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Magnetic source imaging

Indications for MSI in the presurgical evaluation of patients with refractory epilepsy

Quellenlokalisation

Indikationen für die Magnetenzephalographie in der präoperativen Untersuchung von Patienten mit refraktorischer Epilepsie

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Abstract

The advantages of magnetoencephalography (MEG) in the field of epilepsy are numerous; just like electroencephalography (EEG), MEG is able to noninvasively measure epilepsy-specific information (i. e., the brain activity) independent of blood flow with a very high temporal resolution in the order of milliseconds. Thanks to its unique sensitivity to tangential sources, it gives the full picture when combined with EEG. It allows for accurate source imaging and shows a high sensitivity for neocortical sources. In this article, the technique and its clinical impact are reviewed.

Zusammenfassung

Die Magnetenzephalographie (MEG) bietet für die Anwendung in der Epileptologie verschiedene Vorteile. Ähnlich wie die Elektroenzephalographie (EEG) kann die MEG epilepsieassoziierte Muster der Hirnaktivität nichtinvasiv messen, unabhängig vom Blutfluss und mit einer sehr hohen zeitlichen Auflösung im Bereich von Millisekunden. Aufgrund der einzigartigen Sensitivität für tangentiale Quellen liefert sie in Kombination mit der EEG ein umfassendes Bild. Sie ermöglicht eine genaue Quellenanalyse und verfügt dabei über eine hohe Sensitivität für neokortikale Quellen. Der vorliegende Artikel beschreibt das Verfahren und fasst den Einfluss auf die klinische Praxis zusammen.

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Authors and Affiliations

  1. Reference Center for Refractory Epilepsy, Neurology Department, Ghent University Hospital, C. Heymanlaan 10, 9000, Gent, Belgium

    Evelien Carrette PhD

  2. Departement of Neurology-Biomagnetism, University Hospital Erlangen, Erlangen, Germany

    Hermann Stefan

Authors
  1. Evelien Carrette PhD
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  2. Hermann Stefan
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Correspondence to Evelien Carrette PhD.

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Conflict of interest

Dr. Carrette has received refunding for travel and registration costs and Prof. Stefan has received honoraria and travel reimbursement for lectures.

This article does not contain any studies with human participants or animals performed by any of the authors.

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Carrette, E., Stefan, H. Magnetic source imaging. Z. Epileptol. 31, 192–196 (2018). https://doi.org/10.1007/s10309-018-0186-x

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  • DOI: https://doi.org/10.1007/s10309-018-0186-x

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