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Nahrungsergänzungsmittel im Klimakterium

Dietary supplements during menopause

  • Leitthema
  • Published:
Gynäkologische Endokrinologie Aims and scope

Zusammenfassung

Das Angebot und die Anwendung von Nahrungsergänzungsmitteln zur Behandlung klimakterischer Beschwerden nehmen in den letzten Jahren kontinuierlich zu. Der Beitrag fasst den aktuellen Wissensstand zur Wirksamkeit von Nahrungsergänzungsmitteln auf Wechseljahresbeschwerden zusammen. Für die Mehrheit der Nahrungsergänzungsmittel ist keine Reduktion von z. B. Hitzewallungen durch Studien nachgewiesen. Nahrungsergänzungsmittel stellen keine Alternative zur kausalen Hormonersatztherapie dar.

Abstract

Dietary supplements are becoming increasingly popular among women seeking alternatives to treatment with estrogens for managing menopausal symptoms. The objective of this paper was to assess the effectiveness of dietary supplements. Although individual trials suggest benefits from certain supplements, data are insufficient to support the effectiveness of dietary supplements for the management of menopausal symptoms.

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Literatur

  1. Antoine C, Liebens F, Carly B et al. (2007) Safety of alternative treatments for menopausal symptoms after breast cancer: a qualitative systematic review. Climacteric 10: 23–26

    Article  PubMed  CAS  Google Scholar 

  2. BfR: http://www.bfr.bund.de

  3. BfArM: http://www.bfarm.de/cln_030/nn_1160684/SharedDocs/Publikationen/DE/Pharmakovigilanz/stufenplverf/kava__bescheid__071221,templateId=raw,property=publicationFile.pdf/kava_bescheid_071221.pdf

  4. Cassidy A, Albertazzi P, Nielsen I et al (2006) Critical review of health effects of soyabean phyto-oestrogens in post-menopausal women. Proc Nutr Soc 65: 76–92

    Article  PubMed  CAS  Google Scholar 

  5. Cheema D, Coomarasamy A, El-Toukhy T (2007) Non-hormonal therapy of post-menopausal vasomotor symptoms: a structured evidence-based review. Arch Gynecol Obstetrics 276: 463–469

    Article  CAS  Google Scholar 

  6. Cheng G, Wilczek B, Warner M et al (2007) Isoflavone treatment for acute menopausal symptoms. Menopause 14: 468–473

    Article  PubMed  Google Scholar 

  7. Foth D, Nawroth F, Mallmann P (2006) Isoflavone und das Endometrium. Geburtsh Frauenheilkd 66: 553–558

    Article  CAS  Google Scholar 

  8. Geller SE, Studee L (2005) Botanical and dietary supplements for menopausal symptoms: what works, what does not. J Womens Healt 14(7): 634–649

    Article  Google Scholar 

  9. Huntley AL, Ernst E (2004) Soy for the treatment of perimenopausal symptoms – a systematic review. Maturitas 47: 1–9

    Article  PubMed  Google Scholar 

  10. Huntley AL, Ernst E (2003) A systemic review of herbal medicinal products for the treatment of menopausal symptoms. Menopause 10: 465–476

    Article  PubMed  Google Scholar 

  11. Krebs EE, Ensrud KE, MacDonald R, Wilt TJ (2004) Phytoestrogens for treatment of menopausal symptoms: a systematic review. Obstet Gynecol 104(4): 824–836

    PubMed  CAS  Google Scholar 

  12. Kronenberg F, Fugh-Berman A (2002) Complementary and alternative medicine for menopausal symptoms: a review of randomised, controlled trials. Ann Int Med 137: 805–813

    PubMed  Google Scholar 

  13. Mahady GB, Parrot J, Lee C et al. (2003) Botanical dietary supplement use in peri- and postmenopausal women. Menopause 10: 65–72

    PubMed  Google Scholar 

  14. Messina M, Ho S, Alekel DL (2004) Skeletal benefits of soy isoflavones: a review of the clinical trial and epidemiological data. Curr Opin Clin Nutr Metab Care 7: 649–658

    Article  PubMed  CAS  Google Scholar 

  15. Messina M, McCaskill-Stevens W, Lampe JW (2006) Addressing the soy and breast relationship: review, commentary, and workshop proceedings. J Natl Cancer Inst 98: 1275–1284

    PubMed  Google Scholar 

  16. NAMS (2000) The role of isoflavones in menopausal health: consensus opinion of The North American Menopause Society. Menopause 7: 215–229

    Article  Google Scholar 

  17. NAMS (2004) Treatment of menopause-associated vasomotor symptoms: position statement of The North American Menopause Society. Menopause 11: 11–33

    Article  Google Scholar 

  18. Nedrow A, Miller J, Walker M et al. (2006) Complementary and alternative therapies for the management of menopause-related symptoms: a systematic evidence review. Arch Intern Med 166(14): 1453–1465

    Article  PubMed  Google Scholar 

  19. Nelson HD. Vesco KK, Haney E et al. (2006) Nonhormonal therapies for menopausal hot flashes. Systematic review and meta-analysis. JAMA 295: 2057–2071

    Article  PubMed  CAS  Google Scholar 

  20. Newton KM, Reed SD, LaCroix AZ et al. (2006) Treatment of vasomotor symptoms of menopause with nlack cohosh, multibotanicals, soy, hormone therapy, or placebo. Ann Intern Med 145: 869–879

    PubMed  Google Scholar 

  21. Palacios S, Pornel B, Bergeron C et al. (2007) Endometrial safety assessment of a specific and standardized soy extract according to international guidelines. Menopause 14(6): 1006–1011

    PubMed  Google Scholar 

  22. Piazza C, Privitera MG, Melilli B et al. (2007) Influence of inulin on plasma isoflavone concentrations in healthy postmenopausal women. AmJ Clin Nutrition 86: 775–780

    CAS  Google Scholar 

  23. Pines A, Sturdee DW, Birkhauser MH et al. (2007) IMS update recommendations on postmenopausal hormone therapy. Climacteric 10: 181–194

    Article  PubMed  CAS  Google Scholar 

  24. Rice S, Whitehead SA (2006) Phytoestrogens and breast cancer – promoters or protectors? Endocrine Related Cancer 13: 995–1015

    Article  PubMed  CAS  Google Scholar 

  25. Tempfer CB, Bentz EK, Leodolter S et al. (2007) Phytoestrogens in clinical practice: a review of the literature. Fertil Steril 87(6): 1243–1249

    Article  PubMed  CAS  Google Scholar 

  26. Trock BJ, Hilakivi-Clarke L, Clarke R (2006) Meta-analysis of soy intake and breast cancer risk. J Natl Cancer Inst 98: 459–471

    Article  PubMed  CAS  Google Scholar 

  27. Ziaei S, Kazemnejad A, Zareai M (2007) The effect of vitamin E on hot flashes in menopausal women. Gynecol Obstet Investigation 64(4): 204–207

    Article  CAS  Google Scholar 

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Interessenkonflikt

Der korrespondierende Autor weist auf folgende Beziehung/en hin: Vortragshonorare von bzw. Beratungstätigkeit für folgende Firmen: Ferring, cmi, Jenapharm, Hexal, Schering, Akzo Nobel, Sono Promedico, qualimedic.

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  1. Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe der Universität zu Köln, Kerpener Straße 34, 50931, Köln, Deutschland

    D. Foth

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  1. D. Foth
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Correspondence to D. Foth.

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Foth, D. Nahrungsergänzungsmittel im Klimakterium. Gynäkologische Endokrinologie 6, 76–81 (2008). https://doi.org/10.1007/s10304-008-0259-4

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  • DOI: https://doi.org/10.1007/s10304-008-0259-4

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