Skip to main content
Log in

Versorgungsmedizinische Aspekte der Epilepsien des höheren Lebensalters

Healthcare medical aspects of epilepsy in old age

  • Leitthema
  • Published:
Zeitschrift für Epileptologie Aims and scope Submit manuscript

Zusammenfassung

Epilepsie ist eine der häufigsten chronisch-neurologischen Erkrankungen, deren Prävalenz mit dem Alter zunimmt. Eine erschwerte Diagnosestellung in späten Lebensjahren aufgrund einer veränderten, blanden Semiologie und Komorbiditäten führt wahrscheinlich zur regelhaften Unterdiagnostizierung in dieser Altersgruppe. Die Wahrscheinlichkeit für das Auftreten von anfallsbedingten Verletzungen und Unfällen nimmt mit dem Patientenalter zu. Risikofaktoren sind häufige Anfälle mit Stürzen und Bewusstseinsverlust. Viele ältere Patienten mit Epilepsie werden durch den Hausarzt betreut und mit älteren Antikonvulsiva behandelt. Daher sind die direkten Krankheitskosten im ambulanten Bereich häufig geringer als bei jüngeren Patienten. Die sozialen Folgen der Altersepilepsie können erheblich sein und eine starke Einschränkung der Mobilität bis zur Aufgabe eines selbstständigen Wohnens zur Folge haben.

Abstract

Epilepsy is one of the most frequent chronic diseases of the central nervous system. Although its prevalence increases with age the diagnosis in later life is made difficult by an altered semiology and comorbidities that probably result in a constant underdiagnosis among elderly individuals. The likelihood of seizure-related injuries and accidents increases with age. Risk factors include frequent seizures with falls and loss of consciousness. Many elderly epilepsy patients are seen by family physicians and treated with older anticonvulsants; therefore, direct costs of illness tend to be lower compared to younger patients. The social consequences of epilepsy in the elderly can be substantial, may lead to severe restrictions of mobility and can result in loss of self-sufficient living.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abbreviations

SE:

Status epilepticus

SUDEP:

„sudden unexpected death in epilepsy“ (plötzlicher unerwarteter Tod bei Epilepsie)

TLE:

Temporallappenepilepsie

Literatur

  1. Hamer HM et al (2012) Prevalence, utilization, and costs of antiepileptic drugs for epilepsy in Germany – a nationwide population-based study in children and adults. J Neurol 259(11):2376–2384

    Article  PubMed  Google Scholar 

  2. Forsgren L et al (2005) The epidemiology of epilepsy in Europe – a systematic review. Eur J Neurol 12(4):245–253

    Article  CAS  PubMed  Google Scholar 

  3. Gustavsson A et al (2011) Cost of disorders of the brain in Europe 2010. Eur Neuropsychopharmacol 21(10):718–779

    Article  CAS  PubMed  Google Scholar 

  4. Olafsson E et al (2005) Incidence of unprovoked seizures and epilepsy in Iceland and assessment of the epilepsy syndrome classification: a prospective study. Lancet Neurol 4(10):627–634

    Article  PubMed  Google Scholar 

  5. Godfrey JB (1989) Misleading presentation of epilepsy in elderly people. Age Ageing 18(1):17–20

    Article  CAS  PubMed  Google Scholar 

  6. Ramsay RE, Macias FM, Rowan AJ (2007) Diagnosing epilepsy in the elderly. Int Rev Neurobiol 81:129–151

    Article  PubMed  Google Scholar 

  7. Ramsay RE, Rowan AJ, Pryor FM (2004) Special considerations in treating the elderly patient with epilepsy. Neurology 62(5 Suppl 2):S24–S29

    Article  PubMed  Google Scholar 

  8. Lüders H et al (1998) Semiological seizure classification. Epilepsia 39(9):1006–1013

    Article  PubMed  Google Scholar 

  9. Stefan H (2011) Epilepsy in the elderly: facts and challenges. Acta Neurol Scand 124(4):223–237

    Article  CAS  PubMed  Google Scholar 

  10. Destatis SB (2012) Alleinlebende in Deutschland – Ergebnisse des Mikrozensus 2011. In: Destatis SB (Hrsg) Statistisches Bundesamt, Wiesbaden, S 16–17. https://www.destatis.de

  11. Pugh MJ et al (2005) The impact of epilepsy on health status among younger and older adults. Epilepsia 46(11):1820–1827

    Article  PubMed  Google Scholar 

  12. Brodie MJ, Elder AT, Kwan P (2009) Epilepsy in later life. Lancet Neurol 8(11):1019–1030

    Article  PubMed  Google Scholar 

  13. Leach JP et al (2005) Epilepsy in the UK: misdiagnosis, mistreatment, and undertreatment? The Wrexham area epilepsy project. Seizure 14(7):514–520

    Article  CAS  PubMed  Google Scholar 

  14. Hamer HM et al (2006) Direct and indirect costs of refractory epilepsy in a tertiary epilepsy center in Germany. Epilepsia 47(12):2165–2172

    Article  PubMed  Google Scholar 

  15. Strzelczyk A et al (2012) Evaluation of health-care utilization among adult patients with epilepsy in Germany. Epilepsy Behav 23(4):451–457

    Article  PubMed  Google Scholar 

  16. Reuber M, Torane P, Mack C (2010) Do older adults have equitable access to specialist epilepsy services? Epilepsia 51(11):2341–2343

    Article  PubMed  Google Scholar 

  17. Bagshaw J, Crawford P, Chappell B (2009) Care in people 60 years of age and over with chronic or recently diagnosed epilepsy: a note review in United Kingdom general practice. Seizure 18(1):57–60

    Article  PubMed  Google Scholar 

  18. Luhdorf K, Jensen LK, Plesner AM (1986) Epilepsy in the elderly: incidence, social function, and disability. Epilepsia 27(2):135–141

    Article  CAS  PubMed  Google Scholar 

  19. Strzelczyk A et al (2014) Epilepsiebedingte Verletzungen und Unfälle. Risikofaktoren und Häufigkeit. Nervenheilkunde 33(5):331–334

    Google Scholar 

  20. Lawn ND et al (2004) Injuries due to seizures in persons with epilepsy: a population-based study. Neurology 63(9):1565–1570

    Article  CAS  PubMed  Google Scholar 

  21. Friedman DE, Gilliam FG (2010) Seizure-related injuries are underreported in pharmacoresistant localization-related epilepsy. Epilepsia 51(1):43–47

    Article  PubMed  Google Scholar 

  22. Forsgren L et al (2005) Mortality of epilepsy in developed countries: a review. Epilepsia 46(Suppl 11):18–27

    Article  PubMed  Google Scholar 

  23. Lhatoo SD et al (2001) Mortality in epilepsy in the first 11 to 14 years after diagnosis: multivariate analysis of a long-term, prospective, population-based cohort. Ann Neurol  49(3):336–344

    Article  CAS  PubMed  Google Scholar 

  24. Neligan A et al (2011) The long-term risk of premature mortality in people with epilepsy. Brain 134(Pt 2):388–395

    Article  PubMed  Google Scholar 

  25. Knake S et al (2001) Incidence of status epilepticus in adults in Germany: a prospective, population-based study. Epilepsia 42(6):714–718

    Article  CAS  PubMed  Google Scholar 

  26. Rosenow F, Hamer HM, Knake S (2007) The epidemiology of convulsive and nonconvulsive status epilepticus. Epilepsia 48(Suppl 8):82–84

    Article  PubMed  Google Scholar 

  27. Waterhouse EJ et al (1998) Synergistic effect of status epilepticus and ischemic brain injury on mortality. Epilepsy Res 29(3):175–183

    Article  CAS  PubMed  Google Scholar 

  28. Strzelczyk A et al (2008) Cost of epilepsy: a systematic review. Pharmacoeconomics 26(6):463–476

    Article  PubMed  Google Scholar 

  29. Hamer HM et al (2006) Direct and indirect costs of refractory epilepsy in a tertiary epilepsy center in Germany. Epilepsia 47(12):2165–2172

    Article  PubMed  Google Scholar 

  30. Strzelczyk A et al (2013) Trends in resource utilization and prescription of anticonvulsants for patients with active epilepsy in Germany. Epilepsy Behav 27(3):433–438

    Article  PubMed  Google Scholar 

  31. De Zelicourt M et al (2000) The contributing factors to medical cost of epilepsy: an estimation based on a French prospective cohort study of patients with newly diagnosed epileptic seizures (the CAROLE study). Active Coordination of the Longitudinal Observational Network in Epilepsy. Seizure 9(2):88–95

    Article  Google Scholar 

Download references

Einhaltung ethischer Richtlinien

Interessenkonflikt. H.M. Hamer: Redner- und/oder Beratungshonorare von Cerbomed, Eisai, Cyberonics, Desitin, GSK, Neuro-Consil, Pfizer, Thieme, Novartis, UCB. J.D. Lang gibt an, dass kein Interessenkonflikt besteht. Dieser Beitrag enthält keine Studien an Menschen oder Tieren.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to H.M. Hamer.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lang, J., Hamer, H. Versorgungsmedizinische Aspekte der Epilepsien des höheren Lebensalters. Z. Epileptol. 27, 272–275 (2014). https://doi.org/10.1007/s10309-014-0400-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10309-014-0400-4

Schlüsselwörter

Keywords

Navigation