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Étude randomisée comparant l’efficacité d’Hericium erinaceus versus huiles essentielles sur Helicobacter pylori (HP)

Randomized study comparing the efficacy of Hericium versus essential oils against Helicobacter pylori (HP) infection

Phytothérapie volume 12, pages 3–5 (2014)Cite this article

Résumé

Une étude prospective randomisée croisée compare l’efficacité du Hericium erinaceus (Hericium) versus huiles essentielles (HE) fixées sur Laetiporus sulfureus contre Helicobacter pylori (HP). Vingt-cinq patient(e)s ont été inclus(e)s. Les patients qui ont reçu Hericium ont répondu favorablement dans 89,5 % des cas alors que ceux traités par (HE) n’ont négativé le test Pyloritop® que dans 33,3 % des cas (p < 0,01). Aucun effet secondaire n’a été déclaré. Le Hericium pourrait être une alternative intéressante à l’antibiothérapie. Une étude randomisée portant sur plus de patients et versus le traitement référentiel permettrait d’améliorer nos connaissances sur des traitements mieux tolérés.

Abstract

A prospective randomized study compared the efficacy of Hericium versus essentials oils fixed on Laetiporus sulfureus against Helicobacter pylori (HP) infection. Twenty-five patients were included. Patients who received Hericium showed negative results for Pyloritop® test in 89.5% of the cases against 33.3% only for patients who started with essential oils. No adverse event was reported. Hericium could be an alternative to antibiotic therapy. Additional randomized study versus referential therapy should be performed to put more focus on treatment devoid of adverse reaction.

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Références

  1. Bergonzelli GE, Donnicola D, Porta N, Corthésy-Theulaz IE (2003) Essential oils as components of a diet-based approach to management of Helicobacter infection. Antimicrob Agents Chemother 10: 3240–6

    Article  Google Scholar 

  2. Dobbs RJ, Dobbs SM, Weller C, et al. (2008) Helicobacter hypothesis for idiopathic parkinsonism: before and beyond. Helicobacter 5: 309–22

    Article  Google Scholar 

  3. Esmaeili D, Mobarez AM, Tohidpour A (2012) Anti-Helicobacter pylori activities of shoya powder and essential oils of thymus vulgaris and eucalyptus globulus. Open Microbiol J 6: 65–9

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  4. Gisbert JP (2005) The recurrence of Helicobacter pylori infection: incidence and variables influencing it. A critical review. Am J Gastroenterol 9: 2083–99

    Article  Google Scholar 

  5. Helicobacter and Cancer Collaborative Group (2001) Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts [archive]. Gut 49: 347–53

    Article  Google Scholar 

  6. Imai H, Osawa K, Yasuda H, et al. (2001) Inhibition by the essential oils of peppermint and spearmint of the growth of pathogenic bacteria. Microbios 106: 31–9

    CAS  PubMed  Google Scholar 

  7. Inoue I, Mukoubayashi C, Yoshimura N, et al. (2011) Elevated risk of colorectal adenoma with Helicobacter pylori-related chronic gastritis: a population-based case-control study. Int J Cancer 11: 2704–11

    Article  Google Scholar 

  8. Jung J, Lee JH, Bae KH, Jeong CS (2011) Anti-gastric actions of eugenol and cinnamic acid isolated from Cinnamomi Ramulus. Yakugaku Zasshi 7: 1103–10

    Article  Google Scholar 

  9. Kamangar F, Sheikhattari P, Mohebtash M (2011) Helicobacter pylori and its effects on human health and disease. Arch Iran Med 3: 192–9

    Google Scholar 

  10. Kodama M, Murakami K, Okimoto T, et al. (2012) Ten-year prospective follow-up of histological changes at five points on the gastric mucosa as recommended by the updated Sydney system after Helicobacter pylori eradication. J Gastroenterol 4: 394–403

    Article  Google Scholar 

  11. Kountouras J, Boziki M, Gavalas E, et al. (2010) Five-year survival after Helicobacter pylori eradication in Alzheimer disease patients. Cogn Behav Neurol 3: 199–204

    Article  Google Scholar 

  12. Lin J, Huang WW (2009) A systematic review of treating Helicobacter pylori infection with Traditional Chinese Medicine. World J Gastroenterol 37: 4715–9

    Article  Google Scholar 

  13. Lin Y, Ueda J, Kikuchi S, et al. (2011) Comparative epidemiology of gastric cancer between Japan and China. World J Gastroenterol 39: 4421–8

    Article  Google Scholar 

  14. Malfertheiner P, Megraud F, O’Morain CA, et al. (2012) Management of Helicobacter pylori infection — the Maastricht IV/Florence Consensus Report. Gut 5: 646–64

    Article  Google Scholar 

  15. Nir Y, Potasman I, Stermer E, et al. (2000) Controlled trial of the effect of cinnamon extract on Helicobacter pylori. Helicobacter 2: 94–7

    Article  Google Scholar 

  16. O’Mahony R, Al-Khtheeri H, Weerasekera D, et al. (2005) Bactericidal and anti-adhesive properties of culinary and medicinal plants against Helicobacter pylori. World J Gastroenterol 47: 7499–507

    Google Scholar 

  17. Qian J, Ye F, Zhang J, et al. (2012) Levofloxacin-containing triple and sequential therapy or standard sequential therapy as the first line treatment for Helicobacter pylori eradication in China. Helicobacter 6: 478–85

    Article  Google Scholar 

  18. Risch HA (2012) Pancreatic cancer: Helicobacter pylori colonization, N-Nitrosamine exposures, and ABO blood group. Mol Carcinog 1: 109–18

    Article  Google Scholar 

  19. Sachs G, Scott DR, Wen Y (2011) Gastric Infection by Helicobacter pylori. Curr Gastroenterol Rep 6: 540–6

    Article  Google Scholar 

  20. Sugizaki K, Sakata Y, Arai T, et al. (2012) A multicenter prospective observational study of triple therapy with rabeprazole, amoxicillin and metronidazole for Helicobacter pylori in Japan. Intern Med 22: 3103–8

    Google Scholar 

  21. Tabak M, Armon R, Potasman I, Neeman I (1996) In vitro inhibition of Helicobacter pylori by extracts of thyme. J Appl Bacteriol 6: 667–72

    Article  Google Scholar 

  22. Tabak M, Armon R, Neeman I (1999) Cinnamon extracts’ inhibitory effect on Helicobacter pylori. J Ethnopharmacol 3: 269–77

    Article  Google Scholar 

  23. Xu CP, Liu WW, Liu FX, et al. (1985) A double-blind study of effectiveness of hericium erinaceus pers therapy on chronic atrophic gastritis. A preliminary report. Chin Med J (Engl) 6: 455–6

    Google Scholar 

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  1. Gastroentérologue hépatologue (DES), cancérologue (DESC), immunologue (DEA/DESC), 40, rue du Docteur-Roux, F-51350, Cormontreuil, France

    B. Donatini

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  1. B. Donatini
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Correspondence to B. Donatini.

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Donatini, B. Étude randomisée comparant l’efficacité d’Hericium erinaceus versus huiles essentielles sur Helicobacter pylori (HP). Phytothérapie 12, 3–5 (2014). https://doi.org/10.1007/s10298-014-0831-5

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  • DOI: https://doi.org/10.1007/s10298-014-0831-5

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