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Interaktion zwischen schlafbezogenen Atemstörungen und Epilepsie

Interaction between sleep-related respiratory disorders and epilepsy

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Zusammenfassung

Schlafbezogene Atemstörungen sind eine Krankheitsentität mit unterschiedlichen Ursachen, die eine hohe Prävalenz hat. Sie ist Grundlage einer Vielzahl von chronischen Komorbiditäten und kann akut die physische und psychische Tagesbefindlichkeit der Betroffenen deutlich beeinträchtigen. Im Vordergrund stehen die Symptome des nichterholsamen Schlafes mit Tagesmüdigkeit/-schläfrigkeit, Aufmerksamkeits- und Merkfähigkeitsstörungen sowie psychische Symptome z. B. der Depression. All diese Symptome können gleichermaßen Ausdruck einer Epilepsie sein, sei es strukturell oder funktionell, durch wiederkehrende, z. B. nächtliche Anfälle oder als Störwirkung in der medikamentösen und/oder neurostimulativen Behandlung. Für eine individuelle, symptomorientierte und erfolgreiche Therapie ist es entsprechend notwendig, die Interaktionen der Krankheiten zu kennen und sie im klinischen „follow up“ zu differenzieren.

Abstract

Sleep-related breathing disorder is an umbrella term for a disease entity with a variety of causes, which has a high prevalence. It is the basis for a multitude of chronic comorbidities and which can significantly impair the daily physical and mental well-being of those affected. The main symptoms are those of non-restorative sleep with daytime sleepiness and fatigue, attention and awareness disorders as well as mental symptoms, such as depression. All these symptoms can also represent an expression of epilepsy, be it structural or functional, due to recurrent nocturnal seizures or as an interference effect in the drug and/or neurostimulative treatment. For an individual symptom-oriented and successful therapy it is therefore necessary to recognize the interaction of the diseases and to differentiate them in the clinical follow-up.

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Lanz, M. Interaktion zwischen schlafbezogenen Atemstörungen und Epilepsie. Z. Epileptol. 32, 47–51 (2019). https://doi.org/10.1007/s10309-018-0228-4

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