Abstract
Objective
The aim of our study was to explore the correlations between C-reactive protein (CRP) levels and clinical stages of nasopharyngeal carcinoma (NPC).
Methods
We analyzed 108 cases, among them, 68 cases were NPC, 20 cases were benign inflammatory diseases of nasopharynx, 20 cases were healthy volunteers as control. CRP was determined with immunoturbidimetry (ITM).
Results
The mean concentrations of CRP in NPC (19.76 mg/L) were significantly increased compared to that in the control group (6.23 mg/L), while were significantly lower than that in benign inflammatory group (45.63 mg/L); The mean concentrations of CRP in T4 group (25.58 mg/L) were higher than that in T1 group (17.35 mg/L), T2 group (18.65 mg/L) and T3 group (15.61 mg/L). The mean concentrations of CRP in N3 group (28.04 mg/L) were higher than that in N0 (17.62 mg/L), N1 (21.27 mg/L), N2 (18.62 mg/L) respectively, the mean concentrations of CRP in IV (25.74 mg/L) were higher than that in I (14.20 mg/L), II (16.10 mg/L), III (23.01 mg/L), respectively.
Conclusion
The serum CRP level is associated with the occurrence of NPC and benign inflammatory disease of nasopharynx. In NPC, the CRP level has positive relationship with the TNM stage.
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Jiang, C., Li, J., Ao, F. et al. Relationship between C-reactive protein and clinical stage in nasopharyngeal carcinoma. Chin. -Ger. J. Clin. Oncol. 9, 89–92 (2010). https://doi.org/10.1007/s10330-009-0183-7
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DOI: https://doi.org/10.1007/s10330-009-0183-7