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Étude de l’activité virucide in vitro des Gouttes aux Essences® sur le virus para-influenzae de type 3

Study of virucidal activity in vitro of Gouttes aux Essences® on para-influenza type 3 virus

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Phytothérapie

Résumé

Le traitement par les huiles essentielles des infections respiratoires limite le recours systématique aux antibiotiques (Phytothérapie 6 (2004) 175–9). Plusieurs virus sont responsables de ces infections virales respiratoires: virus influenza, virus respiratoire syncytial, virus para-influenzae, adénovirus, rhinovirus... Cette étude a consisté à mettre en évidence l’activité virucide in vitro du produit Gouttes aux Essences®, complexe de cinq huiles essentielles vis-à-vis du virus para-influenzae de type 3, virus à ARN enveloppé appartenant au genre respirovirus. L’évaluation de l’activité virucide des huiles essentielles a été réalisée selon la norme NF EN 14476 + A1 (janvier 2007, phase 2, étape 1). Les huiles essentielles diluées à 20 et 80 %, mises en contact avec le virus para-influenzae de type 3 durant 60 minutes à 20 °C, présentent une activité virucide significative. Ce travail confirme l’intérêt et la pertinence de la prise en charge in vivo des infections virales respiratoires par les huiles essentielles qui peuvent ainsi compléter l’arsenal thérapeutique et limiter le recours indu aux antibiotiques.

Abstract

Respiratory tract infection treatment with essential oils limits the use of antibiotics (Phytothérapie 6 (2004) 175–9). Several different viruses cause those respiratory tract infections: influenza viruses, respiratory syncytial virus, para-influenza viruses, adenoviruses and rhinoviruses... The aim of this study was to show the virucidal action of Gouttes aux Essences®, a complex of five essential oils, against para-influenza type 3 virus, an enveloped RNA virus belonging to the genus respirovirus. The assessment of the virucidal activity of essential oils was performed according to the NF EN 14476 + A1 norm (janvier 2007, phase 2, étape 1) Essential oils, at 20 and 80% dilution, in contact with parainfluenza type 3 virus during 60 minutes at 20 °C, have a significant virucidal activity. This work confirms the interest and the relevance of the respiratory tract infections in vivo treatment with essential oils, which could complete the therapeutic choice and decrease antibiotic unnecessary use.

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Authors and Affiliations

  1. Laboratoire Fonderephar, faculté de pharmacie, 35, chemin des Maraîchers, F-31062, Toulouse cedex 04, France

    L. Haddioui

  2. Laboratoires Pierre Fabre, IRPF, 3, rue Ariane, F-31527, Ramonville, France

    B. Fabre

  3. Naturactive, Laboratoires Pierre Fabre, 15, avenue du Sidobre, F-81100, Castres, France

    P. Bruel

Authors
  1. L. Haddioui
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  2. B. Fabre
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  3. P. Bruel
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Correspondence to L. Haddioui.

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Haddioui, L., Fabre, B. & Bruel, P. Étude de l’activité virucide in vitro des Gouttes aux Essences® sur le virus para-influenzae de type 3. Phytothérapie 7, 313–315 (2009). https://doi.org/10.1007/s10298-009-0508-2

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  • DOI: https://doi.org/10.1007/s10298-009-0508-2

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