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NRAMP1 polymorphism in a hybrid population between Japanese and Taiwanese macaques in Wakayama, Japan

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A macaque population produced by the hybridization of native Japanese macaques (Macaca fuscata) and introduced Taiwanese macaques (M. cyclopis) in Wakayama Prefecture was shown to possess three DNA haplotypes of the natural resistance-associated macrophage protein 1 (NRAMP1). Based on genotyping and comparison with M. fuscata populations, it was revealed that the introduced M. cyclopis population was polymorphic for the NRAMP1 locus. Extensive crossbreeding of the introduced species with the native species was confirmed using this genetic marker and the proportion of M. cyclopis genes was 57.4%. Results of statistical tests suggested non-random mating in the hybrid population.

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I wish to thank prefectural authority of Wakayama Prefecture for allowing me the opportunity to undertake this study. I am indebted to Mr. Kei Shirai and other members of Wildlife Management Office, Kawasaki, Japan, for sample collection and information. I am grateful to Mr. Shingo Maekawa, Drs. Hideo Nigi, Hideyuki Ohsawa, Shunji Gotoh, Yasuyuki Muroyama, Tamaki Maruhashi and Harumi Torii for their help and cooperation. I also thank Dr. Jan R. de Ruiter for helpful suggestions on the manuscript. This study was supported in part by Grants-in-Aid for General Scientific Research (13440256 and 16310156) and the MEXT Grant-in-Aid for the 21st Century COE Program (A2 to Kyoto University) from the Ministry of Education, Culture, Sports, Science and Technology, Japan.

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Correspondence to Yoshi Kawamoto.

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Kawamoto, Y. NRAMP1 polymorphism in a hybrid population between Japanese and Taiwanese macaques in Wakayama, Japan. Primates 46, 203–206 (2005).

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