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Primates

, Volume 55, Issue 3, pp 441–445 | Cite as

Seroprevalence of Japanese encephalitis virus infection in captive Japanese macaques (Macaca fuscata)

  • Hiroshi Shimoda
  • Akatsuki Saito
  • Keita Noguchi
  • Yutaka Terada
  • Ryusei Kuwata
  • Hirofumi Akari
  • Tomohiko Takasaki
  • Ken MaedaEmail author
Original Article

Abstract

Japanese encephalitis virus (JEV), which is transmitted by mosquitoes, infects many animal species and causes serious acute encephalitis in humans and horses. In this study, a serosurvey of JEV in Japanese macaques (Macaca fuscata) reared in Aichi Prefecture was conducted using purified JEV as an antigen for ELISA. The results revealed that 146 of 332 monkeys (44 %) were seropositive for JEV. In addition, 35 of 131 monkeys (27 %) born in the facility were seropositive, and the annual infection rate in the facility was estimated as 13 %. Our results provide evidence of the frequent exposure of many Japanese macaques to JEV, suggesting that there is a risk of JEV transmission to humans by mosquitoes.

Keywords

ELISA Japanese encephalitis virus Macaca fuscata Monkeys 

Notes

Acknowledgments

This work was supported by a Grant-in-Aid for a Japan Society for the Promotion of Science Fellowship and a grant from the Ministry of Health, Labour, and Welfare of Japan (H20-Shinko-Ippan-003).

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Copyright information

© Japan Monkey Centre and Springer Japan 2014

Authors and Affiliations

  • Hiroshi Shimoda
    • 1
  • Akatsuki Saito
    • 2
  • Keita Noguchi
    • 1
  • Yutaka Terada
    • 1
  • Ryusei Kuwata
    • 1
  • Hirofumi Akari
    • 2
  • Tomohiko Takasaki
    • 3
  • Ken Maeda
    • 1
    Email author
  1. 1.Laboratory of Veterinary Microbiology, Joint Faculty of Veterinary MedicineYamaguchi UniversityYamaguchiJapan
  2. 2.Center for Human Evolution Modeling Research, Primate Research InstituteKyoto UniversityInuyamaJapan
  3. 3.Division 2, Department of Virology 1National Institute of Infectious DiseasesShinjyukuJapan

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