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Hormonersatztherapie nach Mammakarzinom

Hormone replacement therapy after breast cancer

  • Arzneimitteltherapie
  • Published:
Gynäkologische Endokrinologie Aims and scope

Zusammenfassung

Patientinnen mit Brustkrebs leiden häufig während und nach der Therapie ihrer Erkrankung unter Symptomen, die auf niedrige Östrogenspiegel zurückzuführen sind. Dies kann zur relevanten Beeinträchtigung der Lebensqualität führen. Östrogene können die Symptome zwar lindern, sind aber in dieser Situation grundsätzlich kontraindiziert. Die meisten therapeutischen Alternativen reichen allerdings häufig für eine Symptomkontrolle nicht aus. In Ausnahmefällen kann bei besonders starker Beeinträchtigung der Lebensqualität eine Therapie mit Östrogenen erwogen werden. In dieser Übersicht werden die möglichen Risiken und Behandlungsstrategien erläutert.

Abstract

During and after treatment of the disease, female patients with breast cancer often suffer from symptoms that are due to low estrogen levels. These can lead to a relevant impairment of the quality of life. Estrogens can relieve the symptoms; however, in this situation they are fundamentally contraindicated. Most therapeutic alternatives are, however, often insufficient for symptom control. In exceptional cases treatment with estrogens can be considered in patients with particularly severe impairments of the quality of life. This review article describes the possible risks and treatment strategies.

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Authors and Affiliations

  1. Klinik für Frauenheilkunde und Geburtshilfe, Lehrstuhl der Universität Regensburg, Caritas-Krankenhaus St. Josef, Landshuter Straße 65, 93053, Regensburg, Deutschland

    O. Ortmann

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  1. O. Ortmann
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Correspondence to O. Ortmann.

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Interessenkonflikt

O. Ortmann gibt an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden vom Autor keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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B. Imthurn, Zürich

A.O. Mueck, Tübingen

O. Ortmann, Regensburg

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Ortmann, O. Hormonersatztherapie nach Mammakarzinom. Gynäkologische Endokrinologie 17, 172–174 (2019). https://doi.org/10.1007/s10304-019-0256-9

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  • DOI: https://doi.org/10.1007/s10304-019-0256-9

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