Abstract
Objective
The aim of this study was to investigate the value of multi-slice spiral CT (MSCT) in the diagnosis of malignant gastrointestinal stromal tumors (GISTs).
Methods
Twenty-seven cases of MSCT images of malignant GIST proved by surgery and pathology were retrospectively analyzed. Both plain and enhanced CT scan was performed and multiplanar reconstruction was made in all cases.
Results
The lesions originated from the stomach (n = 11), small intestine (n = 9), colon (n = 4), rectum (n = 1), and mesentery (n = 2). The transverse diameters of mass were 4.2–22 cm, the edges clearly (n = 12), unclearly (n = 15). The mass were mainly irregular in shape lobulated (n = 19). The lesions were mainly heterogeneity on plain scan, moderate to marked enhancement in arterial phase and durative enhanced in venous phase. Cystic necrosis were observed in all the lesions, 9 cases were cystic and solid mixed mass. Hepatic metastases (n = 4), pulmonary metastasis (n = 1), lymphatic metastasis (n = 2) were detected. The accuracy rate of MSCT diagnosis for location and pathologic features of GISTs were 85.2% (23/27) and 77.8% (21/27).
Conclusion
Two-phase MSCT examination and axial images combined with multiplanar reconstruction images have important value for diagnosis of malignant GIST.
Similar content being viewed by others
References
Tworek JA, Appelman HD, Singoeton TP, et al. Stromal tumors of the jejunum and ileum. Mod Pathology, 1997, 10: 200–209.
Lin F, Huang YQ, Du H, et al. Clinicopathologic characteristics and treatment of malignant gastrointestinal stromal tumor. Clin Med Chin (Chinese), 2005, 21: 519–521.
Hou YY, Zhu XZ. Clinicopathologic study advancement of gastrointestinal stromal tumor. J Pract Oncol (Chinese), 2003,18: 257–259.
Emory TS, Sobin LH, Lukes L, et al. Prognosis of gastrointestinal smooth-muscal (stromal) tumors: dependence on anatomic site. Am J Surg Patho,l 1999, 23: 82–87.
Tang GJ, Zhou XZ. Gastrointestinal stromal tumors: CT diagnosis. Chin J Radiol (Chinese), 2006, 40: 843–845.
Burkill GJ, Badran M, Al-Muderis O, et al. Malignant gastrointestinal stromal tumor: distribution, imaging features, and pattern of metastatic spread. Radiology, 2003, 226: 527–532.
Fang SH, Luo YX, Meng L, et al. CT Diagnosis of gastrointestinal stromal tumors. J Clinl Radiol (Chinese), 2002, 21: 280–282.
Liu GX, Liu XB, Yang H, et al. CT diagnosis of gastrointestinal stromal tumors. J Pract Radiol (Chinese), 2007, 23: 487–489.
Xu YS, Wu CF, Shen JL, et al. X-ray diagnosis of gastrointestinal stromal tumor (a report of 15 cases analysis). Radiol Pract (Chinese), 2003, 18: 598–600.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
He, Z., Lv, F., Cao, Z. et al. Value of multi-slice spiral CT in diagnosis of malignant gastrointestinal stromal tumors. Chin. -Ger. J. Clin. Oncol. 8, 443–446 (2009). https://doi.org/10.1007/s10330-009-0102-y
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10330-009-0102-y