Skip to main content
SpringerLink
Log in

Giant pedunculated sarcomatoid hepatocellular carcinoma: a case report

  • Published:
The Chinese-German Journal of Clinical Oncology

Abstract

We report a case who was a 74-year-old female with hepatitis B virus (HBV) carrier for more than 30 years. The serum levels of AFP, CEA and CA199 were within normal range. CT scan demonstrated that a huge pedunculated mass of the right hepatic lobe presenting as lobulated and cystic-solid appearance and heterogeneous density of the solid portion composed of multiple nodules. The patient was performed surgery, and the tumor was removed. Sarcomatoid hepatocellular carcinoma (SHC) was diagnosed by pathological and immunohistochemical test. The patient has been living for 4 months without tumor recurrence, which indicates that pedunculated SHC might have a high probability for resection and acquire better survival.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Maeda T, Adachi E, Kajiyama K, et al. Spindle cell hepatocellular carcinoma. A clinicopathologic and immunohistochemical analysis of 15 cases. Cancer, 1996, 77: 51–57.

    Article  PubMed  CAS  Google Scholar 

  2. Kakizoe S, Kojiro M, Nakashima T. Hepatocellular carcinoma with sarcomatous change. Clinicopathologic and immunohistochemical studies of 14 autopsy cases. Cancer, 1987, 59: 310–316.

    Article  PubMed  CAS  Google Scholar 

  3. Kojiro M, Sugihara S, Kakizoe S, et al. Hepatocellular carcinoma with sarcomatous change: a special reference to the relationship with anticancer therapy. Cancer Chemother Pharmacol, 1989, 23: S4–8.

    Article  PubMed  Google Scholar 

  4. Koo HR, Park MS, Kim MJ, et al. Radiological and clinical features of sarcomatoid hepatocellular carcinoma in 11 cases. J Comput Assist Tomogr, 2008, 32: 745–749.

    Article  PubMed  Google Scholar 

  5. Thompson L, Chang B, Barsky SH. Monoclonal origins of malignant mixed tumors (carcinosarcomas). Evidence for a divergent histogenesis. Am J Surg Pathol, 1996, 20: 277–285.

    Article  PubMed  CAS  Google Scholar 

  6. Murata M, Miyoshi Y, Iwao K, et al. Combined hepatocellular/cholangiocellular carcinoma with sarcomatoid features: genetic analysis for histogenesis. Hepatol Res, 2001, 21: 220–227.

    Article  PubMed  Google Scholar 

  7. Haratake J, Horie A. An immunohistochemical study of sarcomatoid liver carcinomas. Cancer, 1991, 68: 93–97.

    Article  PubMed  CAS  Google Scholar 

  8. Koda M, Maeda Y, Matsunaga Y, et al. Hepatocellular carcinoma with sarcomatous change arising after radiofrequency ablation for well-differentiated hepatocellular carcinoma. Hepatol Res, 2003, 27: 163–167.

    Article  PubMed  Google Scholar 

  9. Tsujimoto M, Aozasa K, Nakajima Y, et al. Hepatocellular carcinoma with sarcomatous proliferation showing an unusual and wide spread metastasis. Acta Pathol Jpn, 1984, 34: 839–845.

    PubMed  CAS  Google Scholar 

  10. Hwang S, Lee SG, Lee YJ, et al. Prognostic impact of sarcomatous change of hepatocellular carcinoma in patients undergoing liver resection and liver transplantation. J Gastrointest Surg, 2008, 12: 718–724.

    Article  PubMed  Google Scholar 

  11. Eriguchi N, Aoyagi S, Okuda K, et al. Unusual carcinomas with sarcomatous features: analysis of four cases. Surg Today, 2001, 31: 530–533.

    Article  PubMed  CAS  Google Scholar 

  12. Han JH, Park YN, Jung WH. A case with sarcomatoid hepatocellular carcinoma. Yonsei Med J, 1998, 39: 390–394.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Hepatobiliary Surgery, The General Hospital of Jinan Military Command, Jinan, 250031, China

    Jianping Zhang, Jialian Ni & Baozhen Zheng

Authors
  1. Jianping Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jialian Ni
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Baozhen Zheng
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jianping Zhang.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zhang, J., Ni, J. & Zheng, B. Giant pedunculated sarcomatoid hepatocellular carcinoma: a case report. Chin. -Ger. J. Clin. Oncol. 10, 669–671 (2011). https://doi.org/10.1007/s10330-011-0882-8

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10330-011-0882-8

Key words

Search

Navigation