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Le Grifola frondosa (maïtaké) : un régulateur du syndrome métabolique: poids, cholestérol, glycémie et hypertension artérielle; accessoirement un immunostimulant

Grifola frondosa (maïtaké) controles metabolic syndrome: body weight, cholesterol excess, diabetes and hypertension; incidentely a mild TH1 stimulator

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  • Biothérapie — Mycothérapie
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Phytothérapie

Résumé

Le maïtaké — Grifola frondosa (GF) — stimule les voies TH1 et TH2. L’activation de la voie TH1 se traduit par des effets anti-infectieux (listeria, virus de l’herpès ou de la grippe) et antitumoraux surtout objectivés in vitro. Les études chez l’homme peinent à convaincre. Le GF est supplanté par le Coriolus versicolor, l’inégalable mycélium immunostimulant. En revanche, les données concordantes contre le syndrome métabolique éveillent un intérêt certain dans cette pathologie polymorphe fréquente — diabète, HTA, cholestérol, surpoids— où le prescripteur reste encore souvent démuni; même si aucune étude rando-misée de taille suffisante ne conforte les données obtenues chez l’animal.

Abstract

Maïtaké — Grifola frondosa (GF) — stimulates TH1 and TH2 pathways. TH1 pathway favors anti-fectious (listeria, herpes virus type 1 or influenza) or anti-cancer properties, mainly demonstrated by in vitro studies. Human randomized trials fail to convince. Coriolus versicolor — the immunostimulation leading mycelia — overtops GF. On the contrary, converging data regarding metabolic syndrome suggest an actual benefit of GF use against diabetes, hypertension, cholesterol excess or overweight. Nevertheless, appropriate randomized studies are still missing in those indications.

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    B. Donatini

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Donatini, B. Le Grifola frondosa (maïtaké) : un régulateur du syndrome métabolique: poids, cholestérol, glycémie et hypertension artérielle; accessoirement un immunostimulant. Phytothérapie 9, 376–379 (2011). https://doi.org/10.1007/s10298-011-0669-7

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