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Toxic metal health risk by mussel consumption

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Abstract

Seafood is a major dietary food worldwide. However, seafood consumption by humans can induce health risk because seafood may be contaminated by various pollutants. The mussel Mytilus galloprovincialis is widely distributed in the coastal waters of Montenegro, SouthEast Adriatic Sea. Here, Zn, Fe, Cu, Ni, Cd, Pb, As, and Hg contents in M. galloprovincialis from ten sites were analyzed to investigate health risks associated with the consumption of wild and cultivated mussels. Since there is a lack of data on the mussel consumption rate in Montenegro, the amount of mussels that can be ingested weekly over a lifetime with no risk of negative health effects was calculated using provisional tolerable weekly intakes (PTWI). We found that Cd concentrations were the limiting factor for mussels as a food. The weekly consumptions of 0.64–1.2 kg of fresh wild and 0.84–1.2 kg of fresh cultivated mussel would be sufficient to reach the PTWICd, which may result in a risky weekly intake of Cd for long-term exposure. Moreover, weekly intake of 125 g mussels was used to calculate the dietary intake of trace elements by mussel consumption and compared with the prescribed PTWIs. Here, we found that there is no risk for human health for all investigated elements. In this case, the highest Cd level obtained in wild and in cultivated mussels represents 19.8 and 14.9% of the PTWICd, respectively. This is the first study in Montenegro giving an assessment of the health risk from trace elements via the consumption of wild and cultivated M. galloprovincialis.

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References

  • Claisse D, Cossa D, Bretaudeau-Sanjuan J, Touchard G, Bombled B (2001) Methylmercury in molluscs along the French Coast. Mar Pollut Bull 42:329–332

    Article  CAS  Google Scholar 

  • Cullaj A, Lazo P, Duka S (2006) Heavy metals and metallonine levels in mussel samples from the Albanian sea coast, MAP/Med Pol., Biological effects monitoring programme, MAP technical reports serial no. 166, Alessandria, Italy, pp 141–151

  • Deudero S, Box A, March D, Valencia JM, Grau AM, Tintore J, Benedicto J (2007) Temporal trends of metals in benthic invertebrate species from the Balearic Islands, Western Mediterranean. Mar Pollut Bull 54:1545–1558

    Article  CAS  Google Scholar 

  • EC (2006) Commission regulation (EC) no 188/2006. Off J Eur Union. 31/11, 2006

  • FAO (2007) National aquaculture sector overview. Montenegro. In: FAO Fisheries and Aquaculture Department [online]. Rome. Available via http://193.43.36.238:8282/fi/website/FIRetrieveAction.do?dom=countrysector&xml=naso_montenegro.xml&lang=en. Accessed 1 Apr 2011

  • FAO (2010) FAO Fisheries and Aquaculture Department, The State of World Fisheries and Aquaculture 2010. Food and agriculture organization of the United Nations, Rome, 2010. Available via http://www.fao.org/docrep/013/i1820e/i1820e.pdf

  • FAO/WHO (2004) Summary of evaluations performed by the joint FAO/WHO expert committee on food additives (JECFA 1956–2003). ILSI Press International Life Sciences Institute, Washington

    Google Scholar 

  • FAO/WHO (2007) Summary of evaluations performed by the joint FAO/WHO expert committee on food additives (JECFA 1956–2007) (first through 68th meetings). Food and Agriculture Organization of the United Nations and the World Health Organization. ILSI Press International Life Sciences Institute, Washington

    Google Scholar 

  • FAO/WHO (2010) Joint FAO/WHO expert committee on food additives. Seventy-third meeting, Geneva, 8–17 June 2010

  • Fattorini D, Notti A, Di Mento R, Cicero AM, Gabellini M, Russo A, Regoli F (2008) Seasonal, spatial and inter-annual variations of trace metals in mussels from the Adriatic sea: a regional gradient for arsenic and implications for monitoring the impact of off-shore activities. Chemosphere 72:1524–1533

    Article  CAS  Google Scholar 

  • Gorell JM, Johnson CC, Rybicki BA, Peterson EL, Kortsha GX, Brown GG (1997) Occupational exposures to metals as risk factors for Parkinson’s disease. Neurology 48:650–658

    CAS  Google Scholar 

  • Gosling E (1992) Genetics of Mytilus. In: Gosling E (ed) The mussel Mytilus: ecology, physiology genetics and culture. Elsevier, Amsterdam, pp 309–382

    Google Scholar 

  • Goyer RA (1995) Nutrition and metal toxicity. Am J Clin Nutr 61:646–650

    Google Scholar 

  • ICES (2008) Report of the joint ICES/CIESM workshop to compare zooplankton ecology and methodologies between the Mediterranean and the North Atlantic (WKZEM), Heraklion, Crete, Greece

  • Järup L (2003) Hazards of heavy metal contamination. Br Med Bull 68:167–182

    Article  Google Scholar 

  • Jovic M, Stankovic A, Slavkovic-Beskoski L, Tomic I, Degetto S, Stankovic S (2011) Mussels as a bio-indicator of the environmental quality of the coastal water of the Boka Kotorska Bay (Montenegro). J Serb Chem Soc 76:933–946

    Article  CAS  Google Scholar 

  • Kljakovic-Gaspic Z, Ujevic I, Zvonaric T, Baric A (2007) Biomonitoring of trace metals (Cu, Cd, Cr, Hg, Pb, Zn) in Mali Ston Bay (eastern Adriatic) using the Mediterranean blue mussel (1998–2005). Acta Adriat 48:73–88

    Google Scholar 

  • Malik N, Biswas AK, Qureshi TA, Borana K, Virha R (2010) Bioaccumulation of heavy metals in fish tissues of a freshwater lake of Bhopal. Environ Monit Assess 160:267–276

    Article  CAS  Google Scholar 

  • Mikac N, Kwokal Z, Martincic D, Branica M (1996) Uptake of mercury species by transplanted mussels Mytilus galloprovincialis under estuarine conditions (Krka River estuary). Sci Total Environ 184:173–182

    Article  CAS  Google Scholar 

  • Nagajyoti PC, Lee KD, Sreekanth TVM (2010) Heavy metals, occurrence and toxicity for plants: a review. Environ Chem Lett 8:199–216

    Article  CAS  Google Scholar 

  • Nasreddine L, Nashalian O, Naja F, Itani L, Parent-Massin D, Nabhani-Zeidan M, Hwalla N (2010) Dietary exposure to essential and toxic trace elements from a total diet study in an adult Lebanese urban population. Food Chem Toxicol 48:1262–1269

    Article  CAS  Google Scholar 

  • National Academy of Sciences (NAS) (2001) Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium and zinc. National Academy Press, Washington. http://books.nap.edu/books/0309072794/html/index.html

  • Ozden O, Ulusoy S, Erkan N (2010) Study on the behavior of the trace metal and macro minerals in Mytilus galloprovincialis as a bioindicator species: the case of Marmara Sea, Turkey. J Verbr Lebensm 5:407–412

    Article  Google Scholar 

  • Plum LM, Rink L, Haase H (2010) The essential toxin: impact of zinc on human health. Int J Environ Res Public Health 7:1342–1365

    Article  CAS  Google Scholar 

  • Regulation MontenegrinFood (2002) Legislation on maximum permitted level of pesticides, heavy metals and other toxic substances, hormones, antibiotics and mycotoxins in food. Sluzbeni list SRJ 5:67–85

    Google Scholar 

  • Scancar J, Zuliani T, Turk T, Milacic R (2007) Organotin compounds and selected metals in the marine environment of Northern Adriatic Sea. Environ Monit Assess 127:271–282

    Article  CAS  Google Scholar 

  • Shiomi K (1994) Arsenic in marine organisms: chemical forms and toxicological aspects. In: Nriagu J (ed) Arsenic in the environment. Part II: human health and ecosystem effects. Wiley, New York, pp 261–282

    Google Scholar 

  • Simonič M (2009) Removal of inorganic As5+ from a small drinking water system. J Serb Chem Soc 74:85–92

    Article  Google Scholar 

  • Sivaperumal P, Sankar TV, Viswanathan Nair PG (2007) Heavy metal concentrations in fish, shellfish and fish products from internal markets of India vis-à-vis international standards. Food Chem 102:612–620

    Article  CAS  Google Scholar 

  • Smaal AC (2002) European mussel cultivation along the Atlantic coast: production status, problems and perspectives. Hydrobiologia 484:89–98

    Article  Google Scholar 

  • Stankovic S, Jovic M, Stankovic AR, Katsikas L (2011) Heavy metals in seafood mussels. Risk for human health. In: Lichtfouse E, Schwarzbauer J, Robert D (eds) Environmental chemistry, vol 2. Springer, Netherlands (in press)

  • Subasinghe R, Soto D, Jia J (2009) Global aquaculture and its role in sustainable development. Rev Aquac 1:2–9

    Article  Google Scholar 

  • USFDA (2007) Guide for the control of molluscan shellfish 2007-guidance documents chapter II. Growing areas: 04. Action levels, tolerances and guidance levels for poisonous or deleterious substances in seafood, pp 1–4

  • Uthus EO (1997) Dietary nickel and folic acid interact to affect folate and methionine metabolism in the rat. Biol Trace Elem Res 58:25–33

    Article  CAS  Google Scholar 

  • Whyte ALH, Raumati Hook G, Greening GE, Gibbs-Smith E, Gardner JPA (2009) Human dietary exposure to heavy metals via the consumption of greenshell mussels (Perna canaliculus Gmelin 1791) from the Bay of Islands, northern New Zealand. Sci Total Environ 407:4348–4355

    Article  CAS  Google Scholar 

Download references

Acknowledgments

This research was financed by the Ministry of Science and Technological Development of the Republic of Serbia, Contract No. III43009.

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Authors and Affiliations

  1. Vinca Institute of Nuclear Sciences, University of Belgrade, P. O. Box 522, 11001, Belgrade, Serbia

    Mihajlo Jović & Antonije Onjia

  2. Faculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, 11000, Belgrade, Serbia

    Slavka Stanković

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  1. Mihajlo Jović
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  2. Antonije Onjia
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  3. Slavka Stanković
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Correspondence to Slavka Stanković.

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Jović, M., Onjia, A. & Stanković, S. Toxic metal health risk by mussel consumption. Environ Chem Lett 10, 69–77 (2012). https://doi.org/10.1007/s10311-011-0330-6

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  • DOI: https://doi.org/10.1007/s10311-011-0330-6

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