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Significance of flavonoids in plant resistance: a review

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References

  • Agrawal GK, Rakwal R, Tamogami S, Yonekura M, Kubo A, Saji H (2002) Chitosan activates defense/stress response(s) in the leaves of Oryza sativa seedlings. Plant Physiol Biochem 40:1061–1069

    CAS  Google Scholar 

  • Aguero ME, Gevens A, Nicholson RL (2002) Interaction of Cochliobolus heterostrophus with phytoalexin inclusions in Sorghum bicolor. PMPP 61:267–271

    Google Scholar 

  • Alcerito T, Barbo FE, Negri G, Santos DYAC, Meda CI, Young MCM, Chávez D, Blatt CTT (2002) Foliar epicuticular wax of Arrabidea brachypoda: flavonoids and antifungal activity. Biochem Systemat Ecol 30:677–683

    CAS  Google Scholar 

  • Arcas MC, Botía JM, Ortuño AM, Del Rio JA (2000) UV irradiation alters the levels of flavonoids involved in the defence mechanism of Citrus aurantium fruits against Peniillium digitatum. Eur J Plant Pathol 106:617–622

    CAS  Google Scholar 

  • Awad M, DeJager A (2002) Relationships between fruit nutrients and concentrations of flavonoids and chlorogenic acid in ‘Elstar’ apple skin. Sci Hortic 92:265–276

    CAS  Google Scholar 

  • Bais HP, Vepachedu R, Gilroy S, Callaway RM, Vivanco JM (2003) Allelopathy and exotic plant invasion: from molecules and genes to species interaction. Science 301:1377–1380

    CAS  Google Scholar 

  • Barceló J, Poschenrieder C (2002) Fast root growth responses, root exudates, and internal detoxification as clues to the mechanism of aluminium toxicity and resistance: a review. Environ Exp Bot 48:75–92

    Google Scholar 

  • Barry KM, Davies NW, Mohammed CL (2002) Effect of season and different fungi on phenolics in response to xylem wounding and inoculation in Eucalyptus nitens. For Path 32:163–178

    Article  Google Scholar 

  • Baur R, Haribal M, Renwick AA, Städler E (1998) Contact chemoreception related to host selection and oviposition behaviour in the monarch butterfly, Danaus plexippus. Physiol Entomol 23:7–19

    CAS  Google Scholar 

  • Bazzaz FA (1987) Allocation of resources in plants: State of the science and critical questions. In: Bazzaz FA, Grace J (eds) Plant resource allocation. Academic Press, San Diego, pp 1–38

    Google Scholar 

  • Bazzi C, Messina C, Tortoreto L, Stefani E, Bini F, Brunelli A, Andreotti C, Sabatini E, Spinelli F, Costa G, Hauptmann S, Stammler G, Doerr S, Marr J, Rademacher W (2003) Control of pathogen incidence in pome fruits and other horticultural crop plants with prohexadione-Ca. Eur J Hort Sci 68:108–114

    CAS  Google Scholar 

  • Beckman CH (2000) Phenolic-storing cells: keys to programmed cell death and periderm formation in wilt disease resistance and in general defence responses in plants? PMPP 57:101–110

    CAS  Google Scholar 

  • Benoit LF, Berry AM (1997) Flavonoid-like compounds from seeds of red alder (Alnus rubra) influence host nodulation by Frankia (Actinomycetales). Physiol Plant 99:588–593

    CAS  Google Scholar 

  • Berhow MA, Vaughn SF (1999) Higher plant flavonoids: biosynthesis and chemical ecology. In: Inderjit, Dakshini KMM, Foy CL (eds) Principles and practices in plant ecology. CRC Press, Boca Raton, pp 423–438

    Google Scholar 

  • Brignolas F, Lieutier F, Sauvard D, Christiansen E, Berryman AA (1998) Phenolic predictors for Norway spruce resistance to the bark beetle Ips typographus (Coleoptera: Scolytidae) and an associated fungus, Ceratocystis polonica. Can J For Res 28:720–728

    CAS  Google Scholar 

  • Broughton WJ, Zhang F, Perret X, Staehelin (2003) Signals exchanged between legumes and Rhizobium: agricultural uses and perspectives. Plant Soil 252:129–137

    CAS  Google Scholar 

  • Bryant J, Chapin IF, Klein D (1983) Carbon/nutrient balance of boreal plants in relation to vertebrate herbivory. Oikos 40:357–368

    CAS  Google Scholar 

  • Chalker-Scott L, Krahmer RL (1989) Microscopic studies of tannin formation and distribution in plant tissues. In: Hemingway RW, Karchesy JJ (eds) Chemistry and significance of condensed tannins, Plenum Press, New York, pp 345–368

    Google Scholar 

  • Chaves N, Escudero JC (1999) Variation of flavonoid synthesis induced by ecological factors. In: Inderjit, Dakshini KMM, Foy CL (eds) Principles and practices in plant ecology. CRC Press, Boca Raton, pp 267–285

    Google Scholar 

  • Chen K, Ohmura W, Doi S, Aoyama M (2004) Termite feeding deterrent from Japanese larch wood. Bioresource Technol 95:129–134

    CAS  Google Scholar 

  • Chou C-H (1999) Roles of allelopathy in plant biodiversity and sustainable agriculture. Crit Rev Plant Sci 18:609–636

    Google Scholar 

  • Close DC, McArthur C (2002) Rethinking the role of many plant phenolics—protection from photodamage not herbivores? Oikos 99:166–172

    CAS  Google Scholar 

  • Cohen MF, Yamaseki H (2000) Flavonoid-induced expression of a symbiosis-related gene in the cyanobacterium Nostoc punctiforme. J Bacteriol 182:4644–4646

    CAS  Google Scholar 

  • Coley PD, Bryant JP, Chapin FS (1985) Resource availability and plant antiherbivore defense. Science 230:895–899

    Google Scholar 

  • Collingborn FMB, Gowen SR, Mueller-Harvey I (2000) Investigations into the biochemical basis of nematode resistance in roots of three Musa cultivars in response to Radopholus similis infection. J Agric Food Chem 48:5297–5301

    CAS  Google Scholar 

  • Cooper JE (2004) Dominant role of flavonoids among signal molecules involved in the formation of legume-rhizobia symbiosis. Polyphenol Commun 2004:87

    Google Scholar 

  • Cuadra P, Harborne JB, Waterman PG (1997) Increases in surface flavonols and photosynthetic pigments in Gnaphalium luteo-album in response to UV-B radiation. Phytochemistry 45:1377–1383

    CAS  Google Scholar 

  • Davies KM, Schwinn KE, Deroles SC, Manson DG, Lewis DH, Bloor SJ, Bradley JM (2003) Enhancing anthocyanin production by altering competition for substrate between flavonol synthase and dihydroflavonol 4-reductase. Euphytica 131:259–268

    CAS  Google Scholar 

  • DeBruyne T, Pieters L, Deelstra H, Vlietinck A (1999) Condensed vegetable tannins: biodiversity in structure and biology activities. Biochem Systemat Ecol 27:445–459

    CAS  Google Scholar 

  • Del Rio JA, Arcas MC, Botía JM, Baídez AG, Fuster MD, Ortuño A (2000) Involvement of phenolic compounds in the antifungal defense mechanisms of Olea europaea L. and Citrus sp. Recent Res Dev Agric Food Chem 4:331–341

    CAS  Google Scholar 

  • Del Rio JA, Gonzalez A, Fuster MD, Botia JM, Gomez P, Frias V, Ortuño A (2001) Tylose formation and changes in phenolic compounds of grape roots infected with Phaeomoniella chlamydospora and Phaeoacremonium species. Phytopathol Mediterr 40(Suppl):S394–S399

    CAS  Google Scholar 

  • Del Rio JA, Báidez AG, Botía JM, Ortuño A (2003) Enhancement of phenolic compounds in olive plants (Olea europaea L.) and their influence on resistance against Phytophthora sp. Food Chem 83:75–78

    CAS  Google Scholar 

  • Deng F, Aoki M, Yogo Y (2004) Effect of naringenin on the growth and lignin biosynthesis of gramoineous plants. Weed Biol Manag 4:49–55

    CAS  Google Scholar 

  • Dixon RA, Steel CL (1999) Flavonoids and isoflavonoids—a gold mine for metabolic engineering. Trends Plant Sci 4:394–400

    Google Scholar 

  • Estiarte M, Peñuelas J, Kimball BA, Hendrix DL, Pinter PJJR, Wall GW, LaMorte RL, Hunsaker D (1999) Free-air CO2 enrichment of wheat: leaf flavonoid concentration throughout the growth cycle. Physiol Plant 105:423–433

    CAS  Google Scholar 

  • Eyles A, Davies NW, Yuan ZQ, Mohammed C (2003) Host response to natural infection by Cytonaema sp. in the aerial bark of Eucalyptus globulus. For Pathol 33:317–331

    Google Scholar 

  • Farooq A, Tahara S (1999) Fungal metabolism of flavonoids and related phytoalexins. Curr Topics Phytochem 2:1–33

    CAS  Google Scholar 

  • Feeny PP (1976) Plant apparancy and chemical defense. Rec Adv Phytochem 10:1–40

    CAS  Google Scholar 

  • Feild TS, Lee DW, Holbrook NM (2001) Why leaves turn red in autumn. The role of anthocyanins in senescing leaves of Red-Osier Dogwood. Plant Physiol 127:566–574

    CAS  Google Scholar 

  • Feucht W, Treutter D (1999) The role of flavan-3-ols and proanthocyanidins in plant defence. In: Inderjit S, Dakshini KMM, Foy CL (eds) Principles and practices in plant ecology. CRC Press, Boca Raton, pp 307–338

    Google Scholar 

  • Feucht W, Treutter D, Polster J (2004) Flavanol binding of nuclei from tree species. Plant Cell Rep 22:430–436

    CAS  Google Scholar 

  • Fischbach RJ, Kossmann B, Panten H, Steinbrecher R, Heller W, Seidlitz HK, Sandermann H, Hertkorn N, Schnitzler J-P (1999) Seasonal accumulation of ultraviolet-B screening pigments in needles of Norway spruce (Picea abies (L.) Karst.). Plant Cell Environ 22:27–37

    CAS  Google Scholar 

  • Fofana B, McNally DJ, Labbé C, Boulanger R, Benhamou N, Séguin A, Bélanger RR (2002) Milsana-induced resistance in powdery mildew-infected cucumber plants correlates with the induction of chalcone synthase and chalcone isomerase. PMPP 61:121–132

    CAS  Google Scholar 

  • Forkner RE, Marquis RJ, Lill JT (2004) Feeny revisited: condensed tannins as anti-herbivore defences in leaf-chewing herbivore communities of Quercus. Ecol Entomol 29:174–187

    Google Scholar 

  • Gallet C, Després L, Tollenaere C (2004) Phenolic response of Trollius europaeus to Chiastocheta invasion. Polyphenol Commun 2004:759–760

    Google Scholar 

  • Gandikota M, DeKochko A, Chen L, Ithal N, Fauquet C, Reddy AR (2001) Development of transgenic rice plants expressing maize anthocyanin genes and increased blast resistance. Mol Breed 7:73–83

    CAS  Google Scholar 

  • Gayler S, Leser C, Priesack E, Treutter D (2004) Modelling the effect of environmental factors on the “trade-off” between growth and defensive compounds in young apple trees. Trees 18:363–371

    Google Scholar 

  • Gould KS, Mickelvie J, Markham KR (2002) Do anthocyanins function as antioxidants in leaves? Imaging of H2O2 in red and green leaves after mechanical injury. Plant Cell Environ 25:2161–1269

    Google Scholar 

  • Grayer RJ, Harborne JB (1994) A survey of antifungal compounds from higher plants, 1982–1993. Phytochemistry 37:19–42

    CAS  Google Scholar 

  • Hada H, Hidema J, Maekawa M, Kumagai T (2003) Higher amounts of anthocyanins and UV-absorbing compounds effectively lowered CPD photorepair in purple rice (Oryza sativa L.). Plant Cell Environ 26:1691–1701

    CAS  Google Scholar 

  • Halbwirth H, Fischer TC, Roemmelt S, Spinelli F, Schlangen K, Peterek S, Sabatini E, Messina C, Speakman J-B, Andreotti C, Rademacher W, Bazzi C, Costa G, Treutter D, Forkmann G, Stich K (2003) Induction of antimicrobial 3-deoxyflavonoids in pome fruit trees controls fire blight. Z Naturforsch 58c:765–770

    Google Scholar 

  • Hammerschmidt R (1999) Phytoalexins: what have we learned after 60 years? Annu Rev Phytopathol 37:285–306

    CAS  Google Scholar 

  • Harborne JB (1994) Plant polyphenols and their role in plant defence mechanisms. In: Brouillard R, Jay M, Scalbert A (eds) Polyphenols, vol. 94, pp 19–26

  • Haribal M, Feeny P (2003) Combined roles of contact stimulant and deterrents in assessment of host-plant quality by ovipositing zebra swallowtail butterflies. J Chem Ecol 29:653–670

    CAS  Google Scholar 

  • Harrison MJ, Dixon RA (1994) Spatial pattern of expression of flavonoid/isoflavonoid pathway genes during interactions between roots of Medicago trunculata and the mycorrhizal fungus Glomus versiforme. Plant J 6:9–20

    CAS  Google Scholar 

  • Heil M, Delsinne T, Hilpert A, Schürkens S, Andary C, Linsenmair KE, Sousa M, McKey D (2002) Reduced chemical defence in ant-plants? A critical re-evaluation of a widely accepted hypothesis. Oikos 99:457–468

    CAS  Google Scholar 

  • Herms DA, Mattson WJ (1992) The dilemma of plants: to grow or defend. Quart Rev Biol 67:283–335

    Google Scholar 

  • Hoffmann-Campo CB, Harborne JB, McCaffery AR (2001) Pre-ingestive and post-ingestive effects of soya bean extracts and rutin on Trichoplusia ni growth. Entomol Exp Appl 98:181–194

    Google Scholar 

  • Hungria M, Stacey G (1997) Molecular signals exchanged between host plants and rhizobia: basic aspects and potential application in agriculture. Soil Biol Biochem 29:819–830

    CAS  Google Scholar 

  • Inderjit, Gross E (2000) Plant phenolics: potential role in aquatic and terrestrial ecosystems. In: Martens S, Treutter D, Forkmann G (eds) Polypenols, pp 206–234

  • Jansen MAK (2002) Ultraviolet-B radiation effects on plants: induction of morphogenic responses. Physiol Plant 116:423–429

    CAS  Google Scholar 

  • Ju Z, Bramlage WJ (1999) Phenolics and lipid-soluble antioxidants in fruit cuticle of apples and their antioxidant activities in model systems. Postharvest Biol Technol 16:107–118

    CAS  Google Scholar 

  • Kangatharalingam N, Pierce ML, Bayles MB, Essenberg M (2002) Epidermal anthocyanin production as an indicator of bacterial blight resistance in cotton. PMPP 61:189–195

    CAS  Google Scholar 

  • Keller M, Rogiers SY, Schultz HR (2003) Nitrogen and ultraviolett radiation modify grapevines’ susceptibility to powdery mildew. Vitis 42:87–94

    CAS  Google Scholar 

  • Keller M, Viret O, Cole FM (2003) Botrytis cinerea infection in grape flowers: defense reaction, latency, and disease expression. Phytopathology 93:316–322

    Google Scholar 

  • Kobayashi H, Naciri-Graven Y, Broughton WJ, Perret X (2004) Flavonoids induce temporal shifts in gene-expression of nod-box controlled loci in Rhizobium sp. NGR234. Mol Microbiol 51:335–347

    CAS  Google Scholar 

  • Kolb CA, Käser MA, Kopecký J, Zotz G, Riederer M, Pfündel EE (2001) Effects of natural intensities of visible and ultraviolet radiation on epidermal ultraviolet screening and photosynthesis in grape leaves. Plant Physiol 127:863–875

    CAS  Google Scholar 

  • Kong J-M, Chia L-S, Goh N-K, Chia T-F, Brouillard R (2003) Analysis and biological activities of anthocyanins. Phytochemistry 64:923–933

    CAS  Google Scholar 

  • Kuc J (1994) Relevance of phytoalexins—a critical review. In: Geibel M, Treutter D, Feucht W (eds) Natural phenols in plant resistance. Acta Horticult 381:526–539

    CAS  Google Scholar 

  • Lagrange H, Jay-Allemand C, Lapeyrie F (2001) Rutin, the phenolglycoside from eucalyptus root exudates, stimulates Pisolithus hyphal growth at picomolar concentrations. New Phytol 149:349–355

    CAS  Google Scholar 

  • Laitinen M-L, Julkunen-Tiitto R, Yamaji K, Heinonen J, Rousi M (2004) Variation in birch bark secondary chemistry between and within clones: implications for herbivory to hares. Oikos 104:316–326

    CAS  Google Scholar 

  • Lattanzio V, Cardinali A, Palmieri S (1994) The role of phenolics in the potsharvest physiology of fruits and vegetables: browning reactions and fungal diseases. Ital J Food Sci 1:3–22

    Google Scholar 

  • Lattanzio V (2003) Bioactive polyphenols: their role in quality and storability of fruit and vegetables. J Appl Bot 77:128–146

    CAS  Google Scholar 

  • Lavola A, Julkunen-Tiitto R, Roininen H, Aphalo P (1998) Host-plant preference of an insect herbivore mediated by UV-B and CO2 in relation to plant secondary metabolites. Biochem Syst Ecol 26:1–12

    CAS  Google Scholar 

  • Leser C, Treutter D (2005) Effects of nitrogen supply on growth, contents of phenolic compounds and pathogen (scab) resistance of apple trees. Physiol Plant 123:49–56

    CAS  Google Scholar 

  • Lo S-CC, DeVerdier K, Nicholson RL (1999) Accumulation of 3-deoxyanthocyanidin phytoalexins and resistance to Colletotichum sublineolum in sorghum. PMPP 55:263–273

    CAS  Google Scholar 

  • Loomis WE (1953) Growth and differentiation. In: Loomis WE (ed) Growth and differentiation in plants. Iowa State College Press, Ames, pp 1–17

    Google Scholar 

  • Mallikarjuna N, Kranthi KR, Jadhav DR, Kranthi S, Chandra S (2004) Influence of foliar chemical compounds on the development of Spodoptera litura (Fab.) in interspecific derivatives of groundnut. J Appl Entomol 128:321–328

    CAS  Google Scholar 

  • Manthey JA, Grohmann K, Berhow MA, Tisserat B (2000) Changes in citrus leaf flavonoid concentrations resulting from blight-induced zinc-deficiency. Plant Physiol Biochem 38:333–343

    CAS  Google Scholar 

  • Mathesius U (2003) Conservation and divergence of signalling pathways between roots and soil microbes—the Rhizobium-legume symbiosis compared to the development of lateral roots, mycorrhizal interactions and nematode-induced galls. Plant Soil 255:105–119

    CAS  Google Scholar 

  • Mathesius U, Schlamann HRM, Spaink HP, Sautter C, Rolfe BC, Djordjevic MA (1998) Auxin transport inhibition precedes root nodule formation in white clover roots and is regulated by flavonoids and derivatives of chitin oligosaccharides. Plant J 14:23–24

    CAS  Google Scholar 

  • Mattson WJ, Kuokkanen K, Niemelä P, Julkunen-Tiitto R, Kellomäki S, Tahvanainen J (2004) Elevated CO2 alters birch resistance to Lagomorpha herbivores. Global Change Biol 10:1402–1413

    Google Scholar 

  • Matyssek R, Schnyder H, Elstner EF, Munch JC, Pretzsch H, Sandermann H (2002) Growth and parasite defence in plants; the balance between resource sequestration and retention: in lieu of a guest editorial. Plant Biol 4:133–136

    Google Scholar 

  • Mayr U, Michalek S, Treutter D, Feucht W (1997) Phenolic compounds of apple and their relationship to scab resistance. J Phytopathol 145:69–75

    CAS  Google Scholar 

  • Mayr U, Treutter D (1998) Flavanols as defence barriers in apple leaves against the apple scab fungus (Venturia inaequalis). Acta Hort 456:79–82

    Google Scholar 

  • McNally DJ, Wurms KV, Labbé C, Bélanger RR (2003) Synthesis of C-glycosyl flavonoid phytoalexins as a site-specific response to fungal penetration in cucumber. PMPP 63:293–303

    CAS  Google Scholar 

  • Marles MAS, Ray H, Gruber MY (2003) New perspectives on proanthocyanidin biochemistry and molecular regulation. Phytochemistry 64:367–383

    CAS  Google Scholar 

  • Merzylak MN, Solovchenko AE, Chivkunova OB (2002) Patterns of pigment changes in apple fruits during adaptation to high sunlight and sunscald development. Plant Physiol Biochem 40:679–684

    Google Scholar 

  • Mo YY, Geibel M, Bonsall RF, Gross DC (1995) Analysis of sweet cherry (Prunus avium L.) leaves for plant signal molecules that activate the syrB gene required for synthesis of the phytotoxin, syringomycin, by Pseudomonas syringae pv. syringae. Plant Physiol 107:603–612

    CAS  Google Scholar 

  • Moore JP, Westall KL, Ravenscroft N, Farrant JM, Lindsey GG, Brandt WF (2004) The predominant polyphenol in the leaves of the ressurrection plant Myrothamnus flabellifolius, 3,4,5 tri-O-galloylquinic acid, protects membranes against desiccation and free radical induced oxidation. Polyphenol Commun 2004:79

    Google Scholar 

  • Murphy A, Peer WA, Taiz L (2000) Regulation of auxin transport by aminopeptidases and endogenous flavonoids. Planta 211:315–324

    CAS  Google Scholar 

  • Nicholson RL, Hammerschmidt R (1992) Phenolic compounds and their role in disease resistance. Annu Rev Phytopathol 30:369–389

    CAS  Google Scholar 

  • Nicholson RL, Wood KV (2001) Phytoalexins and secondary products, where are they and how can we measure them? PMPP 59:63–69

    CAS  Google Scholar 

  • Nielsen K, Deroles SC, Markham KR, Bradley MJ, Podivinsky E, Manson D (2002) Mol Breed 9:217–229

    CAS  Google Scholar 

  • Nikiforova V, Freitag J, Kempa S, Adamik M, Hesse H, Hoefgen R (2003) Transcriptome analysis of sulfur depletion in Arabidopsis thaliana: interlacing of biosynthetic pathways provides response specificity. Plant J 33:633–650

    CAS  Google Scholar 

  • Nykänen H, Koricheva J (2004) Damage-induced changes in woody plants and their effects on insect herbivore performance: a meta-analysis. Oikos 104:247–268

    Google Scholar 

  • Padmavati M, Sakthivel N, Thara KV, Reddy AR (1997) Differential sensitivity of rice pathogens to growth inhibition by flavonoids. Phytochemistry 46:499–502

    CAS  Google Scholar 

  • Parr AJ, Bolwell GP (2000) Phenols in the plant and in man. The potential for possible nutritional enhancement of the diet by modifying the phenols content or profile. J Sci Food Agric 80:985–1012

    CAS  Google Scholar 

  • Parvez MM, Tomita-Yokotani K, Fujii Y, Konishi T, Iwashina T (2004) Effects of quercetin and its seven derivatives on the growth of Arabidopsis thaliana and Neurospora crassa. Biochem Syst Ecol 32:631–635

    CAS  Google Scholar 

  • Pietrini F, Iannelli MA, Massacci A (2002) Anthocyanin accumulation in the illuminated surface of maize leaves enhances protection from photo-inhibitory risks at low temperature, without further limitation to photosynthesis. Plant Cell Environ 25:1251–1259

    CAS  Google Scholar 

  • Pizzi A, Cameron FA (1986) Flavonoid tannins—structural wood components for drought-resistant mechanisms of plants. Wood Sci Technol 20:119

    CAS  Google Scholar 

  • Ponce MA, Scervino JM, Erra-Balsells R, Ocampo JA, Godeas AM (2004) Flavonoids from shoots and roots of Trifolium repens (white clover) grown in presence or absence of the arbuscular mycorrhizal fungus Glomus intraradices. Phytochemistry 65:1925–1930

    CAS  Google Scholar 

  • Reuber S, Bornman JF, Weissenböck G (1996) Phenylpropanoid compounds in primary leaf tissues of rye (Secale cereale). Light response of their metabolism and the possible role in UV-B protection. Physiol Plant 97:160–168

    CAS  Google Scholar 

  • Riipi M, Ossipov V, Lempa K. Haukioja E, Koricheva J, Ossipova S, Pihlaja K (2001) Seasonal changes in birch leaf chemistry: are there trade-offs between leaf growth and accumulation of phenolics? Oecologia 130:380–390

    Google Scholar 

  • Römmelt S, Treutter D, Speakman JB, Rademacher W (1999) Effects of prohexadione-Ca on the flavonoid metabolism of apple with respect to plant resistance against fire blight. Acta Hort 489:359–363

    Google Scholar 

  • Roemmelt S, Zimmermann N, Rademacher W, Treutter D (2003) Formation of novel flavonoids in apple (Malus x domestica) treated with the 2-oxoglutarate-dependent dioxygenase inhibitor prohexadione-Ca. Phytochemistry 64:709–716

    CAS  Google Scholar 

  • Rosati C, Simoneau P, Treutter D, Poupard P, Cadot Y, Cadic A, Duron M (2003) Engineering of flower color in forsythia by expression of two independently-transformed dihydroflavonol 4-reductase and anthocyanidin synthase genes of flavonoid pathway. Mol Breed 12:197–208

    CAS  Google Scholar 

  • Rozema J, VanDeStaaij J, Björn LO, Caldwell M (1997) UV-B as an environmental factor in plant life: stress and regulation. Tree 12:22–28

    Google Scholar 

  • Rozema J, Björn LO, Bornman JF, Gaberščik A, Häder D-P, Trošt, Germ M, Klisch M, Gröniger A, Sinha RP, Lebert M, He Y-Y, Buffoni-Hall R, DeBakker NVJ, VanDeStaaij J, Meijkamp BB (2002) The role of UV-B radiation in aquatic and terrestrial ecosystems—an experimental and functional analysis of the evolution of UV-absorbing compounds. J Photochem Photobiol B Biol 66:2–12

    CAS  Google Scholar 

  • Rühmann S, Leser C, Bannert M, Treutter D (2002) Relationship between growth, secondary metabolism, and resistance of apple. Plant Biol 4:137–193

    Google Scholar 

  • Rühmann S, Treutter D (2003) Effect of N-nutrition in apple on the response of its secondary metabolism to prohexadione-Ca treatment. Eur J Hort Sci 68:152–159

    Google Scholar 

  • Ryan KG, Swinny EE, Markham KR, Winefield C (2002) Flavonoid gene expression and UV photoprotection in transgenic and mutant Petunia leaves. Phytochemistry 59:23–32

    CAS  Google Scholar 

  • Sandermann H, Ernst D, Heller W, Langebartels C (1998) Ozone: an abiotic elicitor of plant defence reactions. Trends Plant Sci 3:47–50

    Google Scholar 

  • Schlösser E (1994) Preformed phenols as resistance factors. In: Geibel M, Treutter D, Feucht W (eds) International Symposium on natural phenols in plant resistance. Acta Hortic 381:615–630

  • Schijlen EGWM, Ric de Vos CH, VanTunen AJ, Bovy AG (2004) Modification of flavonoid biosynthesis in crop plants. Phytochemistry, doi: 10.1016/j.phytochem.2004.07.028

  • Shiozaki N, Hattori I, Gojo R, Tezuka T (1999) Activation of growth and nodulation in a symbiotic system between pea plants and legumious bacteria by near-UV radiation. J Photochem Photobiol B Biol 50:33–37

    CAS  Google Scholar 

  • Shirley BW (1996) Flavonoid biosynthesis: ‘new’ functions for an ‘old’ pathway. Trends Plant Sci 1:377–382

    Google Scholar 

  • Simmonds MSJ (2003) Flavonoid–insect interactions: recent advances in our knowledge. Phytochemistry 64:21–30

    CAS  Google Scholar 

  • Skadhauge B, Thomsen K, von Wettstein D (1997) The role of barley testa layer and its flavonoid content in resistance to Fusarium infections. Hereditas 126:147–160

    CAS  Google Scholar 

  • Snyder BA, Leite B, Hipskind J, Butler LG, Nicholson RL (1991) Accumulation of sorghum phytoalexins induced by Colletotrichum graminicola at the infection site. Physiol Mol Plant Pathol 39:463–470

    CAS  Google Scholar 

  • Snyder BA, Nicholson RL (1990) Synthesis of phytoalexins in sorghum as a site specific response to fungal ingress. Science 248:1637–1639

    CAS  Google Scholar 

  • Sosa T, Chaves N, Alias JC, Escudero JC, Henao F, Gutiérrez-Merino C (2004) Inhibition of mouth skeletal muscle relaxation by flavonoids of Cistus ladanifer L.: a plant defense mechanism against herbivores. J Chem Ecol 30:1087–1101

    CAS  Google Scholar 

  • Stewart AJ, Chapman W, Jenkins GI, Graham I, Martin T, Crozier A (2001) The effect of nitrogen and phosphorus deficiency on flavonol accumulation in plant tissues. Plant Cell Environ 24:1189–1197

    CAS  Google Scholar 

  • Tattini M, Galardi C, Pinelli P, Massai R, Remorini D, Agati G (2004) Differential acumulation of flavonoids and hydroxycinnamates in leaves of Ligustrum vulgare under excess light and drought stress. New Phytol 163:547–561

    CAS  Google Scholar 

  • Tegelberg R, Julkunen-Tiitto R, Aphalo PJ (2004) Red:far-red light ratio and UV-B radiation: their effects on leaf phenolics and growth of silver birch seedlings. Plant Cell Environ 27:1005–1013

    CAS  Google Scholar 

  • Teklemariam T, Blake TJ (2003) Effects of UVB preconditioning on heat tolerance of cucumber (Cucumis sativus L.). Environ Exp Bot 50:169–182

    CAS  Google Scholar 

  • Thoison O, Sévenet T, Niemeyer HM, Russell GB (2004) Insect antifeedant compounds from Nothofagus dombeyi and N. pumilio. Phytochemistry 65:2173–2176

    CAS  Google Scholar 

  • Tomita-Yokotani K, Kato T, Parvez MM, Mori Y, Goto N, Hasegawa K (2003) Approach of allelopathy study with Arabidopsis thaliana (L.) Hevnh. and Neurospora crassa. Weed Biol Manag 3:93–97

    Google Scholar 

  • Treutter D, Feucht W (1990) The pattern of flavan-3-ols in relation to scab resistance of apple cultivars. J Hort Sci 65:511–517

    CAS  Google Scholar 

  • VanLoon JJA, Wang CZ, Nielsen JK, Gols R, Qiu YT (2002) Flavonoids from cabbage are feeding stimulants for diomandback moth larvae additional to glucosinolates: chemoreception and behaviour. Entomol Exp Appl 104:27–34

    CAS  Google Scholar 

  • Venisse J-S, Malnoy M, Faize M, Paulin J-P, Brisset M-N (2002) Modulation of defense responses of Malus ssp. during compatible and incompatible interactions with Erwinia amylovora. MPMI 15:1204–1212

    CAS  Google Scholar 

  • Webster G, Jain V, Davey MR, Gough C, Vasse J, Dénarié J, Coking EC (1998) The flavonoid naringenin stimulates the intercellular colonization of wheat roots by Azorhizobium caulinodans. Plant Cell Environ 21:373–383

    CAS  Google Scholar 

  • Widstrom NW, Snook ME (2001) Recurrent selection for maysin, a compound in maze silks, antibiotic to earworm. Plant Breed 120:357–359

    CAS  Google Scholar 

  • Winkel-Shirley B (1999) Evidence for enzyme complexes in the phenylpropanoid and flavonoid pathways. Physiol Plant 107:142–149

    CAS  Google Scholar 

  • Yamamoto M, Nakatsuka S, Otani H, Kohmoto K, Nishimura S (2000) (+)-Catechin acts as an infection-inhibiting factor in strawberry leaf. Phytopathology 90:595–600

    CAS  Google Scholar 

  • Yilmaz Y, Toledo RT (2004) Health aspects of functional grape seed constituents. Trends Food Sci Technol 15422–33

  • Zhang D, Quantick PC (1997) Effects of chitosan coating on enzymatic browning and decay during postharvest storage of litchi (Litchi chinensis Sonn.) fruit. Postharvest Biol Technol 12:195–202

    CAS  Google Scholar 

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Correspondence to Dieter Treutter.

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Selected articles from the XXII International Conference on Polyphenols, Helsinki, Finland, organized by Prof. Kristiina Wähälä.

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Treutter, D. Significance of flavonoids in plant resistance: a review. Environ Chem Lett 4, 147–157 (2006). https://doi.org/10.1007/s10311-006-0068-8

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