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The extent and value of lymphadenectomy in the surgical treatment of gastroesophageal junction carcinoma

  • Published:
The Chinese-German Journal of Clinical Oncology

Abstract

Objective

We studied the extent and value of the lymphadenectomy in surgical treatment of carcinoma of gastroesophageal junction (GEJ).

Methods

217 patients with GEJ who underwent surgical resection were retrospectively analyzed. The extent of lymphadenectomy was divided into 5 types (D0 to D4) and the curability of operation was graded as A, B and C.

Results

The patients had been treated as follows: 186 with proximal gastrectomy, 31 with total gastrectomy, 97 with a combined-visceral resection. The patients who underwent D1, D2 and D3 lymphadenectomy were respectively 158, 58 and 1. The patients who were performed with resection of grade A, B and C were 53, 107 and 57 respectively. All patients were performed with a lymphadenectomy and well registered. The lymph node metastasis occurred in 157 cases (72.4%). The lymph node metastasis rate in the group 1, 2, 3, 4, 7, 9, 12 and 110 as well as in the pulmonary ligament group were higher than other groups. 2868 lymph nodes were removed, in which 655 (22.8%) demonstrated the existence of metastasis. The total lymph node metastatic degree in these groups was higher compared to the other groups.

Conclusion

The survival rate in the D1 lymphadenectomy and D2 is similar for all patients, and there may be some differences in the 2nd and 3rd years for the D1 lymphadenectomy and D2 in the stage-IIIb patients. The survival rate of D2 lymphadenectomy in stage IIIb is better than D1 and that of D2 lymphadenectomy is superior to D1 in stage-IV patients. The survival rate of grade A and B operation is much better than grade C, and the survival rate of grade A is also higher than B.

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Authors and Affiliations

  1. Department of Esophageal Cancer, Cancer Hospital of Tianjin Medical University, Tianjin, 300060, China

    Xijiang Zhao, Xiangming Liu, Peng Tang, Peng Ren & Mingquan Ma

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  1. Xijiang Zhao
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  2. Xiangming Liu
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  3. Peng Tang
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Correspondence to Xijiang Zhao.

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Zhao, X., Liu, X., Tang, P. et al. The extent and value of lymphadenectomy in the surgical treatment of gastroesophageal junction carcinoma. Chin. -Ger. J. Clin. Oncol. 8, 438–442 (2009). https://doi.org/10.1007/s10330-009-0086-7

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  • DOI: https://doi.org/10.1007/s10330-009-0086-7

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