196

    Article  PubMed  Google Scholar 

  21. Kovanlikaya A, Mittelman SD, Ward A, Geffner ME, Dorey F, Gilsanz V (2005) Obesity and fat quantification in lean tissues using three-point Dixon MR imaging. Pediatr Radiol 35:601–607

    Article  PubMed  Google Scholar 

  22. Pineda AR, Reeder SB, Wen Z, Pelc NJ (2005) Cramer-Rao bounds for three-point decomposition of water and fat. Magn Reson Med. 54:625–635

    Article  PubMed  Google Scholar 

  23. Taylor AM, Jhooti P, Keegan J, Simonds AK, Pennell DJ (1999) Magnetic resonance navigator echo diaphragm monitoring in patients with suspected diaphragm paralysis. J Magn Reson Imaging 9:69–74

    Article  PubMed  CAS  Google Scholar 

  24. Fischl B, Salat DH, van der Kouwe AJ, Makris N, Segonne F, Quinn BT, Dale AM (2004) Sequence-independent segmentation of magnetic resonance images. Neuroimage 2:69–84

    Article  Google Scholar 

  25. Sachs TS, Meyer CH, Hu BS, Kohli J, Nishimura DG, Macovski A (1994) Real-time motion detection in spiral MRI using navigators. Magn Reson Med 32:639–645

    Article  PubMed  CAS  Google Scholar 

  26. Schaeffter T, Rasche V, Carlsen IC (1999) Motion compensated projection reconstruction. Magn Reson Med 41:954–963

    Article  Google Scholar 

  27. Stehning C, Börnert P, Nehrke K, Eggers H, Stuber M (2005) Free-breathing whole-heart coronary MRA with 3D radial SSFP and self-navigated image reconstruction. Magn Reson Med 54:476–480

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Biomedical Engineering, University of Karlsruhe, 76128, Karlsruhe, Germany

    Richard Winkelmann & Olaf Dössel

  2. Philips Research Europe - Hamburg, Roentgenstr. 24–26, 22335, Hamburg, Germany

    Peter Börnert & Peter Mazurkewitz

  3. Philips Medical Systems, Best, The Netherlands

    Jan De Becker & Romhild Hoogeveen

Authors
  1. Richard Winkelmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Peter Börnert
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jan De Becker
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Romhild Hoogeveen
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Peter Mazurkewitz
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Olaf Dössel
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Richard Winkelmann.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Winkelmann, R., Börnert, P., De Becker, J. et al. Dual-contrast single breath-hold 3D abdominal MR imaging. Magn Reson Mater Phy 19, 297–304 (2006). https://doi.org/10.1007/s10334-006-0057-8

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10334-006-0057-8

Keywords

Search

Navigation