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The Chinese-German Journal of Clinical Oncology

, Volume 11, Issue 9, pp 539–543 | Cite as

Treatment for triple-negative breast cancer

  • Xuebing Shi
  • Lu Wang
Article

Abstract

Triple-negative breast cancers (TNBCs) neither express estrogen receptor and progesterone receptor nor overexpress human epidermal growth factor receptor-2. Because of the special molecular features, triple-negative breast cancer is not either sensitive to endocrine therapy or targeted therapy of trastuzumab. There has not been standard treatment regimen for triple-negative breast cancer yet and chemotherapy has still been the chief therapy currently. However, with the great progress of oncology and molecular biology, the understanding of the natural history, pathophysiology and molecular features of this disease has been greatly improved, and a growing number of novel and effective therapies and discoveries of new biological targets for this phenotype of breast cancers have been reported, which provide new insights into therapeutic strategies for the women suffering from it.

Key words

triple-negative breast neoplasms therapy review 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Medical OncologyYijishan Hospital of Wannan Medical CollegeWuhuChina

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