Zusammenfassung
Seit Einführung und Verbreitung der assistieren Reproduktion wird die Gesundheit und die psychosoziale Entwicklung der nach In-vitro-Fertilisation (IVF) und intrazytoplasmatischen Spermieninjektion (ICSI) geborenen Kinder kritisch hinterfragt. Die hierzu vorliegenden Daten werden in dieser Arbeit zusammengestellt und diskutiert. Insgesamt deuten die Daten in die Richtung eines sterilitätsassoziierten Risikos. Ein genetisches Hintergrundsrisiko kann bei vielen Kinderwunschpatienten nicht ausgeschlossen werden. Jedoch scheint die Invasivität der Sterilitätstherapie das Risiko in einer Schwangerschaft bzw. bei Geburt des Kindes nicht zu erhöhen bzw. die postnatale Entwicklung der Kinder nicht zu beeinflussen. Die Sterilität an sich scheint aber einen Faktor darzustellen, der ernst genommen werden muss und offenbar zu einem erhöhten Risiko für Schwangerschaft und Geburt nach IVF bzw. ICSI führt.
Abstract
Since the introduction of assisted reproduction, the health of children born after in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) has been discussed. Data on the physical and mental health of children born after IVF or ICSI are summarized and discussed in this article. According to these data there seems to be a risk attributed to infertility. An unknown genetic risk of the parents often cannot be excluded. The invasive techniques of assisted reproduction themselves do not seem to cause a risk for the child, while infertility seems to be a factor leading to an increased risk for pregnancy and birth after IVF and ICSI.
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Schröder, A.K., Diedrich, K. & Ludwig, M. Wie geht es den Kindern nach assistierter Reproduktion?. Gynäkologische Endokrinologie 1, 170–175 (2003). https://doi.org/10.1007/s10304-003-0040-7
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DOI: https://doi.org/10.1007/s10304-003-0040-7