The Chinese-German Journal of Clinical Oncology

, Volume 12, Issue 12, pp 564–567 | Cite as

Effect and mechanism of 125I radioactive particles interposed radiotherapy between organizations on lung cancer

  • Jun LiangEmail author
  • Jianwu Xi
  • Huijuan Pan
  • Ying Qian
  • Dan Xu
  • Min Li



The aim of this study was to evaluate effect and mechanism of 125I radioactive particles interposed radiotherapy between organizations on lung cancer.


Fourteen cases of patients diagnosed with non-small cell lung cancer (NSCLC), the use of the B-, CT-guided, according to preoperative imaging and treatment planning system (TPS) program for radioactive particles interposed 125I interstitial radiotherapy.


All patients were successfully 125I interstitial radioactive particles interposed radiotherapy. Postoperative local complete tumor remission in 9 cases, partial remission in 5 cases, the efficiency of 100%. No case of serious complications. After 3 to 4 weeks of chemotherapy after 11 cases. 4 cases of lung cancer with bone metastases, pain completely disappeared after treatment. Up to now, five cases have died due to tumor progression, survival time of 12 to 16 months. Nine cases still under follow-up observation and treatment.


125I radioactive particles interposed radiotherapy between organizations of lung cancer, simple operation, trauma, fewer complications, conformal high, high local tumor dose, efficacy, and is a supplement of modern radiotherapy techniques for the treatment of lung cancer provides a comprehensive line of the method of effective.

Key words

125I radioactive particles lung cancer radiotherapy 


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  1. 1.
    Chen Y, Sun XH, Zhao JB, et al. Advanced non-small cell lung cancer retrospective study of prognostic factors. Chin J Clinicians (Electronic Edition, Chinese), 2011, 9: 142–146.Google Scholar
  2. 2.
    Liang J, Li SB, Yin Q. Insertion of radioactive particle 125I interstitial radiotherapy treatment of malignant tumors of the clinical setting analysis. Chin J Clinicians(Electronic Edition, Chinese), 2012, 4: 199–200.Google Scholar
  3. 3.
    Sun Y, Shi YK. Manual of medical oncology. BeiJing: People’s Medical Publishing, 2007. 258.Google Scholar
  4. 4.
    Yin WB, Yu ZH, Xu GZ, et al. Radiation oncology. BeiJing: China Union Medical University Press, 2008. 1–17.Google Scholar
  5. 5.
    Zhang GJ, Hao CJ, Ge MQ, et al. Microsurgery combined 5-FU and permanent 125I seed implantation treatment of recurrent glioma. Chin J Clinicians (Electronic Edition, Chinese), 2011, 9: 28–32.Google Scholar
  6. 6.
    Chai SD, Zheng GJ. Radioactive seed implantation for breast cancer. TianJin: Tianjin Science and Technology Press, 2007. 11.Google Scholar
  7. 7.
    Jun-jie Wang, Jing-fu Tang, Gong Li. Cancer brachytherapy radioactive particles. BeiJing: Beijing Medical University Press, 2001. 21–33.Google Scholar
  8. 8.
    Chai SD, Mao YQ, Yan LW, et al. Three-dimensional stereotactic brachytherapy radioactive seed planted tumor. Chin Clin Oncol (Chinese), 2005, 1: 77–79.Google Scholar
  9. 9.
    Shen WJ. Radioactive seed implantation status and progress. Chin J Mini Inv Surg (Chinese), 2007, 2: 118–119.Google Scholar
  10. 10.
    Yang DK, Qiu Y, Li D, et al. Intraoperative permanent implantation of radioactive I-125 seed for local advanced non small lung cancer. Chinese-German J Clin Oncol, 2007, 4: 191–192.CrossRefGoogle Scholar
  11. 11.
    Cesaretti JA, Stone NN, Stock RG. Urinary symptom flare following I-125 prostate bachytherapy. Int J Radiat Oncol Biol Pyhs, 2003, 56: 1085–1092.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Jun Liang
    • 1
    Email author
  • Jianwu Xi
    • 1
  • Huijuan Pan
    • 1
  • Ying Qian
    • 1
  • Dan Xu
    • 1
  • Min Li
    • 1
  1. 1.Department of OncologyThe People’s Hospital Wuxi Huishan RegionWuxiChina

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