Skip to main content
Log in

Gattilier

Vitex agnus-castus (Lamiaceae)

  • Matière Médicale
  • Published:
Phytothérapie

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Références

  1. The plantlist: http://www.theplantlist.org/tpl/record/kew-213297

  2. ITIS (Integrated Taxonomic Information System): http://www.itis.gov/servlet/SingleRpt/SingleRpt?search_topic=TSN&search_ value=32221

  3. Tela botanica: http://www.tela-botanica.org/bdtfx-nn-72745-synthese

  4. Meier B (1999) Probleme des Standardisierung phramazeutischer Zubereitungen. Z Phytother 20:145

    Google Scholar 

  5. Wichtl M, Anton R (2003) Plantes thérapeutiques, tradition, pratique officinale, science et thérapeutique. 2 éd, EMInter/Tec & Doc éditions, Paris

    Google Scholar 

  6. Wikimedia: https://commons.wikimedia.org/wiki/File:Vitexagnus-castus-foliage.JPG

  7. http://www.backyardnature.net/n/14/140316vy.jpg

  8. Kuruüzüm-Uz A, Ströch K, Demirezer LO, et al (2003) Glucosides from Vitex agnus-castus. Phytochemistry 63:959–64

    Article  PubMed  Google Scholar 

  9. Hirobe C, Qiao ZS, Takeya K, et al (1997) Cytotoxic flavonoids from Vitex agnus-castus. Phytochemistry 46:521–4

    Article  CAS  PubMed  Google Scholar 

  10. Hajdú Z, Hohmann J, Forgo P, et al (2007) Diterpenoids and flavonoids from the fruits of Vitex agnus-castus and antioxidant activity of the fruit extracts and their constituents. Phytother Res 21:391–4

    Article  PubMed  Google Scholar 

  11. Aissaoui H, Algabr M, Mezhoud S, et al (2016) Chemical constituents of Vitex agnus-castus (Verbenaceae). Pharma Chemica 8:491–4

    Google Scholar 

  12. Hoberg E, Sticher O, Orjala JE, et al (1999) Diterpene aus Agnicasti fructus und ihre Analytik. Z Phytother 20:140–58

    Google Scholar 

  13. Males Z, Blazević N, Antolić A (1998) The essential oil composition of Vitex agnus-castus f. rosea leaves and flowers. Planta Med 64:286–7

    Article  CAS  PubMed  Google Scholar 

  14. Stojkovic D, Sokovic M, Glamočlija J (2011) Chemical composition and antimicrobial activity of Vitex agnus-castus L. fruits and leaves essential oils. Food Chem 128:1017–22

    Article  CAS  Google Scholar 

  15. Choudhary MI, Azizuddin, Jalil S, et al (2009) Antiinflammatory and Lipoxygenase Inhibitory Compounds from Vitex agnuscastus Phytother Res 23:1336–9

    Article  CAS  PubMed  Google Scholar 

  16. Liu J, Burdette JE, Xu H, et al (2001) Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J Agric Food Chem 49:2472–9

    Article  CAS  PubMed  Google Scholar 

  17. Jarry H, Leonhardt S, Gorkow C, et al (1994) In vitro prolactin but not LH and FSH release is inhibited by compounds in extracts of agnus-castus: direct evidence for a dopaminergic principle by the dopamine receptor assay. Exp Clin Endocrinol 102:448–54

    Article  CAS  PubMed  Google Scholar 

  18. Milewicz A, Gejdel E, Sworen H, et al (1993) Vitex agnus-castus extract in the treatment of luteal phase defects due to latent hyperprolactinaemia. Results of a randomized placebocontrolled double blind study. Arnzneimittelforschung 43:752–6

    CAS  Google Scholar 

  19. Westphal LM, Polan ML, Trant AS, et al (2004) A nutritional supplement for improving fertility in women. A pilot study. J Reprod Med 49:289–93

    CAS  PubMed  Google Scholar 

  20. Arentz S, Abbott JA, Smith CA, et al (2014) Herbal medicine for the management of polycystic ovary syndrome (PCOS) and associated oligo/amenorrhoea and hyperandrogenism; a review of the laboratoryevidence for effects with corroborative clinical findings. BMC Complement Altern Med 14:511

    Article  PubMed  PubMed Central  Google Scholar 

  21. Allahtavakoli M, Honari N, Pourabolli I, et al (2015) Vitex agnus-castus extract improves learning and memory and increases the transcription of estrogen receptor α in hippocampus of ovariectomized rats. Basic Clin Neurosci 6:185–92

    PubMed  PubMed Central  Google Scholar 

  22. Sliutz G, Speiser P, Schultz AM, et al (1993) Agnus-castus extracts inhibit prolactin secretion of rat pituitary cells. Horm Metab Res 25:253–5

    Article  CAS  PubMed  Google Scholar 

  23. Jarry H, Leonhardt S, Spengler B, et al (1999) Auf der suche nach dopaminergen substanzen in agnicasti- fructus-präparaten: warum eigentlich? Z Phytother 20:140–58

    Google Scholar 

  24. Halaška M, Beles P, Gorkow C, et al (1999) Treatment of cyclical mastalgia with a solution containing a Vitex agnus-castus extract: results of a placebo-controlled double-blind study. Breast 8:175

    Article  PubMed  Google Scholar 

  25. Wuttke W, Jarry H, Christoffel V, et al (1997) Behandlung zyklusabhängiger Brustschmerzen mit einem agnus-castus-haltigen Arzneimittel. Geburtshilfe Frauenheilkd 57:1–14

    Article  Google Scholar 

  26. Webster DE, Lu J, Chen SN, et al (2006) Activation of the μ- opiate receptor by Vitex agnus-castus methanol extracts: implication for its use in PMS. J Ethnopharmacol 106:216–21

    Article  CAS  PubMed  Google Scholar 

  27. Brugisser R, Burkhard W, Simmen U, et al (1999) Untersuchungen an opioid-rezeptoren mit Vitex agnus-castus L. Z Phytother 20:140–58

    Google Scholar 

  28. Schellenberg R (2001) Treatment for the premenstrual syndrome with agnus-castus fruit extract: prospective, randomised, placebo controlled study. BMJ 322:134–7

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Atmaca M, Kumru S, Tezcan E, et al (2003) Fluoxetine versus Vitex agnus-castus extract in the treatment of premenstrual dysphoric disorder. Human Psychopharmacol Clin Exp 18:191–5

    Article  CAS  Google Scholar 

  30. Loch EG, Selle H, Boblitz N (2000) Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus-castus. J Womens Health Gend Based Med 9:315–20

    Article  CAS  PubMed  Google Scholar 

  31. Berger D, Schaffner W, Schrader E, et al (2000) Efficacy of Vitex agnus-castus L. extract Ze 440 in patients with premenstrual syndrome (PMS). Arch Gynecol Obstet 264:150–3

    Article  CAS  PubMed  Google Scholar 

  32. Lauritzen CH, Reuter HD, Repges R, et al (1997) Treatment of premenstrual tension syndrome with Vitex agnus-castus controlled, double-blind study versus pyridoxine. Phytomedicine 4:183–9

    Article  CAS  PubMed  Google Scholar 

  33. Dericks-Tan JSE, Schwinn P, Hildt C (2003) Dose-dependent stimulation of melatonin secretion after administration of agnuscastus. Exp Clin Endocrinol Diabetes 111:44–6

    Article  CAS  PubMed  Google Scholar 

  34. Liou CJ, Len WB, Wu SJ, et al (2014) Casticin inhibits COX-2 and iNOS expression via suppression of NF-κB and MAPK signaling in lipopolysaccharide-stimulated mouse macrophages. J Ethnopharmacol 158 pt A:310–6

    Google Scholar 

  35. Eftekhari MH, Rostami ZH, Emami MJ, et al (2014) Effects of “ Vitex agnus-castus” extract and magnesium supplementation, alone and in combination, on osteogenic and angiogenic factors and fracture healing in women with long bone fracture. J Res Med Sci 19:1–7

    PubMed  PubMed Central  Google Scholar 

  36. Merz PG, Gorkow C, Schrödter A, et al (1996) The effects of a special agnus-castus (BP1095E1) on prolactin secretion in healthy male subjects. Exp Clin Endrocrinol Diabetes 104:447–53

    Article  CAS  Google Scholar 

  37. Brattsrtöm A, Kaiser WD (2010) Das Restless-legs-Syndrom (RLS) — Erfahrungsbericht mit einem Vitex agnus-castus (VAC)-Extrakt. Z Phytother 31:247–50

    Article  Google Scholar 

  38. Detienne M (1972) Les jardins d’Adonis, la mythologie des aromates en Grèce. NRF, Gallimard, Paris

    Google Scholar 

  39. Daniele C, Thompson-Coon J, Pittler MH (2005) Vitex agnuscastus: a systematic review of adverse events. Drug Saf 28:319–32

    Article  PubMed  Google Scholar 

Bibliographie institutionnelle

  1. American Herbal Pharmacopoeia, BHP 1996, BP 2007, BHMA 2003, Complete German Commission E 1998, ESCOP 2003, Martindale 35th edition, PhEur 2007, WHO Monographs on Selected Medicinal Plants 2009

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to K. Ghedira.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ghedira, K., Goetz, P. Gattilier. Phytothérapie 14, 264–268 (2016). https://doi.org/10.1007/s10298-016-1061-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10298-016-1061-4

Navigation