Abstract
Microbial biosurfactants are sustainable alternatives for synthetic counterparts, and display high biodegradability, environmental compatibility, and high selectivity. While previous reports have focussed on production yield, little attention has been paid on downstream processing of biosurfactants, a critical step that controls quality. Here we review methods for biosurfactant downstream processing with focus on glycolipids and lipopeptidesglycolipids and lipopeptides. Solvent extraction, foam fractionation, and sweep floc coagulation allow to reach a purity of 55–70%. While distillation can be implemented prematurely, methods like ultrafiltration and chromatography are used as final processing to recover 90–95% of biosurfactant with 78–95% of purity. We present the cheapest and most efficient downstream techniques for industries to achieve acceptable product quality. This paper puts forth the environmental applications of biosurfactants. We review applications in treating hydrophobic organic pollutants and heavy metals in soils and water. The removal efficiency of biosurfactants reaches 96%. Biosurfactants in the detergent industry, microbial enhanced oil recovery, and soil washing are also discussed.
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Abbreviations
- LMW:
-
Low molecular weight
- HWM:
-
High molecular weight
- CMC:
-
Critical micellar concentration
- MEOR:
-
Microbial enhanced oil recovery
- ROG:
-
Residual oil grease
- TLC:
-
Thin layer chromatography
- HPLC:
-
High-performance liquid chromatography
- PAH:
-
Poly aromatic hydrocarbons
- EPA:
-
Environmental protection agency
- EDTA:
-
Ethylenediaminetetraacetic acid
- DEAE:
-
Diethylaminoethyl cellulose
- MEL:
-
Mannosylerythritol lipid
References
Abdel-Mawgoud AM, Lépine F, Déziel E (2010) Rhamnolipids: diversity of structures, microbial origins and roles. Appl Microbio Biotechnol 86(5):1323–1336. https://doi.org/10.1007/s00253-010-2498-2
Abyaneh AS, Fazaelipoor MH (2016) Evaluation of rhamnolipid (RL) as a biosurfactant for the removal of chromium from aqueous solutions by precipitate flotation. J Environ Manag 165:184–187. https://doi.org/10.1016/j.jenvman.2015.09.034
Aghajani M, Rahimpour A, Amani H, Taherzadeh MJ (2018) Rhamnolipid as new bio-agent for cleaning of ultrafiltration membrane fouled by whey. Eng Life Sci 18(5):272–280. https://doi.org/10.1002/elsc.201700070
Ahmad Z, Crowley D, Marina N, Jha SK (2016) Estimation of biosurfactant yield produced by Klebseilla sp. FKOD36 bacteria using artificial neural network approach. Measurement 81:163–173. https://doi.org/10.1016/j.measurement.2015.12.019
Ahmadi M, Niazi F, Jaafarzadeh N, Ghafari S, Jorfi S (2021) Characterization of the biosurfactant produced by Pesudomonas areuginosa strain R4 and its application for remediation pyrene-contaminated soils. J Environ Health Sci Eng 19(1):445–456. https://doi.org/10.1007/s40201-021-00617-w
Akanji LT, Rehman R, Onyemara CC, Ebel R, Jamal A (2021) A novel technique for interface analysis: Behaviour of sophorolipids biosurfactant obtained from Meyerozyma spp MF138126 during low-salinity heavy-crude experiments. Fuel 297:120607. https://doi.org/10.1016/j.fuel.2021.120607
Akbari A, Kasprzyk A, Galvez R, Ghoshal S (2021) A rhamnolipid biosurfactant increased bacterial population size but hindered hydrocarbon biodegradation in weathered contaminated soils. Sci Total Environ 778:145441. https://doi.org/10.1016/j.scitotenv.2021.145441
Al-agamy M, Hamed MM, Alhuzani MR, Youssif, AM (2021) Biosurfactant production by marine actinomycetes isolates streptomyces althioticus RG3 and Streptomyces Californicus RG8 as a promising source of antimicrobial and antifouling effects https://doi.org/10.21203/rs.3.rs-443724/v1
Al-Ajlani MM, Sheikh MA, Ahmad Z, Hasnain S (2007) Production of surfactin from Bacillus subtilis MZ-7 grown on pharmamedia commercial medium. Microb 6(1):1–8. https://doi.org/10.1186/1475-2859-6-17
Al-Bahry S, Al-Wahaibi Y, Elshafie A, Al-Bemani A, Joshi S, Al-Makhmari H, Al-Sulaimani H (2013) Biosurfactant production by Bacillus subtilis B20 using date molasses and its possible application in enhanced oil recovery. Int Biodeterior Biodegrad 81:141–146. https://doi.org/10.1016/j.ibiod.2012.01.006
Alimadadi N, Soudi M, Talebpour Z (2018) Efficient production of tri-acetylated mono-acylated mannosylerythritol lipids by Sporisorium sp aff sorghi SAM 20. J Appl Microbiol 124(2):457–468. https://doi.org/10.1111/jam.13642
Amani H, Sarrafzadeh MH, Haghighi M, Mehrnia MR (2010) Comparative study of biosurfactant producing bacteria in MEOR applications. J Pet Sci Eng 75(1–2):209–214. https://doi.org/10.1016/j.petrol.2010.11.008
Amani H, Müller MM, Syldatk C, Hausmann R (2013) Production of microbial rhamnolipid by Pseudomonas aeruginosa MM1011 for ex situ enhanced oil recovery. Appl Biochem Biotechnol 170(5):1080–1093. https://doi.org/10.1007/s12010-013-0249-4
Anyanwu C, Obi S, Okolo B (2011) Lipopeptide biosurfactant production by Serratia marcescens NSK-1 strain isolated from petroleum-contaminated soil Res J Appl Sci 79-87
Archana K, Sathi Reddy K, Parameshwar J, Bee H (2019) Isolation and characterization of sophorolipid producing yeast from fruit waste for application as antibacterial agent. Geogr Environ Sustain 2(2):107–115. https://doi.org/10.1007/s42398-019-00069-x
Ayed HB, Jemil N, Maalej H, Bayoudh A, Hmidet N, Nasri M (2015) Enhancement of solubilization and biodegradation of diesel oil by biosurfactant from Bacillus amyloliquefaciens An6. Int Biodeterior Biodegrad 99:8–14. https://doi.org/10.1016/j.ibiod.2014.12.009
Bages-Estopa S, White D, Winterburn J, Webb C, Martin P (2018) Production and separation of a trehalolipid biosurfactant. Biochem Eng J 139:85–94. https://doi.org/10.1016/j.bej.2018.07.006
Bagheri LT, Shahcheraghi F, Shooraj F (2013) Assessment of antibacterial capability of rhamnolipids produced by two indigenous Pseudomonas aeruginosa strains. Jundishapur J Microbiol 2013:29–35. https://doi.org/10.5812/jjm.2662
Bajaj V, Tilay A, Annapure U (2012) Enhanced production of bioactive sophorolipids by Starmerella bombicola NRRL Y-17069 by design of experiment approach with successive purification and characterization. J Oleo Sci 61(7):377–386. https://doi.org/10.5650/jos.61.377
Bak F, Bonnichsen L, Jørgensen NO, Nicolaisen MH, Nybroe O (2015) The biosurfactant viscosin transiently stimulates n-hexadecane mineralization by a bacterial consortium. Appl Microbiol Biotechnol 99(3):1475–1483. https://doi.org/10.1007/s00253-014-6054-3
Baker SC, Chen CY (2010) Enrichment and purification of lipopeptide biosurfactants. Biosurfactants. https://doi.org/10.1007/978-1-4419-5979-9_21
Barakat KM, Hassan SW, Darwesh OM (2017) Biosurfactant production by haloalkaliphilic Bacillus strains isolated from Red Sea. Egypt Egypt J Aquat Res 43(3):205–211. https://doi.org/10.1016/j.ejar.2017.09.001
Basak G, Das N (2014) Characterization of sophorolipid biosurfactant produced by Cryptococcus sp VITGBN2 and its application on Zn (II) removal from electroplating wastewater. J Environ Biol 35(6):1087
Bednarski W, Adamczak M, Tomasik J, Płaszczyk M (2004) Application of oil refinery waste in the biosynthesis of glycolipids by yeast. Bioresour Technol 95(1):15–18. https://doi.org/10.1016/j.biortech.2004.01.009
Beuker J, Steier A, Wittgens A, Rosenau F, Henkel M, Hausmann R (2016) Integrated foam fractionation for heterologous rhamnolipid production with recombinant Pseudomonas putida in a bioreactor. AMB Express 6(1):1–10. https://doi.org/10.1186/s13568-016-0183-2
Bezerra KGO, Rufino RD, Luna JM, Sarubbo LA (2018) Saponins and microbial biosurfactants: potential raw materials for the formulation of cosmetics. Biotechnol Prog 34(6):1482–1493. https://doi.org/10.1002/btpr.2682
Bezza FA, Chirwa EMN (2015a) Biosurfactant from Paenibacillus dendritiformis and its application in assisting polycyclic aromatic hydrocarbon (PAH) and motor oil sludge removal from contaminated soil and sand media. Process Saf Environ Prot 98:354–364. https://doi.org/10.1016/j.psep.2015.09.004
Bezza FA, Chirwa EMN (2015b) Production and applications of lipopeptide biosurfactant for bioremediation and oil recovery by Bacillus subtilis CN2. Biochem Eng J 101:168–178. https://doi.org/10.1016/j.bej.2015.05.007
Bezza FA, Beukes M, Chirwa EMN (2015) Application of biosurfactant produced by Ochrobactrum intermedium CN3 for enhancing petroleum sludge bioremediation. Process Biochem 50(11):1911–1922. https://doi.org/10.1016/j.procbio.2015.07.002
Biniarz P, Łukaszewicz M, Janek T (2017) Screening concepts, characterization and structural analysis of microbial-derived bioactive lipopeptides: a review. Crit Rev Biotechnol 37(3):393–410. https://doi.org/10.3109/07388551.2016.1163324
Biselli A, Willenbrink AL, Leipnitz M, Jupke A (2020) Development, evaluation, and optimisation of downstream process concepts for rhamnolipids and 3-(3-hydroxyalkanoyloxy) alkanoic acids. Sep Purif Technol 250:117031. https://doi.org/10.1016/j.seppur.2020.117031
Borah D, Chaubey A, Sonowal A, Gogoi B, Kumar R (2021) Microbial biosurfactants and their potential applications: an overview. Microbial Biosurfactants. https://doi.org/10.1007/978-981-15-6607-3_5
Bouassida M, Fourati N, Ghazala I, Ellouze-Chaabouni S, Ghribi D (2018) Potential application of Bacillus subtilis SPB1 biosurfactants in laundry detergent formulations: compatibility study with detergent ingredients and washing performance. Eng Life Sci 18(1):70–77. https://doi.org/10.1002/elsc.201700152
Bucci AR, Marcelino L, Mendes RK, Etchegaray A (2018) The antimicrobial and antiadhesion activities of micellar solutions of surfactin, CTAB and CPCl with terpinen-4-ol: applications to control oral pathogens. World J Microbiol Biotechnol 34(6):1–9. https://doi.org/10.1007/s11274-018-2472-1
Bustamante M, Duran N, Diez M (2012) Biosurfactants are useful tools for the bioremediation of contaminated soil: a review. Soil Sci Plant Nutr 12(4):667–687. https://doi.org/10.4067/S0718-95162012005000024
Castelein M, Verbruggen F, Van Renterghem L, Spooren J, Yurramendi L, Du Laing G, Boon N, Soetaert W, Hennebel T, Roelants S (2021) Bioleaching of metals from secondary materials using glycolipid biosurfactants. Miner Eng 163:106665. https://doi.org/10.1016/j.mineng.2020.106665
Chen HL, Juang RS (2008) Recovery and separation of surfactin from pretreated fermentation broths by physical and chemical extraction. Biochem Eng J 38(1):39–46. https://doi.org/10.1016/j.bej.2007.06.003
Chen Q, Bao M, Fan X, Liang S, Sun P (2013) Rhamnolipids enhance marine oil spill bioremediation in laboratory system. Mar Pollut Bull 71(1–2):269–275. https://doi.org/10.1016/j.marpolbul.2013.01.037
Chen WC, Juang RS, Wei YH (2015) Applications of a lipopeptide biosurfactant, surfactin, produced by microorganisms. Biochem Eng J 103:158–169. https://doi.org/10.1016/j.bej.2015.07.009
Chen C, Sun N, Li D, Long S, Tang X, Xiao G, Wang L (2018) Optimization and characterization of biosurfactant production from kitchen waste oil using Pseudomonas aeruginosa. Environ Sci Pollut Res 25(15):14934–14943. https://doi.org/10.1007/s11356-018-1691-1
Chen C, Li D, Li R, Shen F, Xiao G, Zhou J (2021) Enhanced biosurfactant production in a continuous fermentation coupled with in situ foam separation. Chem Eng Process 159:108206. https://doi.org/10.1016/j.cep.2020.108206
Chtioui O, Dimitrov K, Gancel F, Nikov I (2010) Biosurfactants production by immobilized cells of Bacillus subtilis ATCC 21332 and their recovery by pertraction. Process Biochem 45(11):1795–1799. https://doi.org/10.1016/j.procbio.2010.05.012
Cochrane SA, Vederas JC (2016) Lipopeptides from Bacillus and Paenibacillus spp: a gold mine of antibiotic candidates. Med Res Rev 36(1):4–31. https://doi.org/10.1002/med.21321
Coronel-León J, de Grau G, Grau-Campistany A, Farfan M, Rabanal F, Manresa A, Marqués AM (2015) Biosurfactant production by AL 1.1, a Bacillus licheniformis strain isolated from Antarctica: production, chemical characterization and properties. Ann Microbiol 65(4):2065–2078. https://doi.org/10.1007/s13213-015-1045-x
Coronel-León J, Marqués A, Bastida J, Manresa A (2016) Optimizing the production of the biosurfactant lichenysin and its application in biofilm control. J Appl Microbiol 120(1):99–111. https://doi.org/10.1111/jam.12992
Costa JA, Treichel H, Santos LO, Martins VG 2018 Solid-state fermentation for the production of biosurfactants and their applications Biotechnol Bioeng pp 357–372 https://doi.org/10.1016/B978-0-444-63990-5.00016-5
Coutte F, Lecouturier D, Leclère V, Béchet M, Jacques P, Dhulster P (2013) New integrated bioprocess for the continuous production, extraction and purification of lipopeptides produced by Bacillus subtilis in membrane bioreactor. Process Biochem 48(1):25–32. https://doi.org/10.1016/j.procbio.2012.10.005
Coutte F, Lecouturier D, Dimitrov K, Guez JS, Delvigne F, Dhulster P, Jacques P (2017) Microbial lipopeptide production and purification bioprocesses, current progress and future challenges. Biotechnol J 12(7):1600566. https://doi.org/10.1002/biot.201600566
Czinkóczky R, Németh Á (2020) Techno-economic assessment of Bacillus fermentation to produce surfactin and lichenysin. Biochem Eng J 163:107719. https://doi.org/10.1016/j.bej.2020.107719
Dalili D, Amini M, Faramarzi MA, Fazeli MR, Khoshayand MR, Samadi N (2015) Isolation and structural characterization of Coryxin, a novel cyclic lipopeptide from Corynebacterium xerosis NS5 having emulsifying and anti-biofilm activity. Colloids Surf B Biointerfaces 135:425–432. https://doi.org/10.1016/j.colsurfb.2015.07.005
Dardouri M, Mendes RM, Frenzel J, Costa J, Ribeiro IA (2021) Seeking faster, alternative methods for glycolipid biosurfactant characterization and purification. Anal Bioanal Chem. https://doi.org/10.1007/s00216-021-03387-4
Datta P, Tiwari P, Pandey LM (2018) Isolation and characterization of biosurfactant producing and oil degrading Bacillus subtilis MG495086 from formation water of Assam oil reservoir and its suitability for enhanced oil recovery. Bioresour Technol 270:439–448. https://doi.org/10.1016/j.biortech.2018.09.047
Datta P, Tiwari P, Pandey LM (2020) Oil washing proficiency of biosurfactant produced by isolated Bacillus tequilensis MK 729017 from Assam reservoir soil. J Pet Sci Eng 195:107612. https://doi.org/10.1016/j.petrol.2020.107612
Daverey A, Pakshirajan K (2010) Sophorolipids from Candida bombicola using mixed hydrophilic substrates: production, purification and characterization. Colloids Surf B Biointerfaces 79(1):246–253. https://doi.org/10.1016/j.colsurfb.2010.04.002
De Andrade CJ, De Andrade LM, Rocco SA, Sforça ML, Pastore GM, Jauregi P (2017) A novel approach for the production and purification of mannosylerythritol lipids (MEL) by Pseudozyma tsukubaensis using cassava wastewater as substrate. Sep Purif Technol 180:157–167. https://doi.org/10.1016/j.seppur.2017.02.045
De Rienzo MD, Kamalanathan I, Martin P (2016) Comparative study of the production of rhamnolipid biosurfactants by B thailandensis E264 and P aeruginosa ATCC 9027 using foam fractionation. Process Biochem 51(7):820–827. https://doi.org/10.1016/j.procbio.2016.04.007
De S, Malik S, Ghosh A, Saha R, Saha B (2015) A review on natural surfactants. RSC Adv 5(81):65757–65767. https://doi.org/10.1039/C5RA11101C
de Araujo LV, Guimarães CR, da Silva Marquita RL, Santiago VM, de Souza MP, Nitschke M, Freire DMG (2016) Rhamnolipid and surfactin: anti-adhesion/antibiofilm and antimicrobial effects. Food Control 63:171–178. https://doi.org/10.1016/j.foodcont.2015.11.036
Demling P, von Campenhausen M, Grütering C, Tiso T, Jupke A, Blank LM (2020) Selection of a recyclable in situ liquid–liquid extraction solvent for foam-free synthesis of rhamnolipids in a two-phase fermentation. Green Chem 22(23):8495–8510. https://doi.org/10.1039/D0GC02885A
Dhanarajan G, Sen R (2014) Cost analysis of biosurfactant production from a scientist’s perspective. Biosurfactants 159:153
Dhanarajan G, Rangarajan V, Sen R (2015) Dual gradient macroporous resin column chromatography for concurrent separation and purification of three families of marine bacterial lipopeptides from cell free broth. Sep Purif Technol 143:72–79. https://doi.org/10.1016/j.seppur.2015.01.025
Dimitrov K, Gancel F, Montastruc L, Nikov I (2008) Liquid membrane extraction of bio-active amphiphilic substances: recovery of surfactin. Biochem Eng J 42(3):248–253. https://doi.org/10.1016/j.bej.2008.07.005
Dlamini B, Rangarajan V, Clarke KG (2020) A simple thin layer chromatography based method for the quantitative analysis of biosurfactant surfactin vis-a-vis the presence of lipid and protein impurities in the processing liquid. Biocatal Agric Biotechnol 25:101587. https://doi.org/10.1016/j.bcab.2020.101587
Dolman BM, Wang F, Winterburn JB (2019) Integrated production and separation of biosurfactants. Process Biochem 83:1–8. https://doi.org/10.1016/j.procbio.2019.05.002
El Zeftawy MM, Mulligan CN (2011) Use of rhamnolipid to remove heavy metals from wastewater by micellar-enhanced ultrafiltration (MEUF). Sep Purif Technol 77(1):120–127. https://doi.org/10.1016/j.seppur.2010.11.030
Elakkiya VT, Sureshkumar P, Yoha K, Subhasri D (2021) Studies on antibacterial and chemotaxis properties of Pseudomonas aeruginosa TEN01 biomass-derived sustainable biosurfactant. Chemosphere 285:131381. https://doi.org/10.1016/j.chemosphere.2021.131381
Elazzazy AM, Abdelmoneim T, Almaghrabi O (2015) Isolation and characterization of biosurfactant production under extreme environmental conditions by alkali-halo-thermophilic bacteria from Saudi Arabia. Saudi J Biol Sci 22(4):466–475. https://doi.org/10.1016/j.sjbs.2014.11.018
Felix AKN, Martins JJ, Almeida JGL, Giro MEA, Cavalcante KF, Melo VMM, Pessoa ODL, Rocha MVP, Gonçalves LRB, de Santiago Aguiar RS (2019) Purification and characterization of a biosurfactant produced by Bacillus subtilis in cashew apple juice and its application in the remediation of oil-contaminated soil. Colloids Surf B Biointerfaces 175:256–263. https://doi.org/10.1016/j.colsurfb.2018.11.062
Fenibo EO, Douglas SI, Stanley HO (2019) A review on microbial surfactants: production, classifications, properties and characterization. Adv Appl Microbio. https://doi.org/10.9734/jamb/2019/v18i330170
Franco Marcelino PR, da Silva VL, Rodrigues Philippini R, Von Zuben CJ, Contiero J, Dos Santos JC, da Silva SS (2017) Biosurfactants produced by Scheffersomyces stipitis cultured in sugarcane bagasse hydrolysate as new green larvicides for the control of Aedes aegypti, a vector of neglected tropical diseases. PLoS ONE 12(11):e0187125. https://doi.org/10.1371/journal.pone.0187125
Franzetti A, Gandolfi I, Bestetti G, Smyth TJ, Banat IM (2010) Production and applications of trehalose lipid biosurfactants. Eur J Lipid Sci Technol 112(6):617–627. https://doi.org/10.1002/ejlt.200900162
Ganesan NG, Rangarajan V (2021) A kinetics study on surfactin production from Bacillus subtilis MTCC 2415 for application in green cosmetics. Biocatal Agric Biotechnol 33:102001. https://doi.org/10.1016/j.bcab.2021.102001
Geetha S, Banat IM, Joshi SJ (2018) Biosurfactants: Production and potential applications in microbial enhanced oil recovery (MEOR). Biocatal Agric Biotechnol 14:23–32. https://doi.org/10.1016/j.bcab.2018.01.010
Ghobadi R, Altaee A, Zhou JL, Karbassiyazdi E, Ganbat N (2021) Effective remediation of heavy metals in contaminated soil by electrokinetic technology incorporating reactive filter media. Sci Total Environ 794:148668. https://doi.org/10.1016/j.scitotenv.2021.148668
Giri SS, Ryu E, Sukumaran V, Park SC (2019) Antioxidant, antibacterial, and anti-adhesive activities of biosurfactants isolated from Bacillus strains. Microb Pathog 132:66–72. https://doi.org/10.1016/j.micpath.2019.04.035
Glazyrina J, Junne S, Thiesen P, Lunkenheimer K, Goetz P (2008) In situ removal and purification of biosurfactants by automated surface enrichment. Appl Microbiol Biotechnol 81(1):23–31. https://doi.org/10.1007/s00253-008-1620-1
Gudiña EJ, Rodrigues AI, de Freitas V, Azevedo Z, Teixeira JA, Rodrigues LR (2016a) Valorization of agro-industrial wastes towards the production of rhamnolipids. Bioresour Technol 212:144–150. https://doi.org/10.1016/j.biortech.2016.04.027
Gudiña EJ, Teixeira JA, Rodrigues LR (2016b) Biosurfactants produced by marine microorganisms with therapeutic applications. Mar Drugs 14(2):38. https://doi.org/10.3390/md14020038
Guez JS, Chenikher S, Cassar JP, Jacques P (2007) Setting up and modelling of overflowing fed-batch cultures of Bacillus subtilis for the production and continuous removal of lipopeptides. J Biotechnol 131(1):67–75. https://doi.org/10.1016/j.jbiotec.2007.05.025
Gupta S, Raghuwanshi N, Varshney R, Banat IM, Srivastava AK, Pruthi PA, Pruthi V (2017) Accelerated in vivo wound healing evaluation of microbial glycolipid containing ointment as a transdermal substitute. Biomed Pharmacother 94:1186–1196. https://doi.org/10.1016/j.biopha.2017.08.010
Gupta K (2021) Biosurfactant-based bioremediation of soil and aquatic contaminants in: Green chem 367–376 https://doi.org/10.1016/B978-0-12-822696-4.00002-4
Habe H, Taira T, Imura T (2018) Surface activity and Ca2+-dependent aggregation property of lichenysin produced by Bacillus licheniformis NBRC 104464. J Oleo Sci 67(10):1307–1313. https://doi.org/10.5650/jos.ess18107
Hajfarajollah H, Eslami P, Mokhtarani B, Akbari Noghabi K (2018) Biosurfactants from probiotic bacteria: a review. Biotechnol Appl Biochem 65(6):768–783. https://doi.org/10.1002/bab.1686
Hassan FWM, Raoov M, Kamaruzaman S, Mohamed AH, Ibrahim WNW, Hanapi NSM, Zain NNM, Yahaya N, Chen DDY (2021) A rapid and efficient dispersive trehalose biosurfactant enhanced magnetic solid phase extraction for the sensitive determination of organophosphorus pesticides in cabbage (Brassica olearaceae var capitate) samples by GC-FID. J Food Compos Anal. https://doi.org/10.1016/j.jfca.2021.104057
Hentati D, Chebbi A, Hadrich F, Frikha I, Rabanal F, Sayadi S, Manresa A, Chamkha M (2019) Production, characterization and biotechnological potential of lipopeptide biosurfactants from a novel marine Bacillus stratosphericus strain FLU5. Ecotoxicol Environ Saf 167:441–449. https://doi.org/10.1016/j.ecoenv.2018.10.036
Hmidet N, Ben Ayed H, Jacques P, Nasri M (2017) Enhancement of surfactin and fengycin production by Bacillus mojavensis A21: application for diesel biodegradation. BioMed Res Int. https://doi.org/10.1155/2017/5893123
Hogan DE, Tian F, Malm SW, Olivares C, Pacheco RP, Simonich MT, Hunjan AS, Tanguay RL, Klimecki WT, Polt R (2019) Biodegradability and toxicity of monorhamnolipid biosurfactant diastereomers. J Hazard Mater 364:600–607. https://doi.org/10.1016/j.jhazmat.2018.10.050
Hrůzová K, Patel A, Masák J, Maťátková O, Rova U, Christakopoulos P, Matsakas L (2020) A novel approach for the production of green biosurfactant from Pseudomonas aeruginosa using renewable forest biomass. Sci Total Environ 711:135099. https://doi.org/10.1016/j.scitotenv.2019.135099
Huang D, Wu ZL, Liu W, Hu N, Li HZ (2016) A novel process intensification approach of recovering creatine from its wastewater by batch foam fractionation. Chem Eng Process 104:13–21. https://doi.org/10.1016/j.cep.2016.02.005
Hubert J, Ple K, Hamzaoui M, Nuissier G, Hadef I, Reynaud R, Guilleret A, Renault JH (2012) New perspectives for microbial glycolipid fractionation and purification processes. C R Chim 15(1):18–28. https://doi.org/10.1016/j.crci.2011.11.002
Invally K, Sancheti A, Ju LK (2019) A new approach for downstream purification of rhamnolipid biosurfactants. Food Bioprod Process 114:122–131. https://doi.org/10.1016/j.fbp.2018.12.003
Irorere VU, Tripathi L, Marchant R, McClean S, Banat IM (2017) Microbial rhamnolipid production: a critical re-evaluation of published data and suggested future publication criteria. Appl Microbiol Biotechnol 101(10):3941. https://doi.org/10.1007/s00253-017-8262-0
Jadhav M, Kalme S, Tamboli D, Govindwar S (2011) Rhamnolipid from Pseudomonas desmolyticum NCIM-2112 and its role in the degradation of Brown 3REL. J Basic Microbiol 51(4):385–396. https://doi.org/10.1016/j.procbio.2019.01.01
Jadhav JV, Pratap AP, Kale SB (2019) Evaluation of sunflower oil refinery waste as feedstock for production of sophorolipid. Process Biochem 78:15–24. https://doi.org/10.1002/jobm.201000364
Jahan R, Bodratti AM, Tsianou M, Alexandridis P (2020) Biosurfactants, natural alternatives to synthetic surfactants: physicochemical properties and applications. Adv Colloid Interface Sci 275:102061. https://doi.org/10.1016/j.cis.2019.102061
Jauregi P, Coutte F, Catiau L, Lecouturier D, Jacques P (2013) Micelle size characterization of lipopeptides produced by B. subtilis and their recovery by the two-step ultrafiltration process. Sep Purif Technol 104:175–182. https://doi.org/10.1016/j.seppur.2012.11.017
Jauregi P, Kourmentza K (2019) Membrane filtration of biosurfactants in: Separation of functional molecules in food by membrane technology pp 79–112 https://doi.org/10.1016/B978-0-12-815056-6.00003-6
Jimoh AA, Lin J (2019) Biosurfactant: a new frontier for greener technology and environmental sustainability. Ecotoxicol Environ Saf 184:109607. https://doi.org/10.1007/s12010-020-03246-5
Jimoh AA, Lin J (2020) Bioremediation of contaminated diesel and motor oil through the optimization of biosurfactant produced by Paenibacillus sp D9 on waste canola oil. Bioremediat J 24(1):21–40. https://doi.org/10.1080/10889868.2020.1721425
Jimoh AA, Lin J (2020) Biotechnological applications of Paenibacillus sp D9 lipopeptide biosurfactant produced in low-cost substrates. Appl Biochem Biotechnol. https://doi.org/10.1016/j.ecoenv.2019.109607
Joy S, Khare SK, Sharma S (2020) Synergistic extraction using sweep-floc coagulation and acidification of rhamnolipid produced from industrial lignocellulosic hydrolysate in a bioreactor using sequential (fill-and-draw) approach. Process Biochem 90:233–240. https://doi.org/10.1016/j.procbio.2019.11.014
Juang RS, Chen HL, Tsao SC (2012) Recovery and separation of surfactin from pretreated Bacillus subtilis broth by reverse micellar extraction. Biochem Eng J 61:78–83. https://doi.org/10.1016/j.bej.2011.12.008
Jung J, Yu KO, Ramzi AB, Choe SH, Kim SW, Han SO (2012) Improvement of surfactin production in Bacillus subtilis using synthetic wastewater by overexpression of specific extracellular signaling peptides, comX and phrC. Biotechnol Bioeng 109(9):2349–2356. https://doi.org/10.1002/bit.24524
Karnwal A (2021) Biosurfactant production using bioreactors from industrial byproducts. Biosurfactants Sustain Future Prod Appl Environ Biomed. https://doi.org/10.1002/9781119671022.ch3
Khademolhosseini R, Jafari A, Mousavi SM, Hajfarajollah H, Noghabi KA, Manteghian M (2019) Physicochemical characterization and optimization of glycolipid biosurfactant production by a native strain of Pseudomonas aeruginosa HAK01 and its performance evaluation for the MEOR process. RSC Adv 9(14):7932–7947. https://doi.org/10.1039/C8RA10087J
Khondee N, Tathong S, Pinyakong O, Müller R, Soonglerdsongpha S, Ruangchainikom C, Tongcumpou C, Luepromchai E (2015) Lipopeptide biosurfactant production by chitosan-immobilized Bacillus sp. GY19 and their recovery by foam fractionation. Biochem Eng J 93:47–54. https://doi.org/10.1016/j.bej.2014.09.001
Kiran GS, Sabu A, Selvin J (2010) Synthesis of silver nanoparticles by glycolipid biosurfactant produced from marine Brevibacterium casei MSA19. J Biotechnol 148(4):221–225. https://doi.org/10.1016/j.jbiotec.2010.06.012
Kissoyan KA, Drechsler M, Stange EL, Zimmermann J, Kaleta C, Bode HB, Dierking K (2019) Natural C elegans microbiota protects against infection via production of a cyclic lipopeptide of the viscosin group. Curr Biol. 29(6):1030-1037 e5. https://doi.org/10.1016/j.cub.2019.01.050
Koirala N, Khanal S, Chaudhary S, Gautam S, Sah SN, Subba P, Marraiki N, Batiha GE-S (2020) Surfactant production by Bacillus subtilis using very low grade and cheap substrate https://doi.org/10.20944/preprints202008.0486.v1
Kosaric N, Sukan FV (2014) Biosurfactants: production and utilization—processes, technologies, and economics. CRC Press, USA
Kubicki S, Bollinger A, Katzke N, Jaeger KE, Loeschcke A, Thies S (2019) Marine biosurfactants: biosynthesis, structural diversity and biotechnological applications. Mar Drugs 17(7):408. https://doi.org/10.3390/md17070408
Kügler JH, Muhle-Goll C, Kühl B, Kraft A, Heinzler R, Kirschhöfer F, Henkel M, Wray V, Luy B, Brenner-Weiss G (2014) Trehalose lipid biosurfactants produced by the actinomycetes Tsukamurella spumae and T pseudospumae. Appl Microbiol Biotechnol 98(21):8905–8915. https://doi.org/10.1007/s00253-014-5972-4
Kumar R, Das AJ (2018) Extraction, detection, and characterization of rhamnolipid biosurfactants from microorganisms in: Rhamnolipid Biosurfactant pp 15–28 https://doi.org/10.1007/978-981-13-1289-2_2
Kumar PS, Ngueagni PT (2021) A review on new aspects of lipopeptide biosurfactant: types, production, properties and its application in the bioremediation process. J Hazard Mater 407:124827. https://doi.org/10.1016/j.jhazmat.2020.124827
Kuyukina MS, Ivshina IB (2019) Production of trehalolipid biosurfactants by Rhodococcus. Biology of Rhodococcus 271–298
Lan G, Fan Q, Liu Y, Chen C, Li G, Liu Y, Yin X (2015) Rhamnolipid production from waste cooking oil using Pseudomonas SWP-4. Biochem Eng J 101:44–54. https://doi.org/10.1016/j.bej.2015.05.001
Lee MH, Lee J, Nam YD, Lee JS, Seo MJ, Yi SH (2016) Characterization of antimicrobial lipopeptides produced by Bacillus sp. LM7 isolated from chungkookjang, a Korean traditional fermented soybean food. Int J Food Microbiol 221:12–18. https://doi.org/10.1016/j.ijfoodmicro.2015.12.010
Leyton A, Araya M, Tala F, Flores L, Lienqueo ME, Shene C (2021) Macrocystis pyrifera extract residual as nutrient source for the production of sophorolipids compounds by marine yeast Rhodotorula rubra. Molecules 26(8):2355. https://doi.org/10.3390/molecules26082355
Li J, Deng M, Wang Y, Chen W (2016) Production and characteristics of biosurfactant produced by Bacillus pseudomycoides BS6 utilizing soybean oil waste. Int Biodeterior Biodegrad 112:72–79. https://doi.org/10.1016/j.ibiod.2016.05.002
Li Z, Zhang Y, Lin J, Wang W, Li S (2019) High-yield di-rhamnolipid production by Pseudomonas aeruginosa YM4 and its potential application in MEOR. Molecules 24(7):1433. https://doi.org/10.1007/s12010-020-03433-4
Li Y, Gao N, Zhang X, Zhao G, Song X (2021) Sophorolipid production using lignocellulosic biomass by co-culture of several recombinant strains of starmerella bombicola with different heterologous cellulase genes from penicillum oxalicum. Appl Biochem Biotechnol 193(2):377–388. https://doi.org/10.1007/s12010-020-03433-4
Liepins J, Balina K, Soloha R, Berzina I, Lukasa LK, Dace E (2021) Glycolipid biosurfactant production from waste cooking oils by yeast: review of substrates. Prod Prod Ferment 7(3):136. https://doi.org/10.3390/fermentation7030136
Liu J, Chen Y, Xu R, Jia Y (2013) Screening and evaluation of biosurfactant-producing strains isolated from oilfield wastewater. Indian J Microbiol 53(2):168–174. https://doi.org/10.1007/s12088-013-0379-y
Liu Q, Lin J, Wang W, Huang H, Li S (2015) Production of surfactin isoforms by Bacillus subtilis BS-37 and its applicability to enhanced oil recovery under laboratory conditions. Biochem Eng J 93:31–37. https://doi.org/10.1016/j.bej.2014.08.023
Liu K, Sun Y, Cao M, Wang J, Lu JR, Xu H (2020) Rational design, properties, and applications of biosurfactants: a short review of recent advances. Curr Opin Colloid Interface Sci 45:57–67. https://doi.org/10.1016/j.cocis.2019.12.005
Luft L, Confortin TC, Todero I, Zabot GL, Mazutti MA (2020) An overview of fungal biopolymers: bioemulsifiers and biosurfactants compounds production. Crit Rev Biotechnol 40(8):1059–1080. https://doi.org/10.1080/07388551.2020.1805405
Luo Z, Yuan XZ, Zhong H, Zeng GM, Liu Z, Ma XL, Zhu Y (2013) Optimizing rhamnolipid production by Pseudomonas aeruginosa ATCC 9027 grown on waste frying oil using response surface method and batch-fed fermentation. J Cent South Univ 20(4):1015–1021. https://doi.org/10.1007/s11771-013-1578-8
Maddikeri GL, Gogate PR, Pandit AB (2015) Improved synthesis of sophorolipids from waste cooking oil using fed batch approach in the presence of ultrasound. Chem Eng J 263:479–487. https://doi.org/10.1016/j.cej.2014.11.010
Madsen JK, Pihl R, Møller AH, Madsen AT, Otzen DE, Andersen KK (2015) The anionic biosurfactant rhamnolipid does not denature industrial enzymes. Front Microbiol 6:292. https://doi.org/10.3389/fmicb.2015.00292
Mani P, Dineshkumar G, Jayaseelan T, Deepalakshmi K, Kumar CG, Balan SS (2016) Antimicrobial activities of a promising glycolipid biosurfactant from a novel marine Staphylococcus saprophyticus SBPS. 3 Biotech. 6(2):1–9. https://doi.org/10.1007/s13205-016-0478-7
Mani P, Sivakumar P, Balan SS (2016b) Economic production and oil recovery efficiency of a lipopeptide biosurfactant from a novel marine bacterium Bacillus simplex. Achiev Life Sci 10(1):102–110. https://doi.org/10.1016/j.als.2016.05.010
Mao X, Jiang R, Xiao W, Yu J (2015) Use of surfactants for the remediation of contaminated soils: a review. J Hazard Mater 285:419–435. https://doi.org/10.1016/j.jhazmat.2014.12.009
Marcelino P, Peres G, Terán-Hilares R, Pagnocca F, Rosa C, Lacerda T, dos Santos J, da Silva S (2019) Biosurfactants production by yeasts using sugarcane bagasse hemicellulosic hydrolysate as new sustainable alternative for lignocellulosic biorefineries. Ind Crops Prod 129:212–223. https://doi.org/10.1016/j.indcrop.2018.12.001
Marchant R, Banat IM (2012) Biosurfactants: a sustainable replacement for chemical surfactants? Biotechnol Lett 34(9):1597–1605. https://doi.org/10.1007/s10529-012-0956-x
Marchut-Mikolajczyk O, Drożdżyński P, Pietrzyk D, Antczak T (2018) Biosurfactant production and hydrocarbon degradation activity of endophytic bacteria isolated from Chelidonium majus L. Microb Cell Factories 17(1):1–9. https://doi.org/10.1186/s12934-018-1017-5
Markande AR, Patel D, Varjani S (2021) A review on biosurfactants: properties, applications and current developments. Bioresour Technol 330:124963. https://doi.org/10.1016/j.biortech.2021.124963
Mawani J, Jadhav J, Pratap A (2021) Fermentative production of mannosylerythritol lipids using sweetwater as waste substrate by Pseudozyma antarctica (MTCC 2706). Tenside Surfactants Deterg 58:246–258. https://doi.org/10.1515/tsd-2020-2272
Meena KR, Sharma A, Kanwar SS (2020) Antitumoral and antimicrobial activity of surfactin extracted from Bacillus subtilis KLP2015. Int J Pept Res Ther 26(1):423–433. https://doi.org/10.1007/s10989-019-09848-w
Meena KR, Dhiman R, Singh K, Kumar S, Sharma A, Kanwar SS, Mondal R, Das S, Franco OL, Mandal AK (2021) Purification and identification of a surfactin biosurfactant and engine oil degradation by Bacillus velezensis KLP2016. Microb Cell Factories 20(1):1–12. https://doi.org/10.1186/s12934-021-01519-0
Mesbaiah FZ, Eddouaouda K, Badis A, Chebbi A, Hentati D, Sayadi S, Chamkha M (2016) Preliminary characterization of biosurfactant produced by a PAH-degrading Paenibacillus sp under thermophilic conditions. Environ Sci Pollut Res. 23(14):14221–14230. https://doi.org/10.1007/s11356-016-6526-3
Mnif I, Grau-Campistany A, Coronel-León J, Hammami I, Triki MA, Manresa A, Ghribi D (2016) Purification and identification of Bacillus subtilis SPB1 lipopeptide biosurfactant exhibiting antifungal activity against Rhizoctonia bataticola and Rhizoctonia solani. Environ Sci Pollut Res 23(7):6690–6699. https://doi.org/10.1007/s11356-015-5826-3
Morita T, Fukuoka T, Imura T, Kitamoto D (2015) Mannosylerythritol lipids: production and applications. J Oleo Sci 64(2):133–141. https://doi.org/10.5650/jos.ess14185
Mousavi F, Beheshti-Maal K, Massah A (2015) Production of sophorolipid from an identified current yeast, Lachancea thermotolerans BBMCZ7FA20, isolated from honey bee. Curr Microbiol 71(2):303–310. https://doi.org/10.1007/s00284-015-0841-7
Murugesan K, Tesfaye Y, Mahmmud A, Tsegaye E, Getachew T, Argaw Y (2019) A comparative preliminary analysis of selected fruit peel waste fermented solutions impact of shorter fermentation in biosurfactant production J Appl Biotechnol Rep 6(2): 69–72 https://doi.org/10.29252/JABR.06.02.05
Nair AS, Al-Bahry S, Sivakumar N (2020) Co-production of microbial lipids and biosurfactant from waste office paper hydrolysate using a novel strain Bacillus velezensis ASN1. Biomass Convers Biorefin 10(2):383–391. https://doi.org/10.1007/s13399-019-00420-6
Najmi Z, Ebrahimipour G, Franzetti A, Banat IM (2018) In situ downstream strategies for cost-effective bio/surfactant recovery. Biotechnol Appl Biochem 65(4):523–532. https://doi.org/10.1002/bab.1641
Nalini S, Parthasarathi R, Prabudoss V (2016) Production and characterization of lipopeptide from Bacillus cereus SNAU01 under solid state fermentation and its potential application as anti-biofilm agent. Biocatal Agric Biotechnol 5:123–132. https://doi.org/10.1016/j.bcab.2016.01.007
Nalini S, Parthasarathi R, Inbakanadan D (2020) Biosurfactant in food and agricultural application. Environ Biotechnol 2(45):75
Nataraj BH, Ramesh C, Mallappa RH (2021) Characterization of biosurfactants derived from probiotic lactic acid bacteria against methicillin-resistant and sensitive Staphylococcus aureus isolates. LWT. https://doi.org/10.1016/j.lwt.2021.112195
Naughton P, Marchant R, Naughton V, Banat I (2019) Microbial biosurfactants: current trends and applications in agricultural and biomedical industries. J Appl Microbiol 127(1):12–28. https://doi.org/10.1111/jam.14243
Nazareth TC, Zanutto CP, Tripathi L, Juma A, Maass D, de Souza AAU, Guelli Ulson SMDA, Banat IM (2020) The use of low-cost brewery waste product for the production of surfactin as a natural microbial biocide. Biotechnol Rep 28:e00537. https://doi.org/10.1016/j.btre.2020.e00537
Nazareth TC, Zanutto CP, Maass D, de Souza AAU, Guelli Ulson SMDA (2021) A low-cost brewery waste as a carbon source in bio-surfactant production. Bioprocess Biosyst Eng. https://doi.org/10.1007/s00449-021-02602-x
Neto DC, Meira JA, Tiburtius E, Zamora PP, Bugay C, Mitchell DA, Krieger N (2009) Production of rhamnolipids in solid-state cultivation: characterization, downstream processing and application in the cleaning of contaminated soils. Biotechnol J 4(5):748–755. https://doi.org/10.1002/biot.200800325
Niu Y, Fan L, Gu D, Wu J, Chen Q (2017) Characterization, enhancement and modelling of mannosylerythritol lipid production by fungal endophyte Ceriporia lacerate CHZJU. Food Chem 228:610–617. https://doi.org/10.1016/j.foodchem.2017.02.042
O’Neill MK, Piligian BF, Olson CD, Woodruff PJ, Swarts BM (2017) Tailoring trehalose for biomedical and biotechnological applications. Pure Appl Chem 89(9):1223–1249. https://doi.org/10.1515/pac-2016-1025
Pacwa-Płociniczak M, Płaz GA, Piotrowska-Seget Z, Cameotra SS (2011) Environmental applications of biosurfactants: recent advances. Intl j Mol Sci 12(1):633–654. https://doi.org/10.3390/ijms12010633
Panjiar N, Mattam AJ, Jose S, Gandham S, Velankar HR (2020) Valorization of xylose-rich hydrolysate from rice straw, an agroresidue, through biosurfactant production by the soil bacterium Serratia nematodiphila. Sci Total Environ 729:138933. https://doi.org/10.1016/j.scitotenv.2020.138933
Pathak KV, Keharia H (2014) Application of extracellular lipopeptide biosurfactant produced by endophytic Bacillus subtilis isolated from aerial roots of banyan (Ficus benghalensis) in microbially enhanced oil recovery (MEOR). 3 Biotech 4(1):41–48. https://doi.org/10.1007/s13205-013-0119-3
Patowary R, Patowary K, Kalita MC, Deka S (2016) Utilization of paneer whey waste for cost-effective production of rhamnolipid biosurfactant. Appl Biochem Biotechnol 180(3):383–399. https://doi.org/10.1007/s12010-016-2105-9
Perez KJ, Viana JdS, Lopes FC, Pereira JQ, Dos Santos DM, Oliveira JS, Velho RV, Crispim SM, Nicoli JR, Brandelli A (2017) Bacillus spp isolated from puba as a source of biosurfactants and antimicrobial lipopeptides. Front microbial 8:61. https://doi.org/10.3389/fmicb.2017.00061
Perfumo A, Banat IM, Marchant R (2018) Going green and cold: biosurfactants from low-temperature environments to biotechnology applications. Trends Biotechnol 36(3):277–289. https://doi.org/10.1016/j.tibtech.2017.10.016
Piedrahíta-Aguirre CA, Alegre RM (2014) Production of lipopeptide iturin a using novel strain Bacillus iso 1 in a packed bed bioreactor. Biocat Agric Biotechnol 3(2):154–158. https://doi.org/10.1016/j.bcab.2013.11.004
Płaza G, Achal V (2020) Biosurfactants: Eco-friendly and innovative biocides against biocorrosion. Int j Mol Sci 21(6):2152. https://doi.org/10.3390/ijms21062152
Radzuan MN, Banat IM, Winterburn J (2017) Production and characterization of rhamnolipid using palm oil agricultural refinery waste. Bioresour Technol 225:99–105. https://doi.org/10.1016/j.biortech.2016.11.052
Ramnani P, Kumar SS, Gupta R (2005) Concomitant production and downstream processing of alkaline protease and biosurfactant from Bacillus licheniformis RG1: bioformulation as detergent additive. Process Biochem 40(10):3352–3359. https://doi.org/10.1016/j.procbio.2005.03.056
Rana S, Singh J, Wadhawan A, Khanna A, Singh G, Chatterjee M (2021) Evaluation of in vivo toxicity of novel biosurfactant from Candida parapsilosis loaded in PLA-PEG polymeric nanoparticles. J Pharm Sci 110(4):1727–1738. https://doi.org/10.1016/j.xphs.2021.01.004
Rangarajan V, Clarke KG (2016) Towards bacterial lipopeptide products for specific applications—a review of appropriate downstream processing schemes. Process Biochem 51(12):2176–2185. https://doi.org/10.1016/j.procbio.2016.08.026
Rangarajan V, Dhanarajan G, Sen R (2014) Improved performance of cross-flow ultrafiltration for the recovery and purification of Ca2+ conditioned lipopeptides in diafiltration mode of operation. J Membr Sci 454:436–443. https://doi.org/10.1016/j.memsci.2013.12.047
Rau U, Nguyen LA, Roeper H, Koch H, Lang S (2005) Downstream processing of mannosylerythritol lipids produced by Pseudozyma aphidis. Eur j Lipid Sci Technol 107(6):373–380. https://doi.org/10.1002/ejlt.200401122
Ravi A, Nandayipurath VVT, Rajan S, Salim SA, Khalid NK, Aravindakumar CT, Krishnankutty RE (2021) Effect of zinc oxide nanoparticle supplementation on the enhanced production of surfactin and iturin lipopeptides of endophytic Bacillus sp Fcl1 and its ameliorated antifungal activity. Pest Manag Sci 77(2):1035–1041. https://doi.org/10.1002/ps.6118
Ravindran A, Sajayan A, Priyadharshini GB, Selvin J, Kiran GS (2020) Revealing the efficacy of thermostable biosurfactant in heavy metal bioremediation and surface treatment in vegetables. Front Microbiol 11:222. https://doi.org/10.3389/fmicb.2020.00222
Rawat G, Dhasmana A, Kumar V (2020) Biosurfactants: The next generation biomolecules for diverse applications. Environ Sustain. https://doi.org/10.1007/s42398-020-00128-8
Reis R, Pacheco G, Pereira A, Freire D (2013) Biosurfactants: production and applications Biodegradation-life of science 31–61
Roy A (2017) Review on the biosurfactants: properties, types and its applications. J Fundam Renew Energy Appl 8:1–14. https://doi.org/10.4172/2090-4541.1000248
Ruba I, Zain B, Ildikó C (2021) Regulatory status quo and prospects for biosurfactants in pharmaceutical applications. Drug Discov Today. https://doi.org/10.1016/j.drudis.2021.03.029
Rufino RD, de Luna JM, de Campos Takaki GM, Sarubbo LA (2014) Characterization and properties of the biosurfactant produced by Candida lipolytica UCP 0988. Elect J Biotechnol 17(1):34–38. https://doi.org/10.1016/j.ejbt.2013.12.006
Saharan B, Sahu R, Sharma D (2011) A review on biosurfactants: fermentation, current developments and perspectives. J Genet Eng Biotechol 1:1–14
Sahu P, Kaushik KK, Lu T, Dong K (2021) Surfactin: a biosurfactant against breast cancer. In: Microbial Biosurfactants, Springer, pp. 147–157. https://doi.org/10.1007/978-981-15-6607-3_7
Saimmai A, Riansa-Ngawong W, Maneerat S, Dikit P (2020) Application of biosurfactants in the medical field. Walailak J Sci Technol 17(2):154–166
Saini HS, Barragán-Huerta BE, Lebrón-Paler A, Pemberton JE, Vázquez RR, Burns AM, Marron MT, Seliga CJ, Gunatilaka AL, Maier RM (2008) Efficient purification of the biosurfactant viscosin from Pseudomonas libanensis strain M9–3 and its physicochemical and biological properties. J Nat Prod 71(6):1011–1015. https://doi.org/10.1021/np800069u
Sajna KV, Sukumaran RK, Jayamurthy H, Reddy KK, Kanjilal S, Prasad RB, Pandey A (2013) Studies on biosurfactants from Pseudozyma sp. NII 08165 and their potential application as laundry detergent additives. Biochem Eng J 78:85–92. https://doi.org/10.1016/j.bej.2012.12.014
Sajna KV, Sukumaran RK, Gottumukkala LD, Pandey A (2015) Crude oil biodegradation aided by biosurfactants from Pseudozyma sp. NII 08165 or its culture broth. Bioresour Technol 191:133–139. https://doi.org/10.1016/j.biortech.2015.04.126
Sałek K, Euston SR (2019) Sustainable microbial biosurfactants and bioemulsifiers for commercial exploitation. Process Biochem 85:143–155. https://doi.org/10.1016/j.procbio.2019.06.027
Samal K, Das C, Mohanty K (2017) Application of saponin biosurfactant and its recovery in the MEUF process for removal of methyl violet from wastewater. J Environ Manag 203:8–16. https://doi.org/10.1016/j.jenvman.2017.07.073
Santos DKF, Rufino RD, Luna JM, Santos VA, Sarubbo LA (2016) Biosurfactants: multifunctional biomolecules of the 21st century. Int j Mol Sci 17(3):401. https://doi.org/10.3390/ijms17030401
Sarachat T, Pornsunthorntawee O, Chavadej S, Rujiravanit R (2010) Purification and concentration of a rhamnolipid biosurfactant produced by Pseudomonas aeruginosa SP4 using foam fractionation. Bioresour Technol 101(1):324–330. https://doi.org/10.1016/j.biortech.2009.08.012
Sarma H, Prasad MNV (2021) Biosurfactants for a sustainable future: production and applications in the environment and biomedicine. Wiley, Hoboken
Satpute SK, Kulkarni GR, Banpurkar AG, Banat IM, Mone IS, Patil RH, Cameotra SS (2016) Biosurfactant/s from Lactobacilli species: properties, challenges and potential biomedical applications. J Bas Microbiol 56:1140–1158. https://doi.org/10.1002/JOBM.201600143
Schultz J, Rosado AS (2020) Extreme environments: a source of biosurfactants for biotechnological applications. Extremophiles 24(2):189–206. https://doi.org/10.1007/s00792-019-01151-2
Sekhon Randhawa KK, Rahman PK (2014) Rhamnolipid biosurfactants—past, present, and future scenario of global market. Front Microbiol 5:454. https://doi.org/10.3389/fmicb.2014.00454
Sen R, Swaminathan T (2005) Characterization of concentration and purification parameters and operating conditions for the small-scale recovery of surfactin. Process Biochem 40(9):2953–2958. https://doi.org/10.1016/j.procbio.2005.01.014
Shah MUH, Sivapragasam M, Moniruzzaman M, Yusup SB (2016) A comparison of recovery methods of rhamnolipids produced by Pseudomonas aeruginosa. Procedia Eng 148:494–500. https://doi.org/10.1016/j.proeng.2016.06.538
Shaligram NS, Singhal RS (2010) Surfactin–a review on biosynthesis, fermentation, purification and applications. Food Technol Biotechnol. 48(2):119–134
Shekhar S, Sundaramanickam A, Balasubramanian T (2015) Biosurfactant producing microbes and their potential applications: a review. Crit Rev Environ Sci Technol 45(14):1522–1554. https://doi.org/10.1080/10643389.2014.955631
Shen L, Zhu J, Lu J, Gong Q, Jin M, Long X (2019) Isolation and purification of biosurfactant mannosylerythritol lipids from fermentation broth with methanol/water/n-hexane. Sep Purifi Technol 219:1–8. https://doi.org/10.1016/j.seppur.2019.03.009
Shoeb E, Akhlaq F, Badar U, Akhter J, Imtiaz S (2013) Classification and industrial applications of biosurfactants. Acad Res Int 4(3):243
Silveira VAI, Kobayashi RKT, de Oliveira Junior AG, Mantovani MS, Nakazato G, Celligoi MAPC (2021) Antimicrobial effects of sophorolipid in combination with lactic acid against poultry-relevant isolates. Braz J Microbiol. https://doi.org/10.1007/s42770-021-00545-9
Singh AK, Cameotra SS (2013) Efficiency of lipopeptide biosurfactants in removal of petroleum hydrocarbons and heavy metals from contaminated soil. Environ Sci Pollut Res 20(10):7367–7376. https://doi.org/10.1007/s11356-013-1752-4
Singh R, Wagh P, Wadhwani S, Gaidhani S, Kumbhar A, Bellare J, Chopade BA (2013) Synthesis, optimization, and characterization of silver nanoparticles from Acinetobacter calcoaceticus and their enhanced antibacterial activity when combined with antibiotics. Int j Nanomed 8:4277. https://doi.org/10.1111/jam.14057
Singh P, Patil Y, Rale V (2019a) Biosurfactant production: emerging trends and promising strategies. J Appl Microbiol 126(1):2–13. https://doi.org/10.1111/jam.14057
Singh RS, Kaur N, Singh D, Kennedy JF (2019) Investigating aqueous phase separation of pullulan from Aureobasidium pullulans and its characterization. Carbohydr Polym 223:115103. https://doi.org/10.1016/j.carbpol.2019.115103
Sivapathasekaran C, Sen R (2017) Origin, properties, production and purification of microbial surfactants as molecules with immense commercial potential. Tenside Surfactants Deterg 54(2):92–107. https://doi.org/10.3139/113.110482
Slivinski CT, Mallmann E, de Araújo JM, Mitchell DA, Krieger N (2012) Production of surfactin by Bacillus pumilus UFPEDA 448 in solid-state fermentation using a medium based on okara with sugarcane bagasse as a bulking agent. Process Biochem 47(12):1848–1855. https://doi.org/10.1016/j.procbio.2012.06.014
Soares da Silva RdCF, de Almeida DG, Brasileiro PPF, Rufino RD, de Luna JM, Sarubbo LA (2019) Production, formulation and cost estimation of a commercial biosurfactant. Biodegradation. 30(4):191–201. https://doi.org/10.1007/s10532-018-9830-4
Song D, Liang S, Yan L, Shang Y, Wang X (2016) Solubilization of polycyclic aromatic hydrocarbons by single and binary mixed rhamnolipid–sophorolipid biosurfactants. J Environl Qual 45(4):1405–1412. https://doi.org/10.2134/JEQ2015.08.0443
Souza KST, Gudiña EJ, Azevedo Z, de Freitas V, Schwan RF, Rodrigues LR, Dias DR, Teixeira JA (2017) New glycolipid biosurfactants produced by the yeast strain Wickerhamomyces anomalus CCMA 0358. Colloids Surf B Biointerfaces 154:373–382. https://doi.org/10.1016/j.colsurfb.2017.03.041
Srivastava S, Mondal MK, Agrawal SB (2021) Biosurfactants for heavy metal remediation and bioeconomics. Biosurfactants Sustain Future Prod Appl Environ Biomed. https://doi.org/10.1002/9781119671022.ch4
Subsanguan T, Khondee N, Nawavimarn P, Rongsayamanont W, Chen CY, Luepromchai E (2020) Reuse of immobilized weissella cibaria PN3 for long-term production of both extracellular and cell-bound glycolipid biosurfactants. Front Bioeng Biotechnol 8:751. https://doi.org/10.3389/fbioe.2020.00751
Takahashi M, Morita T, Fukuoka T, Imura T, Kitamoto D (2012) Glycolipid biosurfactants, mannosylerythritol lipids, show antioxidant and protective effects against H2O2-induced oxidative stress in cultured human skin fibroblasts. J Oleo Sci 61(8):457–464. https://doi.org/10.5650/jos.61.457
Thavasi R, Banat IM (2018) Downstream processing of microbial biosurfactants. Microbial biosurfactants and their environmental and industrial applications, CRC Press Boca Raton, pp. 12
Tian X, Li Y, Chen Y, Mohsin A, Chu J (2021) System optimization of an embedding protocol to immobilize cells from Candida bombicola to improve the efficiency of sophorolipids production. Bioresour Technol. https://doi.org/10.1016/j.biortech.2021.125700
Tiso T, Ihling N, Kubicki S, Biselli A, Schonhoff A, Bator I, Thies S, Karmainski T, Kruth S, Willenbrink AL (2020) Integration of genetic and process engineering for optimized rhamnolipid production using Pseudomonas putida. Front Bioeng Biotechnol 8:976. https://doi.org/10.3389/fbioe.2020.00976
Vallejo CM, Restrepo MAF, Duque FLG, Díaz JCQ (2021) Production, characterization and kinetic model of biosurfactant produced by lactic acid bacteria. Electron J Biotechnol. https://doi.org/10.1016/j.ejbt.2021.06.001
Varjani SJ, Upasani VN (2017) Critical review on biosurfactant analysis, purification and characterization using rhamnolipid as a model biosurfactant. Bioresour Technol 232:389–397. https://doi.org/10.1016/j.biortech.2017.02.047
Vecino X, Barbosa-Pereira L, Devesa-Rey R, Cruz J, Moldes A (2015a) Optimization of liquid–liquid extraction of biosurfactants from corn steep liquor. Bioprocess Biosyst Eng 38(9):1629–1637. https://doi.org/10.1007/s00449-015-1404-9
Vecino X, Barbosa-Pereira L, Devesa-Rey R, Cruz JM, Moldes AB (2015b) Optimization of extraction conditions and fatty acid characterization of Lactobacillus pentosus cell-bound biosurfactant/bioemulsifier. J Sci Food Agric 95(2):313–320. https://doi.org/10.1002/jsfa.6720
Vilela W, Fonseca S, Fantinatti-Garboggini F, Oliveira V, Nitschke M (2014) Production and properties of a surface-active lipopeptide produced by a new marine Brevibacterium luteolum strain. Appl Biochem Biotechnol 174(6):2245–2256. https://doi.org/10.1007/s12010-014-1208-4
Webera A, Maya A, Zeiner T, Góraka A (2012) Downstream processing of biosurfactants. Chem Eng. https://doi.org/10.3303/CET1227020
White D, Hird L, Ali S (2013) Production and characterization of a trehalolipid biosurfactant produced by the novel marine bacterium Rhodococcus sp PML026 strain. J Appl Microbiol 115(3):744–755. https://doi.org/10.1111/jam.12287
Winterburn J, Russell A, Martin P (2011) Integrated recirculating foam fractionation for the continuous recovery of biosurfactant from fermenters. Biochem Eng J 54(2):132–139. https://doi.org/10.1016/j.bej.2011.02.011
Yang X, Zhu L, Xue C, Chen Y, Qu L, Lu W (2012) Recovery of purified lactonic sophorolipids by spontaneous crystallization during the fermentation of sugarcane molasses with Candida albicans O-13-1. Enzyme Microb Technol 51(6–7):348–353. https://doi.org/10.1016/j.enzmictec.2012.08.002
Yang Z, Zu Y, Zhu J, Jin M, Cui T, Long X (2020) Application of biosurfactant surfactin as a pH-switchable biodemulsifier for efficient oil recovery from waste crude oil. Chemosphere 2401:24946. https://doi.org/10.1016/j.chemosphere.2019.124946
Yaraguppi DA, Bagewadi ZK, Muddapur UM, Mulla SI (2020) Response surface methodology-based optimization of biosurfactant production from isolated Bacillus aryabhattai strain ZDY2. J Pet Explor Prod Technol 10(6):2483–2499. https://doi.org/10.1007/s13202-020-00866-9
Yuan J, Raza W, Huang Q, Shen Q (2012) The ultrasound-assisted extraction and identification of antifungal substances from B amyloliquefaciens strain NJN-6 suppressing Fusarium oxysporum. J Basic Microbiol 52(6):721–730. https://doi.org/10.1002/jobm.201100560
Zhao F, Han S, Zhang Y (2020) Comparative studies on the structural composition, surface/interface activity and application potential of rhamnolipids produced by Pseudomonas aeruginosa using hydrophobic or hydrophilic substrates. Bioresour Technol 295:122269. https://doi.org/10.1016/j.biortech.2019.122269
Zambry NS, Rusly NS, Awang MS, Noh NAM, Yahya ARM (2021) Production of lipopeptide biosurfactant in batch and fed-batch Streptomyces sp PBD-410L cultures growing on palm oil. Bioprocess Biosyst Eng 44(7):1577–1592
Zenati B, Chebbi A, Badis A, Eddouaouda K, Boutoumi H, El Hattab M, Hentati D, Chelbi M, Sayadi S, Chamkha M (2018) A non-toxic microbal surfactant from Marinobacter hydrocarbonoclasticus SdK644 for crude oil solubilization enhancement. Ecotoxicol Environ Saf 154:100–107. https://doi.org/10.1016/j.ecoenv.2018.02.032
Zeng G, Liu Z, Zhong H, Li J, Yuan X, Fu H, Ding Y, Wang J, Zhou M (2011) Effect of monorhamnolipid on the degradation of n-hexadecane by Candida tropicalis and the association with cell surface properties. Appl Microbiol Biotechnol 90(3):1155–1161. https://doi.org/10.1007/s00253-011-3125-6
Zhao F, Jiang H, Sun H, Liu C, Han S, Zhang Y (2019) Production of rhamnolipids with different proportions of mono-rhamnolipids using crude glycerol and a comparison of their application potential for oil recovery from oily sludge. RSC Adv 9(6):2885–2891. https://doi.org/10.1039/C8RA09351B
Zhi Y, Wu Q, Xu Y (2017) Production of surfactin from waste distillers’ grains by co-culture fermentation of two Bacillus amyloliquefaciens strains. Bioresour Technol 235:96–103. https://doi.org/10.1016/j.biortech.2017.03.090
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Venkataraman, S., Rajendran, D.S., Kumar, P.S. et al. Extraction, purification and applications of biosurfactants based on microbial-derived glycolipids and lipopeptides: a review. Environ Chem Lett 20, 949–970 (2022). https://doi.org/10.1007/s10311-021-01336-2
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DOI: https://doi.org/10.1007/s10311-021-01336-2