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Erfolgreiche Epilepsiechirurgie bei seit über 20 Jahren therapierefraktärer Temporallappenepilepsie und multiplen Voreingriffen

Successful surgical therapy in the a case of temporal lobe epilepsy with more than 20 years of drug resistance and several previous surgeries

  • Der epilepsiechirurgische Fall
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Zusammenfassung

Epilepsie ist eine der häufigsten chronischen neurologischen Erkrankungen und stellt für die Betroffenen und Angehörigen eine erhebliche Belastung dar. Wir berichten über einen Patienten, bei dem trotz über 20 Jahren dauernden therapierefraktärem Verlauf und multiplen Voreingriffen eine langjährige Anfallsfreiheit durch einen epilepsiechirurgischen Eingriff erreicht werden konnte. Der Fallbericht verdeutlicht, dass bei therapierefraktärem Verlauf einer Epilepsie eine zeitnahe prächirurgische Evaluation erfolgen sollte, um den Verlauf der Erkrankung positiv zu beeinflussen und soziale Folgen abzumildern.

Abstract

Epilepsy is a common chronic neurological disease and represents a significant burden for patients and their families. We present a case of a patient, who had a pharmacoresistant epilepsy for more than 20 years and several previous surgeries. He achieved long lasting seizure freedom after an epilepsy surgery. The case illustrates that pharmacoresistant epilepsy should prompt presurgical evaluation in order to influence the course of the illness and to attenuate social consequences.

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Authors and Affiliations

  1. Klinik für Neurologie und Epilepsiezentrum Hessen, Philipps-Universität Marburg, Marburg, Deutschland

    Hannah Brazel, Philipp S. Reif, Sebastian Bauer, Anke Hermsen, Susanne Knake, Felix Rosenow &  Adam Strzelczyk

  2. Epilepsiezentrum Frankfurt Rhein-Main, Klinik für Neurologie, J.W. Goethe Universität, Schleusenweg 2–16, Haus 95, 60528, Frankfurt am Main, Deutschland

    Philipp S. Reif, Sebastian Bauer, Anke Hermsen, Felix Rosenow &  Adam Strzelczyk

  3. Institut für Neuropathologie, Philipps-Universität Marburg, Marburg, Deutschland

    Axel Pagenstecher

  4. Institut für Pathologie, Bereich Neuropathologie, Ruhr-Universität Bochum, Bochum, Deutschland

    Volkmar H. Hans

  5. Klinik für Neurochirurgie, Universitätsklinikum Essen, Essen, Deutschland

    Ulrich Sure

Authors
  1. Hannah Brazel
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  2. Philipp S. Reif
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  3. Sebastian Bauer
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  4. Anke Hermsen
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  5. Axel Pagenstecher
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  6. Volkmar H. Hans
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  7. Ulrich Sure
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  8. Susanne Knake
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  9. Felix Rosenow
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  10. Adam Strzelczyk
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Corresponding author

Correspondence to Adam Strzelczyk.

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Interessenkonflikt

H. Brazel, P.S. Reif, S. Bauer, A. Hermsen, A. Pagenstecher, V.H. Hans, U. Sure, S. Knake, F. Rosenow und A. Strzelczyk geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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Brazel, H., Reif, P.S., Bauer, S. et al. Erfolgreiche Epilepsiechirurgie bei seit über 20 Jahren therapierefraktärer Temporallappenepilepsie und multiplen Voreingriffen. Z. Epileptol. 29, 156–160 (2016). https://doi.org/10.1007/s10309-016-0044-7

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  • DOI: https://doi.org/10.1007/s10309-016-0044-7

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