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Infertilität bei Endometriose und Adenomyose – welche Bedeutung hat die Implantation?

Infertility in endometriosis and adenomyosis—What is the importance of the implantation?

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Gynäkologische Endokrinologie Aims and scope

Zusammenfassung

Endometriose ist eine der häufigsten gynäkologischen Erkrankungen. Sie ist per se mit dem Risiko der Subfertilität behaftet. Chronisch-entzündliche Reaktionen und ein verändertes peritoneales Milieu beeinträchtigen die Ovarien und die Eizellqualität. Aborte und Implantationsstörungen kommen häufiger vor. Ob die gestörte Implantation eine größere Rolle spielt als bisher angenommen, ist eine noch nicht hinreichend beantwortete Frage.

Abstract

Endometriosis is one of the most frequent gynecological diseases. It is associated per se with the risk of subfertility. Chronic inflammatory reactions and an altered peritoneal environment impair the ovaries and the quality of oocytes. Miscarriages and implantation disorders are frequent. Whether the impaired implantation plays a more important role than previously assumed is still an insufficiently answered question.

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Authors and Affiliations

  1. Zentrum für Endometriose, Endokrinologie und Reproduktionsmedizin, IVF Baden-Baden, Beethovenstr. 2, 76530, Baden-Baden, Deutschland

    Wolfgang Küpker

  2. Institut für Medizinische Genetik, Universitätsmedizin Rostock, Rostock, Deutschland

    Jörn Bullerdiek

  3. Zentrum für gynäkologische Endokrinologie und Fortpflanzungsmedizin KinderWunschKempten (KWK), Klinik für Frauenheilkunde und Geburtshilfe Klinikum Kempten & Klinik Immenstadt, Klinikverbund Allgäu, Kempten, Deutschland

    Ricardo E. Felberbaum

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  1. Wolfgang Küpker
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  2. Jörn Bullerdiek
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  3. Ricardo E. Felberbaum
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Correspondence to Wolfgang Küpker.

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Interessenkonflikt

W. Küpker, J. Bullerdiek und R.E. Felberbaum geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autor/-innen keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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Georg Griesinger, Lübeck

Wolfgang Küpker, Baden-Baden

Hinweis des Verlags

Der Verlag bleibt in Hinblick auf geografische Zuordnungen und Gebietsbezeichnungen in veröffentlichten Karten und Institutsadressen neutral.

Anteile dieses Artikels wurden publiziert in Küpker W et al. (2024) Endometriose und Infertilität. Gynäkologie 57:131–137. https://doi.org/10.1007/s00129-024-05203-3.

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Küpker, W., Bullerdiek, J. & Felberbaum, R.E. Infertilität bei Endometriose und Adenomyose – welche Bedeutung hat die Implantation?. Gynäkologische Endokrinologie 22, 118–124 (2024). https://doi.org/10.1007/s10304-024-00567-0

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