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Chromosomale Ursachen habitueller Aborte

Chromosomal findings in recurrent abortions

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Gynäkologische Endokrinologie Aims and scope

Zusammenfassung

Die Ursachen habitueller Aborte sind sehr vielfältig und in unterschiedlichsten Bereichen zu suchen. Einen wichtigen Aspekt stellen die chromosomalen Fehlverteilungen oder die strukturellen Chromosomenveränderungen dar. Im vorliegenden Beitrag werden die chromosomalen Ursachen von Fehlgeburten ausführlich erläutert und diskutiert.

Abstract

The causes of recurrent abortion are multifarious and found in various fields. One of the main aspects are numerical chromosomal aberrations or structural chromosomal abnormalities. In the following text the chromosomal reasons for abortions are described and discussed.

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Literatur

  1. Abdelhadi I, Colls P, Sandalinas M et al. (2003) Preimplantation genetic diagnosis of numerical abnormalities for 13 chromosomes. RBM online 6:226–231

    PubMed  Google Scholar 

  2. Hassold TJ, Pettay D, Freeman SB et al. (1991) Molecular studies of non-disjunction in trisomy 16. J Med Genet 28:159–162

    CAS  PubMed  Google Scholar 

  3. Kuliev A, Cieslak J, Ilkevitch Y, Verlinsky Y (2003) Chromosomal abnormalities in a series of 6733 human oocytes in preimplantation diagnosis for age-related aneuploidies. RBM online 5:54–59

    Google Scholar 

  4. Nybo Andersen AM, Wohlfahrt J, Christens P et al. (2000) Maternal age and fetal loss: population based register linkage study. BMJ 320:1708–1712

    Article  PubMed  Google Scholar 

  5. Pellestor F, Andreo B, Arnal F et al. (2002) Mechanisms of non-disjunction in human female meiosis: the co-existence of two modes of malsegregation evidenced by the karyotyping of 1397 in-vitro unfertilized oocytes. Hum Reprod 17:2134–2145

    Article  PubMed  Google Scholar 

  6. Pellestor F, Andreo B, Arnal F et al. (2003) Maternal aging and chromosomal abnormalities: new data from in vitro unfertilized human oocytes. Hum Genet 112:195–203

    PubMed  Google Scholar 

  7. Shi Q, Martin RH (2000) Aneuploidy in human sperm: a review of the frequency and distribution of aneuploidy, effects of donor age and lifestyle factors. Cytogenet Cell Genet 90:219–226

    Article  CAS  PubMed  Google Scholar 

  8. Zaragoza MV, Jacobs PA, James RS et al. (1994) Nondisjunction of human acrocentric chromosomes: studies of 432 trisomic fetuses and liveborns. Hum Genet 94:411–417

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Institut für Humangenetik, Universitätsklinikum Schleswig-Holstein, Campus Lübeck

    R. Voigt & E. Schwinger

  2. Klinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Schleswig-Holstein, Campus Lübeck

    R. Axt-Fliedner & K. Diedrich

  3. Institut für Humangenetik, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538 , Lübeck

    R. Voigt

Authors
  1. R. Voigt
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  2. R. Axt-Fliedner
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  3. K. Diedrich
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  4. E. Schwinger
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Correspondence to R. Voigt.

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Voigt, R., Axt-Fliedner, R., Diedrich, K. et al. Chromosomale Ursachen habitueller Aborte. Gynäkologische Endokrinologie 3, 40–44 (2005). https://doi.org/10.1007/s10304-004-0093-2

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  • DOI: https://doi.org/10.1007/s10304-004-0093-2

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